Publication:

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases (2012)

Author(s): Hui W, Litherland GJ, Elias MS, Kitson GI, Cawston TE, Rowan AD, Young DA

      • Date: 09-11-2011
      • Journal: Annals of the Rheumatic Diseases
      • Volume: 71
      • Issue: 3
      • Pages: 455-462
      • Publisher: BMJ Group
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: HUMAN ARTICULAR CHONDROCYTES NECROSIS-FACTOR-ALPHA ONCOSTATIN-M COLLAGENASE EXPRESSION OSTEOARTHRITIC CARTILAGE THERAPEUTIC TARGETS KNEE OSTEOARTHRITIS SYNOVIAL-FLUID MESSENGER-RNA MURINE MODEL

      Staff

      Professor Tim Cawston
      Strategic Res Advisor (William Leech) and William Leech Professor of Rheumatology

      Professor Drew Rowan
      Professor of Molecular Rheumatology

      Professor David Young
      Professor of Musculoskeletal Biology