Publication:

Tetrahydrobenzothiophene Derivatives: Conformationally Restricted Inhibitors of Type II Dehydroquinase (2011)

Author(s): Paz S, Tizon L, Otero JM, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Lapthorn AJ, Castedo L, Gonzalez-Bello C

      • Date: 01-02-2011
      • Journal: ChemMedChem
      • Volume: 6
      • Issue: 2
      • Pages: 266-272
      • Publisher: Wiley - VCH Verlag GmbH & Co. KGaA
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: competitive inhibitors Helicobacter pylori Mycobacterium tuberculosis restricted conformation stable ozonides NANOMOLAR COMPETITIVE INHIBITORS STRUCTURE-BASED DESIGN STREPTOMYCES-COELICOLOR BIOLOGICAL EVALUATION MYCOBACTERIUM-TUBERCULOSIS CRYSTAL-STRUCTURES SHIKIMATE PATHWAY ESSENTIAL GENES ACTIVE-SITE ACIDS

      Staff

      Professor Alastair Hawkins
      Professor of Molecular Genetics