Professor Andrew CantHon Clin Prof Paediatric Immunology
Cole TS, Jones LKR, McGrogan P, Pearce MS, Flood TJ, Cant AJ, Goldblatt D, Thrasher AJ, Gennery AR, McKendrick F, Titman P. Emotional and behavioural difficulties in chronic granulomatous disease .
Archives of Disease in Childhood 2012, 97 (1), 87-87.
Moreira D, Slatter M, Nademi Z, Brigham K, Barge D, Jackson A, Flood T, Cant A, Abinun M, Hambleton S, Gennery A. Immune reconstitution and clinical outcome after HSCT infusion for severe combined immunodeficiency in Newcastle .
In: Biology of Blood and Marrow Transplantation: BMT Tandem Meeting . 2012, San Diego, California, USA: Elsevier Inc.
Cole TS, Johnstone IC, Pearce MS, Fulton B, Cant AJ, Gennery AR, Slatter MA. Outcome of children requiring intensive care following haematopoietic SCT for primary immunodeficiency and other non-malignant disorders .
Bone Marrow Transplantation 2012, 47 (1), 40-45.
Subbarayan A, Colarusso G, Hughes SM, Gennery AR, Slatter M, Cant AJ, Arkwright PD. Clinical Features That Identify Children With Primary Immunodeficiency Diseases .
Pediatrics 2011, 127 (5), 810-816.
Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Spence L, Pagan S, Carey C, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Jackson G, Dick JE, Hambleton S, Collin M. Dendritic cell, monocyte, B and NK lymphoid deficiency: a novel but potentially fatal haematological disorder curable with haematopoietic stem cell transplantation .
In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation . 2011, Paris, France: Nature Publishing Group.
Dickinson RE, Griffin H, Bigley V, Reynard LN, Hussain R, Haniffa M, Lakey JH, Rahman T, Wang XN, McGovern N, Pagan S, Cookson S, McDonald D, Chua I, Wallis J, Cant A, Wright M, Keavney B, Chinnery PF, Loughlin J, Hambleton S, Santibanez-Koref M, Collin M. Exome sequencing identifies GATA-2 mutation as the cause of the dendritic cell, monocyte, B and NK lymphoid deficiency .
Blood 2011, 118 (10), 2656-2658.
Slatter MA, Cant AJ. Hematopoietic stem cell transplantation for primary immunodeficiency diseases .
In: Casanova, J.L., Conley, M.E., Notarengelo, L, ed. The Year in Human and Medical Genetics: Inborn Errors of Immunity I . Oxford, UK: Wiley-Blackwell, 2011, pp.122-131.
Lane JP, Evans PTG, Slatter MA, Barge D, Jackson A, Hambleton S, Flood T, Abinun M, Cant J, Gennery A. Immune reconstitution post umbilical cord blood stem cell transplantation for primary immunodeficiency in a national centre .
In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation . 2011, Paris, France: Nature Publishing Group.
Hambleton S, Salem S, Bustamente J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez C, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, Alsina L, Zumwalt TJ, Kong X, Kumararatne D, Butler K, Hubeau M, Feinberg J, Al-Muhsen S, Cant A, Abel L, Chaussabel D, Doffinger R, Talesnik E, Grumach A, Duarte A, Abarca K, Moraes-Vasconcelos D, Burk D, Berghuis A, Geissmann F, Collin M, Casanova J-L, Gros P. IRF8 Mutations and Human Dendritic-Cell Immunodeficiency .
New England Journal of Medicine 2011, 365 (2), 127-138.
Moratto D, Giliani S, Bonfim C, Mazzolari E, Fischer A, Ochs HD, Cant AJ, Thrasher AJ, Cowan MJ, Albert MH, Small T, Pai SY, Haddad E, Lisa A, Hambleton S, Slatter M, Cavazzana-Calvo M, Mahlaoui N, Picard C, Torgerson TR, Burroughs L, Koliski A, Zanis-Neto J, Porta F, Qasim W, Veys P, Kavanau K, Hönig M, Schulz A, Friedrich W, Notarangelo LD. Long-term outcome and lineage-specific chimerism in 194 Wiskott-Aldrich Syndrome patients treated by hematopoietic cell transplantation between 1980-2009: an international collaborative study .
Blood 2011, 118 (6), 1675-1684.
