Newcastle University

Qualifications

BSc Biochemistry & Microbiology, University of Sheffield, 1987

PhD Biochemistry, University of Cambridge, 1992

Previous positions

Molecular Biologist, Novocastra Laboratories, 1992-1994

Research Associate, Virology Department, Newcastle University, 1994-2000

Senior Research Associate, Musculoskeletal Research Group, 2000-2006

Membership

Fellow of Higher Education Academy

Responsibilities

Senior tutor (SMBS)

Chair of Phase 2 Board of examiners (SBMS)

Chair of Phase 1 curriculum committee (SBMS)

Programme Co-ordinator for MSci Biomedical Sciences  

Faculty Regulations and Approvals Panel

University Regulations Committee 

Member of Senate

Research Background

Research background in virology and turnover of extracellular matrix. Expertise in molecular biology and recombinant protein expression.

Pedagogic Research Interests 

Differentiated learning; peer learning; attendance monitoring as a trigger for pastoral support 

Teaching

I teach on a range of modules on the undergraduate degree programmes in the School of Biomedical Sciences (SBMS).

Module leader for:  BGM1003 - Biochemistry; BGM2012 - Clinical Immunology & Viral pathogens; CMB3001 - Experimental design; BMS4099 - MSci Research project

• Bevitt D, Baldwin C, Calvert J. Intervening early: attendance and performance monitoring as a trigger for first year support in the biosciences. Bioscience Education 2010, 15(4).
• Fenwick F, Bassendine MF, Agarwal K, Bevitt D, Pumeechockchai W, Burt AD, Toms GL. Immunohistochemical assessment of hepatitis C virus antigen in cholestatic hepatitis after liver transplantation. Journal of Clinical Pathology 2006, 59(2), 174-178.
• Bevitt DJ, Li Z, Lindrop JL, Barker MD, Clarke MP, McKie N. Analysis of full length ADAMTS6 transcript reveals alternative splicing and a role for the 5′ untranslated region in translational control. Gene 2005, 359(1-2), 99-110.
• Nielsen SU, Bassendine MF, Burt AD, Bevitt DJ, Toms GL. Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver. Journal of General Virology 2004, 85(6), 1497-1507.
• Mckie JN, Mohamed J, Li Z, Arris CE, Hiscott P, Sheridan C, Langton KP, Barker MD, Clarke MP, Bevitt DJ. Expression of ADAMTS metalloproteinases in ARPE19 cells: Transcriptional regulation by TNF alpha. In: Investigative Ophthalmology & Visual Science: Annual Meeting of the Association for Research in Vision and Ophthalmology. 2003, Ft Lauderdale, Florida, USA: Association for Research in Vision and Ophthalmology.
• Bevitt DJ, Mohamed J, Catterall JB, Li Z, Arris CE, Hiscott P, Sheridan C, Langton KP, Barker MD, Clarke MP, McKie N. Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: Transcriptional regulation by TNFα. Biochimica et Biophysica Acta - Gene Structure and Expression 2003, 1626(1-3), 83-91.
• Barker MD, Arris CE, Bevitt DJ, Mohamed J, Li Z, Langton KP, Clarke MP, McKie N. Expression of mutant and wild type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients. In: Investigative Ophthalmology & Visual Science: Annual Meeting of the Association for Research in Vision and Ophthalmology. 2003, Ft Lauderdale, Florida, USA: Association for Research in Vision and Ophthalmology.
• Arris CE, Bevitt DJ, Mohamed J, Li Z, Langton KP, Barker MD, Clarke MP, McKie N. Expression of mutant and wild-type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients. Biochimica et Biophysica Acta - Molecular Basis of Disease 2003, 1638(1), 20-28.
• Pumeechockchai W, Bevitt D, Agarwal K, Petropoulou T, Langer BCA, Belohradsky B, Bassendine MF, Toms GL. Hepatitis C virus particles of different density in the blood of chronically infected immunocompetent and immunodeficient patients: Implications for virus clearance by antibody. Journal of Medical Virology 2002, 68(3), 335-342.
• Connor AL, Bevitt DJ, Toms GL. Comparison of human respiratory syncytial virus A2 and 8/60 fusion glycoprotein gene sequences and mapping of sub-group specific antibody epitopes. Journal of Medical Virology 2001, 63(2), 168-177.
• Lorite MJ, Bevitt DJ, Benitez J, McKie N, Day CP. Regulation of ADAMS family members in hepatic stellate cells by soluble growth factors: Evidence for their role in hepatic fibrogenesis. In: Hepatology. 2001.
• McKie JN, Bevitt DJ, Lorite MJ, Pimenides D, Clarke MP, Langton KP, Barker MD. RPE cells express several members of the metallo-disintegrin (ADAM) family of extracellular matrix modifying enzymes. Investigative Ophthalmology & Visual Science 2001, 42(4), 1197.
• Lorite MJ, Bevitt DJ, Benitez J, McKie N, Day CP. The ADAMs: A modular protein family with metalloproteinase and proteoglycan degrading activities expressed by the hepatic stellate cell. In: British Association for the Study of the Liver Meeting. 2001, University of Southampton: BMJ Publishing Group Ltd.
• Jackson M, Smith B, Bevitt DJ, Steward M, Toms GL, Bassendine MF, Diamond AG. Comparison of cytotoxic T-lymphocyte responses to hepatitis C virus core protein in uninfected and infected individuals. Journal of Medical Virology 1999, 58(3), 239-246.
• Fenwick F, Bevitt D, Burt AD, Pumeechockchai W, Bassendine MF, Toms GL. Detection of hepatitis C virus structural and nonstructural proteins by immunohistochemistry. In: Hepatology. 1999, John Wiley & Sons, Inc.
• F. Zappala, D. J. Bevitt, B. C. Smith, G. L. Toms and M. F. Bassendine. IgG anti HCV core recombinant protein titre correlates with biochemical activity, viraemia and fibrosis score in chronic hepatitis C. Gastroenterology 1997, 112, A1423-A1423.
• Bevitt D, Milton I, Piggot N, Henry L, Carter M, Toms G, Lennard TWJ, Westley B, Angus B, Horne C. New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry. Journal of Pathology 1997, 183(2), 228-232.
• Watson JP, Bevitt DJ, Spickett GP, Toms GL, Bassendine MF. Hepatitis C virus density heterogeneity and viral titre in acute and chronic infection: A comparison of immunodeficient and immunocompetent patients. Journal of Hepatology 1996, 25(5), 599-607.
• J. P. Watson, D. J. Bevitt, G. L. Toms and M. F. Bassendine. Hepatitis C virus E1 glycoprotein: Is a humoral immune response protective?. Hepatology 1996, 23, T73.
• Bevitt DJ, Cortes J, Haydock SF, Leadlay PF. 6-Deoxyerythronolide-B Synthase-2 From Saccharopolyspora erythraea - Cloning of the structural gene, sequence-analysis and inferred domain-structure of the multifunctional enzyme. European Journal of Biochemistry 1992, 204, 39-49.
• Caffrey P, Bevitt DJ, Staunton J, Leadlay PF. Identification of DEBS-1, DEBS-2 and DEBS-3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora-erythraea. Febs Letters 1992, 304, 225-228.
• Cortes J, Haydock SF, Roberts GA, Bevitt DJ, Leadlay PF. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora-erythraea. Nature 1990, 348, 176-178.