Newcastle University

Roles and Responsibilities

Director , Anatomy and Clinical Skills.
Licensed Teacher of Anatomy.
Member of the School of Medical Education Development Executive Group.
MBBS UCAS Selector
MBBS Stage 1 Exam subCommittee
MBBS Stage 2 Exam subCommittee
MBBS Phase 1 Coordinating Committee
MBBS Phase 1 Staff/Student Committee
MBBS Phase 1 Life Cycle module leader
MBBS Faculty Progress Committee

Qualifications

BSc , PhD

Previous Positions

Research Associate, Reproductive Immunology Group, Department of Pathology, Bristol University . 1972-1980

• Scaife PJ, Bulmer JN, Robson SC, Innes BA, Searle RF. Effector activity of decidual CD8⁺ T lymphocytes in early human pregnancy. Biology of Reproduction 2006, 75(4), 562-567.
• Pongcharoen S, Somran J, Sritippayawan S, Niumsup P, Chanchan P, Butkhamchot P, Tatiwat P, Kunngurn S, Searle RF. Interleukin-17 Expression in the Human Placenta. Placenta 2007, 28(1), 59-63.
• Pongcharoen S, Bulmer JN, Searle RF. No evidence for apoptosis of decidual leucocytes in normal and molar pregnancy: Implications for immune privilege. Clinical and Experimental Immunology 2004, 138(2), 330-336.
• Pongcharoen S, Searle RF, Bulmer JN. Placental Fas and Fas ligand expression in normal early, term and molar pregnancy. Placenta 2004, 25(4), 321-330.
• Otun HA, Bulmer JN, Lash GE, Innes B, Schiessl B, Searle RF, Robson SC. Gestational changes in spiral artery vascular smooth muscle content using photoshop based image analysis. In: Journal of the Society for Gynecologic Investigation: 52nd Annual Meeting of the Society for Gynecologic Investigation. 2005, Los Angeles, California, USA: Sage Publications, Inc.
• Scaife PJ, Bulmer JN, Innes BA, Robson SC, Searle RF. Assessment of the cytolytic capability of decidual CD8+T lymphocytes in normal early pregnancy. In: Journal of the Society for Gynecologic Investigation: 52nd Annual Meeting of the Society for Gynecologic Investigation. 2005, Los Angeles, California, USA: Sage Publications, Inc.
• Otun HA, Lash GE, Innes B, Schiessl B, Searle RF, Robson SC, Bulmer JN. Gestational changes in spiral artery vascular smooth muscle content using photoshop based image analysis. In: Journal of the Society for Gynecologic Investigation: 52nd Annual Meeting of the Society for Gynecologic Investigation. 2005, Los Angeles, California, USA: Sage Publications, Inc.
• Lash GE, Otun HA, Bulmer JN, Searle RF, Robson SC. Inhibition of extravillous trophoblast invasion by TGF-beta 1, 2 and 3 is associated with a reduction in secreted MMP-9 levels. In: Journal of the Society for Gynecologic Investigation: 52nd Annual Meeting of the Society for Gynecologic Investigation. 2005, Los Angeles, California, USA: Sage Publications, Inc.
• Lash GE, Otun HA, Innes BA, Bulmer JN, Searle RF, Robson SC. Inhibition of trophoblast cell invasion by TGFB1, 2, and 3 is associated with a decrease in active proteases. Biology of Reproduction 2005, 73(2), 374-381.
• Sakamoto Y, Moran P, Bulmer JN, Searle RF, Robson SC. Macrophages and not granulocytes are involved in cervical ripening. Journal of Reproductive Immunology 2005, 66(2), 161-173.
• Lash GE, Otun HA, Bulmer JN, Searle RF, Robson SC. TNF-alpha and IFN-gamma inhibit extravillous trophoblast invasion in a paracrine manner via a mechanism independent of MMP-2 or MMP-9 levels. In: 52nd Annual Scientific Meeting of the Society for Gynecologic Investigation. 2005, Los Angeles, California: Journal of the Society for Gynecologic Investigation, Sage Publications.
• Scaife PJ, Searle RF, Innes BA, Robson SC, Bulmer JN. Cytokine production by CD8+ decidual leucocytes in early pregnancy. Gynecologic and Obstetric Investigation 2004, 11(2, Supplement), 628A.
• Sakamoto Y, Moran P, Searle RF, Bulmer JN, Robson SC. Interleukin-8 is involved in cervical dilatation but not in prelabour cervical ripening. Clinical and Experimental Immunology 2004, 138(1), 151-157.
• Scaife PJ, Searle RF, Robson SC, Innes BA, Bulmer JN. [abstract] A comparison of cytotoxic decidual lymphocytes in early and late pregnancy. Journal of the Society for Gynecologic Investigation 2003, 10(2 (supplement)), 360A.
• Otun HA, Lash GE, Bulmer JN, Searle RF, Robson SC. Inhibition of first trimester human extravillous trophoblast invasion by TNF-alpha and IFN-gamma. In: 10th European Placenta Group Meeting: Comparative, Experimental and Clinical Aspects of Placentation. 2003, Mainz, Germany.
• Bulmer JN, Innes BA, Searle RF, Robson SC. M30 is expressed by extravillous trophoblast in the placental bed in the first half of normal human pregnancy. Journal of the Society for Gynecologic Investigation 2003, 10(2 (supplement)), 394A.
• Otun HA, Searle RF, Bulmer JN, Robson SC. The effect of gestational age on trophoblast invasion. Journal of the Society for Gynecologic Investigation 2003, 10(2, supplement), 398A.
• Otun HA, Searle RF, Bulmer JN, Robson SC. The effect of TGF beta inhibition on trophoblast invasion. Journal of the Society for Gynecologic Investigation 2003, 10(2 (Supplement)), 397A.
