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Liver Research Group

The group is internationally recognised in the field of liver research.

Theme Leader

Professor Derek Mann (Head of Research Group) and Dr Quentin M. Anstee (Clinical Research Lead)

Major Research Themes

The Newcastle Liver Research Group maintains critical mass to support on-going research in the field of hepatology, genetics and liver biology and provides a forum to support bi-directional translational research and collaboration.

Expertise

With a membership comprising basic-scientists and clinician-scientists, the liver research group provides a forum for 'cross-pollination' of ideas between related disciplines. This grouping has already successfully translated a number of basic research projects 'to the bedside' where clinical trials are on-going examining novel anti-fibrotic approaches to slow fibrosis in fatty liver disease.

Members of the group are advancing research in the fields of:

non-alcoholic fatty liver disease (NAFLD)
primary biliary cirrhosis (PBC)
alcoholic liver disease
hepatocellular carcinoma (HCC)
genetic and epigenetic modifiers of liver disease severity (in patient cohorts and animal models)
tissue fibrosis

Within these areas we are leaders in several national and international clinical research collaborations including the ‘UK Genetics of Liver Disease’ (UK GoLD) consortium, ‘Fatty Liver Inhibition of Progression’ (FLIP) consortium and the ‘UK-PBC’ consortium.

Related Websites

Institute of Cellular Medicine

Staff List

Rg_liver
Dr Quentin Anstee Clinical Senior Lecturer & Consultant Hepatologist	Email: quentin.anstee@ncl.ac.uk Telephone: +44 (0) 191 222 7012
Professor Margaret Bassendine Strategic Research Advisor	Email: margaret.bassendine@ncl.ac.uk Telephone: +44 (0) 191 213 7208
Professor Alastair Burt	Email: alastair.burt@ncl.ac.uk Telephone: +44 (0) 191 282 0700
Professor Ann Daly Professor of Pharmacogenetics	Email: a.k.daly@ncl.ac.uk Telephone: +44 (0) 191 222 7031
Professor Chris Day PVC/Provost of Medical Sciences	Email: chris.day@ncl.ac.uk Telephone: +44 (0) 191 222 7003
Dr Peter Donaldson Senior Lecturer	Email: peter.donaldson@ncl.ac.uk Telephone: +44 (0) 191 222 8868
Professor David Jones Dean of Translational Research	Email: david.jones@ncl.ac.uk Telephone: +44 (0) 191 222 8696
Professor John Kirby Professor of Immunobiology	Email: john.kirby@ncl.ac.uk Telephone: +44 (0) 191 222 7057
Professor Derek Manas Hon Clin Prof of Transplantation
Dr Jelena Mann Reader in Epigenetics	Email: jelena.mann@ncl.ac.uk Telephone: +44 (0) 191 222 5902
Professor Derek Mann Prof of Hepatology	Email: derek.mann@ncl.ac.uk Telephone: +44 (0) 191 222 3851
Dr Fiona Oakley Reader in Fibrosis Biology	Email: fiona.oakley@ncl.ac.uk Telephone: +44 (0) 191 222 3852
Dr Helen Reeves Senior Lecturer & Honorary Consultant Gastroenterologist at Newcastle Hospitals NHS Foundation Trust	Email: helen.reeves@ncl.ac.uk Telephone: +44 (0) 191 246 4423
Professor Geoff Toms Guest	Email: geoffrey.toms@ncl.ac.uk Telephone: +44 (0) 191 222 7629
Professor Matthew Wright Professor of Toxicology	Email: matthew.wright@ncl.ac.uk Telephone: +44 (0) 191 222 7094

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