2007-2009: Lecturer, Dermatological Sciences, Institute of Cellular Medicine, Newcastle University
Senior Lecturer in Cellular Dermatology and Oncology, Institute of Cellular Medicine, Newcastle University
Honary Senior Lecturer, Northern Institue of Cancer Research, Newcastle University
Member of Management board, Institute of Cellular Medicine
Teaching Co-ordinator, Institute of Cellular Medicine
Member of Post Graduate Committee, Institute of Cellular Medicine,
Committee member British Society for Investigative Dermatology
Grants advisory committee member for The British Skin Foundation
1992 MPhil, University of Newcastle upon Tyne and University of Nothumbria
1995 PhD, University of Newcastle upon Tyne and University of Northumbria
2006-2007: Academic Fellow, RCUK, Dermatological Sciences, School of Clinical & Laboratory Sciences, Newcastle University
2005-2006: Senior Research Associate, Dermatological Sciences, School of Clinical & Laboratory Sciences, Newcastle University
2004-2005, Senior Research Associate, Northern Institute of Cancer Research, Newcastle University
2000-2004, Senior Research Associate, Departments of Child Health and Medicine, University of Newcastle upon Tyne
1995-2001, Post Doctoral Research Associate, Departments of Child Health and Medicine, University of Newcastle upon Tyne
1988-1995, Research Associate, Departments of Child Health and Immunology, University of Newcastle upon Tyne
1987-1988, Medical Laboratory Scientific Officer,Department of Immunology, Newcastle General Hospital
Member of the British Assocation for Cancer Research
Member of the British Society for Investigative Dermatology
Member of the European Cell Death Organisation
Member of The European Society for Dermatological Research
Director of The North East Skin Research Fund
Visiting Professor Award, June-September 2006 University of Rome, 'Tor Vergata' Rome, Italy
Visiting Professor Award, February to June 2004 University of Rome, 'Tor Vergata' Rome, Italy
Visiting European Fellowship, March-May 2003, European Commission COST Action 44
Visiting Fellowship, April-June 2002 European Science Foundation
1997 UK Children's Cancer Study Group Young Investigator Award
1987 Northern Regional Health Authority, Sir William Leech Research Prize
Horse Riding, squash and Skiing.
Molecular biology and cellular signalling in skin cancer and inflammatory skin disease. Apoptotic and autophagic signalling in melanoma: development of novel therapeutic strategies and biomarkers.
Molecular biology of retinoid signalling in differentiation and apoptosis in neuroectodermal tumours
Targeting apoptosis/autophagy in melanoma. Development and validation of autophagy regulators as prognostic biomarkers for melanoma. Defining role of genetic mutations (including B-RAF) in melanoma development and progression. Translational research of novel agents for melanoma therapy in animal models.
Defining molecular mechanisms of autophagy and development of novel therapeutic strategies for inflammatory skin disease including psoriasis.
Principle Investiagtor of project grants to define role of apoptosis/autophagy in melanoma and the role of oncogenic B-RAF in melanoma dvelopment, progression and resistance to chemotherapy.
Principle investigator of international collaborative studies with the University of Rome, Tor Vergata and L'Spallanzani National Institute for Infectious Disease, Rome, Italy and the University of Ulm, Ulm, Germany
Supervision of PhD and MRes students
Personal tutor for home and international MRes (Medical and Molecular Biosciences)students
Deputy postgraduate tutor, Institute of Cellular Medicine
Teaching co-ordinator for Institute of Cellular Medicine
European Science Foundation Fellowship(2002)
European Commission COST Action 44 fellowship award (2003)
Visiting Professor Award, The University of Rome 'Tor Vergata' (2004, 2006)
Plenary Lecturer at The National Institute of Health and 'National Cancer Institute' USA, Oncology Seminar Programme (2005)
Member of Organising Committee for the 'European Cell Death Society'
Co-organiser of United Kingdom Children's Cancer Study Group, Neuroblastoma Conference, The Beehive, Newcastle University (February 2005)
Plenary speaker at keystone symposium 'Advances in the understanding and treatment of melanoma' (2006)
Invited speaker at EU FP7 Marie Curie Symposium 'The role of autophagy in Infectious Disease and Cancer', Rome, Italy (June, 2009)
Member of the Grants Advisory Committee, British Skin Foundation, 2011, Regular Reviewer for national and international reserach grant awarding bodies: Medical Reserach Council, Cancer Research UK, Association for International Cancer Research, The British Skin Foundation, The Neuroblastoma Society (UK), SPARKS, The Italian Association for Cancer Research, The Italian Neuroblastoma Society
Regular Reviewer for Scientific journals: The Journal of the National Cancer Institute, Cancer Research, International Journal of Cancer, British Journal of Cancer, Cell Death and Differentiation, FEBS letters, Journal of Investigative Dermatology, Clinical & Experimental Dermatology, British Journal of Dermatology
Cancer Research UK
British Skin Foundation
The Newcastle Health Care Charity
The JGW Patterson Foundation
The Neuroblastoma Society, UK
Association for international Cancer Research
Neuroblastoma Society, Italy
Italian Association for Cancer Research
Collaboration with Genesis Genomics UK
A company focused on the identification of bio-markers for the detection of melanoma.
Collaboration with Genzyme Inc, Boston, USA
January 2006 - Cancer Research Technology UK GB06009039
'Combining drugs protecting against ER stress in combination with ER-stress-inducing agents defines a novel and more effective theratpy for melanoma'
Inventors: Dr Penny Lovat, Professor Mark Birch-Machin, Dr Christopher Redfern
Supervision of BSc Biomedical Sciences student research projects.
Personal tutor BSc Biomedical Sciences home and international students
Supervison of PhD and MRes (Medical and Molecular Biosciences) students
Teaching and assessment of MRes (Medical and Molecular Biosciences) students (Cell signalling and Cancer study strands)
Personal Tutor to home and international MRes (Medical and Molecular Biosciences)students
Deputy post graduate tutor, Institute of Cellular Medicine
Teaching Co-ordinator, Institute of Cellular Medicine