Prof. Nigel Robinson
Professor of Molecular Genetics
- Email: N.J.Robinson@ncl.ac.uk
- Telephone: +44 (0) 191 222 7695
- Fax: +44 (0) 191 222 7424
- Address: Cell & Molecular Biosciences, Medical School, Newcastle University, NE2 4HH, UK
Research Interests
THE MOLECULAR CELL BIOLOGY OF METALS About a third of proteins, and perhaps a half of enzymes, require metals. How do the correct metals locate to the correct proteins? Multiple partitioning events are generally required. My research group identify genes, and analyse their products, involved in the (i) perception-, (ii) acquisition or export-, (iii) intracellular distribution or storage-, of essential metals. The lab is funded by BBSRC.
ANNOUNCEMENTS
- Gordon conferences on 'The cell biology of metals'
- Nature protocol online: 'Metalloprotein metal pools: Identification and quantification by coupling native and non-native separations through principal component analysis'
- Nature podcast on 'Metalloproteins'
- Royal Society of Chemistry Journal on 'Metallomics'
- Meetings in 2010 'Metals in Biology' Asilomar, 'ASM' San Diego, 'Biometals' Tucson, 'Copper in Biology' Sardinia
Selected Publications
- Dainty SJ; Patterson CJ; Waldron KJ; Robinson NJ. Interaction between cyanobacterial copper chaperone Atx1 and zinc homeostasis. Journal of Biological Inorganic Chemistry 2010, 15(1), 77-85.
- Banci L; Bertini I; Ciofi-Baffoni S; Poggi L; Vanarotti M; Tottey S; Waldron KJ; Robinson NJ. NMR structural analysis of the soluble domain of ZiaA-ATPase and the basis of selective interactions with copper metallochaperone Atx1. Journal of Biological Inorganic Chemistry 2010, 15(1), 87-98.
- Waldron KJ; Rutherford JC; Ford D; Robinson NJ. Metalloproteins and metal sensing. Nature 2009. MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND: NATURE PUBLISHING GROUP, 460(7257), 823-830.
- Waldron KJ; Robinson NJ. How do bacterial cells ensure that metalloproteins get the correct metal?. Nature Reviews Microbiology 2009. MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND: NATURE PUBLISHING GROUP, 7(1), 25-35.
- Tottey S; Waldron KJ; Firbank SJ; Reale B; Bessant C; Sato K; Cheek TR; Gray J; Banfield MJ; Dennison C; Robinson NJ. Protein-folding location can regulate manganese-binding versus copper- or zinc-binding. Nature 2008, 455(7216), 1138-1142.
- Robinson NJ. A bacterial copper metallothionein. Nature Chemical Biology 2008, 4(10), 582-583.
Qualifications
University of Liverpool
Ph.D. Protein biochemistry (1981 - 1984)
BSc Class I (Hon.) Life Sciences (1978 - 1981)
Previous Positions
Professor of Genetics/Molecular Genetics (1994-present)
Newcastle University
Royal Society University Research Fellow (1987 - 1995)
Durham & Newcastle Universities
Postdoctoral Research Fellow (1984 - 1987)
Genetics Group, Los Alamos National Laboratory, New Mexico, USA