Morgan NV, Goddard S, Cardno TS, McDonald D, Rahman F, Barge D, Ciupek A, Straatman-Iwanowska A, Pasha S, Guckian M, Anderson G, Huissoon A, Cant A, Tate WP, Hambleton S, Maher ER. Mutation in the TCR alpha subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCR alpha beta(+) T cells .
European Journal of Clinical Investigation 2011, 121 (2), 695-702.
Brown L, Xu-Bayford J, Allwood Z, Slatter M, Cant A, Davies EG, Veys P, Gennery AR, Gaspar HB. Neonatal Diagnosis of Severe Combined Immunodeficiency Leads to Significantly Improved Survival Outcome: The Case for Newborn Screening [editorial comment] .
Obstetrical & Gynecological Survey 2011, 66 (7), 398-399.
Slatter MA, Angus B, Windebank K, Taylor A, Meaney C, Lester T, Norbury G, Hambleton S, Abinun M, Flood TJ, Cant AJ, Gennery AR. Polymorphous lymphoproliferative disorder with Hodgkin-like features in common gamma-chain-deficient severe combined immunodeficiency .127 (2), 533-535.
Sturgess K, Slatter M, Bigley V, Haniffa M, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Chua I, Wallis J, Lordan J, Morgan C, Cant A, Gennery A, Edmondson R, Bacon C, Black F, Kirkham N, Jackson GH, Hambleton S, Collin MP. Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation .
In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH) . 2011, San Diego, California, USA: American Society of Hematology.
Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Dick JE, Hambleton S, Collin M. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency .
Journal of Experimental Medicine 2011, 208 (2), 227-234.
Slatter MA, Rao K, Amrolia P, Flood T, Abinun M, Hambleton S, Nademi Z, Goulden N, Davies G, Qasim W, Gaspar HB, Cant A, Gennery AR, Veys P. Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience .
Blood 2011, 117 (16), 4367-4375.
Daikeler T, Labopin M, Socie G, Faraci M, Rahman FA, Yesilipek A, Arcese W, Meara AO, Sirvent A, Voswinkel J, Verdeguer A, Gandemer V, Schoemans H, Cant AJ, Messina C, Sedlacek P, Vora AJ, Mialou V, Diez JL, Sora F, Jubert C, Herr AL, Ruggeri A, Crotta A, Gluckman E, Farge D, Rocha V. Incidence and Risk Factors for Secondary Autoimmune Diseases (AD) After Cord Blood Transplantation (CBT) Retrospective Analysis on Behalf of Eurocord and the EBMT Autoimmune Diseases Working Party .
In: 52nd Annual Meeting of the American Society of Hematology . 2010, Orlando, FL: Blood: American Society of Hematology.
Gallimore CI, Lewis D, Taylor C, Cant A, Gennery A, Gray JJ. Chronic excretion of a recombinant norovirus in a child with cartilage hair hypoplasia (CHH) .
Journal of Clinical Virology 2004, 30 (2), 196-204.
Fenton AC, Berrington JE, Spickett GP, Cant AJ, O'Keeffe M, Matthews JN. Haemaphilus influenzaeType b (Hib) antibody response following pragmatic UK immunisation with mixed regimes of acellular and/or whole cell DTPHib combination vaccines .
In: Annual Meeting of the Pediatric Academic Societies . 2004, San Francisco, CA: Pediatric Research: International Pediatric Research Foundation.
Atherton DJ, Gennery AR, Cant AJ. The Neonate - Cutaneous features of primary immunodeficiency disorders .
In: Burns, T., Griffiths, C., Cox, N., Breathnach, S., ed. Rook’s Textbook of Dermatology . Oxford, UK: Wiley-Blackwell, 2004, pp. chapter 14.
Berrington JE, Fenton AC, Spickett GP, Cant AJ. Haemophilus influenzae type b (Hib) antibody response in significantly preterm UK infants .
In: Pediatric Research: Annual Meeting of the Pediatric Academic Society . 2003, Seattle, Washington, USA: Lippincott Williams & Wilkins.
Cant AJ, Gibb D, Davies EG, Cale C, Gennery AR. Immunodeficiency .
In: McIntosh, N., Helms, P., Smyth, R, ed. Forfar and Arneil’s Textbook of Pediatrics . Edinburgh, UK: Churchill Livingston, 2003, pp.chapter 25.