• Phillips PJ, Innes BA, Searle RF, Bulmer JN, Robson SC. [abstract] Use of laser capture microdissection and RT-PCR to study gene expression in heterogeneous differentiating trophoblast populations. Journal of the Society for Gynecologic Investigation 2003, 10(2, supplement), 398A.
• Pongcharoen S, Bulmer JN, Searle RF. Lack of apoptotic decidual leucocytes in hydatidiform mole: no evidence for Fas-Fas ligand system mediated maternal T cell tolerance in molar pregnancy. Immunology 2002, 107(s1), 124.
• Searle RF, Wongweragiat S, Bulmer JN. Maternal immune tolerance during molar pregnancy: increased expression of Fas ligand on abnormal trophoblast induces apoptosis of activated decidual leucocytes. In: VIII International Congress of Reproductive Immunology. 2001, Opatija, Croatia: Wiley-Blackwell Publishing, Inc.
• Stewart JA, Bulmer JN, Searle RF, Murdoch AP. Endometrial steroid hormone receptor in relation to unexplained sub-fertility and parity. J Reproduction and Fertility 2000, Abstract Series No 25, 46.
• Lash GE, Naruse K, Robson A, Innes BA, Searle RF, Robson SC, Bulmer JN. Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production. Human Reproduction 2011, 26(9), 2289-2295.
• Lash GE, Naruse K, Robson A, Innes BA, Searle RF, Robson SC, Bulmer JN. Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production. In: Journal of Reproductive Immunology: 9th Congress of the European Society for Reproductive Immunology. 2011, Copenhagen, Denmark: Elsevier Ireland Ltd.
• Scaife PJ, Searle RF, Robson SC, Innes BA, Bulmer JN. Comparison of decidual leucocyte populations in spontaneous early pregnancy loss. In: Journal of the Society for Gynecologic Investigation. 2004, Houston, Texas, USA: Sage Publications Ltd.
• Lash GE, Otun HA, Innes B, Searle RF, Bulmer JN, Robson SC. Culture of placental villous explants in 8% oxygen does not alter their invasive phenotype. In: Conference of the Placenta Association of the Americas/10th Meeting of the International Federation of Placenta. 2004, Asilomar, CA: Placenta: WB Saunders Co. Ltd.
• Scaife PJ, Searle RF, Robson SC, Innes BA, Bulmer JN. Cytokine production by CD8+decidual leucocytes in early pregnancy. In: Journal of the Society for Gynecologic Investigation: 51st Annual Meeting of the Society for Gynecologic Investigation. 2004, Houston, Texas, USA: Sage Publications, Inc.
• Lash GE, Otun HA, Innes B, Searle RF, Bulmer JN, Robson SC. Inhibition of extravillous trophoblast cell invasion in 3% oxygen is due to an increase in PAI-2 production. In: Conference of the Placenta Association of the Americas/10th Meeting of the International Federation of Placenta. 2004, Asilomar, CA: Placenta: WB Saunders Co. Ltd.
• Lash GE, Otun HA, Innes B, Bulmer JN, Searle RF, Robson SC. Invasion of extravillous trophoblast cells is inhibited in low oxygen conditions. In: Journal of the Society for Gynecologic Investigation. 2004, Houston, Texas, USA: Sage Publications, Inc.
• Otun HA, Lash GE, Innes B, Bulmer JN, Searle RF, Robson SC. Regulation of trophoblast invasion by TGF-beta: Role of apoptosis and proliferation. In: Journal of the Society for Gynecologic Investigation. 2004, Houston, Texas, USA: Sage Publications Ltd.
• Searle RF. So you want to be an anatomy demonstrator. Northern Newsletter 2002, 13, 8-9.
• Wongweragiat S, Searle RF, Bulmer JN. Expression of Fas/Fas ligand by decidual leukocytes in hydatidiform mole. Biology of Reproduction 2001, 64(3), 784-789.
• Bromage SJ, Lang AK, Atkinson I, Searle RF. Abnormal TGFβ levels in the amniotic fluid of Down syndrome pregnancies. American Journal of Reproductive Immunology 2000, 44(4), 205-210.
• Searle RF, Bromage SJ, Palmer J, Curry JE, Lang AK. Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the β-chain of the interleukin-2 receptor. Immunology 2000, 99(3), 411-417.
• Wongweragiat S, Searle RF, Bulmer JN. Decidual T lymphocyte activation in hydatidiform mole. Journal of Clinical Pathology 1999, 52(12), 888-894.
• Vassiliadou N, Searle RF, Bulmer JN. Elevated expression of activation molecules by decidual lymphocytes in women suffering spontaneous early pregnancy loss. Human Reproduction 1999, 14(5), 1194-1200.
• Searle RF, Jones RK, Bulmer JN. Phenotypic analysis and proliferative responses of human endometrial granulated lymphocytes during the menstrual cycle. Biology of Reproduction 1999, 60(4), 871-878.
• Swamy M, Bloomfield TC, Thomas RH, Singh H, Searle RF. Role of SimMan in teaching clinical skills to preclinical medical students. BMC Medical Education 2013, 13(1), 20.
• Swamy M, Searle RF. Anatomy teaching with portable ultrasound to medical students. BMC Medical Education 2012, 12(1), 99.
• Overbeck-Zubrzycka D, Krishnan A, Hamilton DW, Searle RF, Stansby G. Tomorrow’s Doctors: students’ satisfaction with a prosection-based undergraduate anatomy course. Bulletin of The Royal College of Surgeons of England 2012, 94(1), 1-4.