Publication:

Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide (1994)

Author(s): Walker, D., Flinois, J. P., Monkman, S. C., Beloc, C., Boddy, A. V., Cholerton, S., Daly, A. K., Lind, M. J., Pearson, A. D. J., Beaune, P. H., Idle, J. R.

      • Date: 1994-03-29
      • Journal: Biochemical Pharmocology
      • Volume: 47
      • Issue: 7
      • Pages: 1157-1163
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: CYTOCHROME P450 3A4 INHIBITION NARINGENIN TRIACETYLOLEANDOMYCIN WESTERN BLOTTING CORRELATION OXIDATIVE DRUG-METABOLISM HUMAN-LIVER GENETIC-POLYMORPHISM CYCLOPHOSPHAMIDE RAT PHARMACOKINETICS 4-HYDROXYCYCLOPHOSPHAMIDE PURIFICATION CYCLOSPORINE EXPRESSION