Newcastle University

Qualifications

BSc, PhD

Research Interests

Research interests in turnover of extracellular matrix. Expertise in molecular biology and recombinant protein expression.

• Bevitt DJ, Li Z, Lindrop JL, Barker MD, Clarke MP, McKie N. Analysis of full length ADAMTS6 transcript reveals alternative splicing and a role for the 5′ untranslated region in translational control. Gene 2005, 359(1-2), 99-110.
• Nielsen SU, Bassendine MF, Burt AD, Bevitt DJ, Toms GL. Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver. Journal of General Virology 2004, 85(6), 1497-1507.
• Bevitt DJ, Mohamed J, Catterall JB, Li Z, Arris CE, Hiscott P, Sheridan C, Langton KP, Barker MD, Clarke MP, McKie N. Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: Transcriptional regulation by TNFα. Biochimica et Biophysica Acta - Gene Structure and Expression 2003, 1626(1-3), 83-91.
• Pumeechockchai W, Bevitt D, Agarwal K, Petropoulou T, Langer BCA, Belohradsky B, Bassendine MF, Toms GL. Hepatitis C virus particles of different density in the blood of chronically infected immunocompetent and immunodeficient patients: Implications for virus clearance by antibody. Journal of Medical Virology 2002,68 3 335-342.
• Connor AL, Bevitt DJ, Toms GL. Comparison of human respiratory syncytial virus A2 and 8/60 fusion glycoprotein gene sequences and mapping of sub-group specific antibody epitopes. Journal of Medical Virology 2001, 63(2), 168-177.
• Jackson M, Smith B, Bevitt DJ, Steward M, Toms GL, Bassendine MF, Diamond AG. Comparison of cytotoxic T-lymphocyte responses to hepatitis C virus core protein in uninfected and infected individuals. Journal of Medical Virology 1999, 58(3), 239-246.
• Bevitt D, Milton I, Piggot N, Henry L, Carter M, Toms G, Lennard TWJ, Westley B, Angus B, Horne C. New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry. Journal of Pathology 1997, 183(2), 228-232.
• Watson JP, Bevitt DJ, Spickett GP, Toms GL, Bassendine MF. Hepatitis C virus density heterogeneity and viral titre in acute and chronic infection: A comparison of immunodeficient and immunocompetent patients. Journal of Hepatology 1996, 25(5), 599-607.
• Bevitt DJ, Cortes J, Haydock SF, Leadlay PF. 6-Deoxyerythronolide-B Synthase-2 From Saccharopolyspora erythraea - Cloning of the structural gene, sequence-analysis and inferred domain-structure of the multifunctional enzyme. European Journal of Biochemistry 1992, 204, 39-49.
• Caffrey P, Bevitt DJ, Staunton J, Leadlay PF. Identification of DEBS-1, DEBS-2 and DEBS-3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora-erythraea. Febs Letters 1992, 304, 225-228.
• Cortes J, Haydock SF, Roberts GA, Bevitt DJ, Leadlay PF. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora-erythraea. Nature 1990, 348, 176-178.
• Mckie JN, Mohamed J, Li Z, Arris CE, Hiscott P, Sheridan C, Langton KP, Barker MD, Clarke MP, Bevitt DJ. Expression of ADAMTS metalloproteinases in ARPE19 cells: Transcriptional regulation by TNF alpha. In: Investigative Ophthalmology & Visual Science: Annual Meeting of the Association for Research in Vision and Ophthalmology. 2003, Ft Lauderdale, Florida, USA: Association for Research in Vision and Ophthalmology.
• Barker MD, Arris CE, Bevitt DJ, Mohamed J, Li Z, Langton KP, Clarke MP, McKie N. Expression of mutant and wild type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients. In: Investigative Ophthalmology & Visual Science: Annual Meeting of the Association for Research in Vision and Ophthalmology. 2003, Ft Lauderdale, Florida, USA: Association for Research in Vision and Ophthalmology.