Driessen GJA, Gerritsen EJA, Fischer A, Fasth A, Hop WCJ, Veys P, Porta F, Cant A, Steward CG, Vossen JM, Uckan D, Friedrich W. Long-term outcome of haematopoietic stem cell transplantation in autosomal recessive osteopetrosis: an EBMT report .
Bone Marrow Transplantation 2003, 32 (7), 657-663.
Gennery AR, Barge D, O'Sullivan JJ, Flood TJ, Abinun M, Cant AJ. Antibody deficiency and autoimmunity in 22q11.2 deletion syndrome .
Archives of Disease in Childhood 2002, 86 (6), 422-425.
Arkwright PD, Abinun M, Cant AJ. Autoimmunity in human primary immunodeficiency diseases .
Blood 2002, 99 (8), 2694-2702.
Krishna MT, Hodges E, Lavender FL, Harris S, Gennery A, Cant A, Gibson B, Wilkie R, Darbyshire P, Smith JL. CD3+CD4-CD8+NK- large granular lymphocytosis with neutropenia and evidence for clonality and T-Cell receptor gene rearrangement: Two pediatric cases .
Journal of Pediatric Hematology / Oncology 2002, 24 (6), 495-498.
Gennery AR, Cant AJ. Development of allergy post-bone marrow transplantation .
Clinical and Experimental Allergy 2002, 32 (12), 1677-1678.
Clark J, Lakshman R, Galloway A, Cant A. Does cefotaxime eradicate nasopharyngeal carriage of N meningiditis .
Archives of Disease in Childhood 2002, 87 (5), 449-449.
Dickinson A, Cant A. Haemopoietic stem-cell transplantation: improving immune reconstitution, avoiding graft-versus-host disease .
Lancet 2002, 360 (9327), 98-99.
Macdougall CF, Cant AJ, Colver AF. How dangerous is food allergy in childhood? The incidence of severe and fatal allergic reactions across the UK and Ireland .
Archives of Disease in Childhood 2002, 86 (4), 236-239.
Arkwright PD, McDermottt MF, Houten SM, Frenkel J, Waterhan HR, Aganna E, Hammond LJ, Mirakian RM, Tomlin P, Vijaydurai PI, Cant AJ. Hyper IgD syndrome (HIDS) associated with in vitro evidence of defective monocyte TNFRSF1A shedding and partial response to TNF receptor blockade with etanercept .
Clinical and Experimental Immunology 2002, 130 (3), 484-488.
Colver A, Macdougall C, Cant A. Incidence of severe and fatal reactions to foods - Reply .
Archives of Disease in Childhood 2002, 87 (5), 451.
Hoare S, El-Shazali O, Clark JE, Fay A, Cant AJ. Investigation for complement deficiency following meningococcal disease .
Archives of Disease in Childhood 2002, 86 (3), 215-217.
Jones L, Flood TJ, McGrogan P, Morton L, Parker L, Goldblatt D, Thrasher A, Cant AJ. Respiratory disease in Chronic Granulomatous Disease .
In: Thorax: Winter Meeting of the British Thoracic Society . 2002, London: BMJ Group.
Dziembowska M, Fondaneche MC, Vedrenne J, Barbieri G, Wiszniewski W, Picard C, Cant AJ, Steimle V, Charron D, Alca-Loridan C, Fischer A, Lisowska-Grospierre B. Three novel mutations of the CIITA gene in MHC class II-deficient patients with a severe immunodeficiency .
Immunogenetics 2002, 53 (10-11), 821-829.
Riordan FAI, Cant AJ. When to do a lumbar puncture .
Archives of Disease in Childhood 2002, 87 (3), 235-237.
Gennery AR, Cant AJ. Applied Physiology: Immune Competence .
Current Paediatrics 2001, 11 (6), 458-464.
Khawaja K, Gennery AR, Flood TJ, Abinun M, Cant AJ. Bone marrow transplantation for CD40 ligand deficiency: a single centre experience .
Archives of Disease in Childhood 2001, 84 (6), 508-511.
Gennery AR, Dickinson AM, Brigham K, Barge D, Spickett GP, Curtis A, Spencer V, Jackson A, Carter V, Palmer P, Flood TJ, Cant AJ, Abinun M. CAMPATH-1M T-cell depleted BMT for SCID: long-term follow-up of 19 children treated 1987-98 in a single center .
Cytotherapy 2001, 3 (3), 221-232.
