Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency (2011)

Author(s): Hardcastle IR, Liu J, Valeur E, Watson A, Ahmed SU, Blackburn TJ, Bennaceur K, Clegg W, Drummond C, Endicott JA, Golding BT, Griffin RJ, Gruber J, Haggerty K, Harrington RW, Hutton C, Kemp S, Lu X, McDonnell JM, Newell DR, Noble ME, Payne SL, Revill CH, Riedinger C, Xu Q, Lunec J

      • Date: 11-02-2011
      • Journal: Journal of Medicinal Chemistry
      • Volume: 54
      • Issue: 5
      • Pages: 1233-1243
      • Publisher: American Chemical Society
      • Publication type: Article
      • Bibliographic status: Published

      Professor Jane Endicott
      Prof of Cancer Structural Biology

      Professor John Lunec
      Gillespie Prof of Molecular Oncology

      Professor Martin Noble
      Prof of Biom Struct & Anticanc Drug Des