Publication:

A Prodrug Approach for Improving Antituberculosis Activity of Potent Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors (2011)

Author(s): Tizon L, Otero JM, Prazeres VFV, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Ainsa JA, Castedo L, Gonzalez-Bello C

      • Date: 22-07-2011
      • Journal: Journal of Medicinal Chemistry
      • Volume: 54
      • Issue: 17
      • Pages: 6063-6084
      • Publisher: American Chemical Society
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: NANOMOLAR COMPETITIVE INHIBITORS ELECTROSPRAY MASS-SPECTROMETRY STREPTOMYCES-COELICOLOR BIOLOGICAL EVALUATION STEREOCHEMICAL COURSES SHIKIMATE PATHWAY CRYSTALLOGRAPHY DESIGN INTERMEDIATE VALIDATION

      Staff

      Professor Alastair Hawkins
      Professor of Molecular Genetics