Gennery AR, Dickinson AM, Brigham K, Barge D, Spickett GP, Curtis A, Spencer V, Jackson A, Cavanagh G, Carter V, Palmer P, Flood TJ, Cant AJ, Abinun M. CAMPATH-1M T-cell depleted BMT for SCID: Long-term follow-up of 19 children treated 1987-98 in a single center .
Cytotherapy 2001, 3 (3), 221-232.
Gennery AR, Cant AJ, Baldwin CI, Calvert JE. Characterization of the impaired antipneumococcal polysaccharide antibody production in immunosuppressed pediatric patients following cardiac transplantation .
Journal of Clinical Immunology 2001, 21 (1), 43-50.
Gennery AJ, Cant A, Forsyth RJ. Development of parainfectious opsoclonus in an infant by a non-humoral immune mechanism .
Developmental Medicine and Child Neurology 2001, 43 (3), 213-214.
Gennery AR, Cant AJ. Diagnosis of severe combined immunodeficiency .
Journal of Clinical Pathology 2001, 54 (3), 191-195.
Gennery AR, Barge D, Spickett GP, Cant AJ. Lymphocyte subset populations in children with polysaccharide antibody deficiency following cardiac transplantation .
Journal of Clinical Immunology 2001, 21 (1), 37-42.
Kane L, Gennery AR, Crooks BNA, Flood TJ, Abinun M, Cant AJ. Neonatal bone marrow transplantation for severe combined immunodeficiency .
Archives of Disease in Childhood: Fetal and Neonatal Edition 2001, 85 (2), F110-F113.
Khawaja K, Gennery AR, Abinun M, Flood TJ, Cant AJ. Single Supraregional Centre Experience of Bone Marrow Transplantation for CD40L Deficiency .
Archives of Disease in Childhood 2001, 84 (6), 508-511.
Nademi Z, Clark J, Richards CGM, Walshaw D, Cant AJ. The causes of fever in children attending hospital in the North of England .
Journal of Infection 2001, 43 (4), 221-225.
Aladangady N, Kinmond S, Cant AJ, Gibson B, Coutts JAP. A preterm baby with Omenn syndrome .
European Journal of Pediatrics 2000, 159 (9), 657-658.
Gennery AR, Flood TJ, Abinun M, Cant AJ. Bone marrow transplantation does not correct the hyper IgE syndrome .
Bone Marrow Transplantation 2000, 25 (12), 1303-1305.
Saleem MA, Arkwright PD, Davies EG, Cant AJ, Veys PA. Clinical course of patients with major histocompatibility complex class II deficiency .
Archives of Disease in Childhood 2000, 83 (4), 356-359.
Drummond P, Clark J, Wheeler J, Galloway A, Freeman R, Cant A. Community acquired pneumonia - a prospective UK study .
Archives of Disease in Childhood 2000, 83 (5), 408-412.
Arkwright PD, Rieux-Laucat F, Le Deist F, Stevens RF, Angus B, Cant AJ. Cytomegalovirus infection in infants with autoimmune lymphoproliferative syndrome (ALPS) .
Clinical and Experimental Immunology 2000, 121 (2), 353-357.
Gennery AR, Cant AJ, Jeggo PA. Immunodeficiency associated with DNA repair defects .
Clinical and Experimental Immunology 2000, 121 (1), 1-7.
Srinivasan M, Abinun M, Cant AJ, Tan K, Oakhill A, Steward CG. Malignant infantile osteopetrosis presenting with neonatal hypocalcaemia .
Archives of Disease in Childhood: Fetal & Neonatal 2000, 83 (1), F21-F23.
Crooks BNA, Taylor CE, Turner AJL, Osman HKE, Abinun M, Flood TJ, Cant AJ. Respiratory viral infections in primary immune deficiencies: significance and relevance to clinical outcome in a single BMT unit .
Bone Marrow Transplantation 2000, 26 (10), 1097-1102.
Gennery AR, Clark JE, Flood TJ, Cant AJ. T-cell-depleted bone marrow transplantation from unrelated donor for [correction of allogeneic sibling for] X-linked hyperimmunoglobulin M syndrome .
Journal of Pediatrics 2000, 137 (2), 290-290.
Berrington JE, Flood TJ, Abinun M, Galloway A, Cant AJ. Unsuspected Pneumocystis carinii pneumonia at presentation of severe primary immunodeficiency .
Archives of Disease in Childhood 2000, 82 (2), 144-147.
