Publication:

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases (2012)

Author(s): Hui W, Litherland GJ, Elias MS, Kitson GI, Cawston TE, Rowan AD, Young DA

      • Date: 09-11-2011
      • Journal: Annals of the Rheumatic Diseases
      • Volume: 71
      • Issue: 3
      • Pages: 455-462
      • Publisher: BMJ Group
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: HUMAN ARTICULAR CHONDROCYTES NECROSIS-FACTOR-ALPHA ONCOSTATIN-M COLLAGENASE EXPRESSION OSTEOARTHRITIC CARTILAGE THERAPEUTIC TARGETS KNEE OSTEOARTHRITIS SYNOVIAL-FLUID MESSENGER-RNA MURINE MODEL

      Staff

      Professor Tim Cawston
      Strategic Res Advisor (William Leech) and William Leech Professor of Rheumatology

      Professor Drew Rowan
      Professor of Molecular Rheumatology

      Dr David Young
      Senior Lecturer