Newcastle University

Roles and Responsibilities

Group Leader

ICM Postgraduate Coordinator 
Chair Postgraduate Committee (ICM)

Management Committee (ICM)

Faculty PGR Committee
PhD, MRes and UG student supervisor
PhD external and internal examiner
PhD, MD and MPhil progress assessor
ICM seminar co-ordinator
UG student personal tutor
MBBS student annual appraiser (stage 1 and 2)

QUALIFICATIONS:
1994 BSc (Hons) Molecular Biology, School of Life Sciences, University of Liverpool
1999 PhD Molecular Biology, Faculty of Medicine, University of Liverpool

Previous Positions

01/07/05-31/07/10 Lecturer
1/2/02-30/6/05 Senior Research Associate, University of Newcastle,
(Wellcome Trust funded, Level three, 1/2/02- 31/1/04; University of Newcastle funded, 2/2/05-30/6/05)
1/11/98-28/1/02 Research Associate, University of Newcastle (Action Research funded)

Memberships

2001- The Endocrine Society, USA
2002- The RNA Society, USA
2002- ASBMB (American Society for Biochemistry and Molecular Biology)
2002- FASEB (Federation of American Societies for Experimental Biology).
2007-European parturition Group-EuPG.
2008- Society for Gynecologic Investigation (SGI).

Undergraduate Teaching

PSC2015 Reproductive and Developmental Physiology (stage 2)-Module Leader
PSC3012 Integrated Physiology (stage 3)

• Sethna F, Tyson-Capper AJ, Shiells EA, Robson SC. The expression of glucocorticoid receptor in human myometrium in pregnancy and labour. J Steroids Hormon Sci 2011, 2.
• Tyson-Capper AJ, Shiells EA, Robson SC. Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors. Journal of Molecular Endocrinology 2009, 43(1), 29-41.
• Cork DMW, Lennard TWJ, Tyson-Capper AJ. Alternative splicing and the progresterone receptor in breast cancer. Breast Cancer Research 2008, 10(3), 207.
• Harper KA, Tyson-Capper AJ. Complexity of COX-2 gene regulation. Biochemical Society Transactions 2008, 36(3), 543-545.
• Tyson-Capper AJ. Alternative splicing: An important mechanism for myometrial gene regulation that can be manipulated to target specific genes associated with preterm labour. In: BMC Pregnancy and Childbirth: Proceedings of the First and Second European Workshops on Preterm Labour of the Special Non-Invasive Advances in Fetal and Neonatal Evaluation (SAFE) Network of Excellence. 2007, Tarragona, Spain: BioMed Central Ltd..
• Tyson-Capper AJ, Europe-Finner GN. Novel targeting of cyclooxygenase-2 (COX-2) pre-mRNA using antisense morpholino oligonucleotides directed to the 3′ acceptor and 5′ donor splice sites of exon 4: Suppression of COX-2 activity in human amnion-derived WISH and myometrial cells. Molecular Pharmacology 2006, 69(3), 796-804.
• Tyson-Capper AJ, Cork DMW, Wesley E, Shiells EA, Loughney AD. Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy. Molecular Human Reproduction 2006, 12(11), 695-701.
• Tyson-Capper AJ, Bailey J, Krainer AR, Robson SC, Europe-Finner GN. The switch in alternative splicing of cyclic AMP-response element modulator protein CREMτ2α (activator) to CREMα (repressor) in human myometrial cells is mediated by SRp40. Journal of Biological Chemistry 2005, 280(41), 34521-34529.
• Bailey J, Tyson-Capper AJ, Gilmore K, Robson SC, Europe-Finner GN. Identification of human myometrial target genes of the cAMP pathway: The role of cAMP-response element binding (CREB) and modulator (CREMα and CREMτ2α) proteins. Journal of Molecular Endocrinology 2005,34 1 1-17.
• Phillips RJ, Tyson-Capper AJ, Bailey J, Robson SC, Europe-Finner GN. Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: Involvement of specificity protein-1 (Sp1), Sp3,Sp4, Sp-like proteins, and histone deacetylases. Journal of Clinical Endocrinology and Metabolism 2005,90 6 3479-3490.
• Hong EEA, Elliot DJ, Tyson-Capper AJ. Effect of Oestrogen on RNA-Binding Splicing Regulators in Breast Cancer Cells. In: Reproductive Sciences: 57th Annual Meeting of the Society for Gynecologic Investigation. 2010, Orlando, Florida: Sage Publications, Inc.