Bioinformatics Support Unit

Bioinformatics Support UnitThe Bioinformatics Support Unit provides data analysis and experimental design services for next-generation sequencing, microarrays, proteomics and more.

Services Offered

The Bioinformatics Support Unit has extensive expertise in making sense of the deluge of data from modern scientific studies. With core competencies in handling traditional 'omics datasets (genomic, transcriptomic and proteomic) the Unit is able to advise on all issues related to the capture, analysis and long-term storage of high-throughput experimental data.

We can help researchers using high throughput sequencing machines such as Illumina (MiSeq, HiSeq, GAIIx), Ion Torrent, Roche 454 or ABI SOLiD. Whether you are doing de novo sequencing of non-model organisms, comparative transcriptomics with RNA-Seq, ChIP-Seq for transcription factor binding or histone mark discovery, deep sequencing for polymorphism discovery or any other NGS application please get in touch about how we can help you.

The Unit provides extensive expertise in a range of software for data analysis, including BWA, Bowtie and other aligners for all NGS platforms and applications; Mira and Velvet for de novo assembly; Tophat, Cufflinks, DESeq and Trinity (among others) for RNA-Seq analysis; GATK for variant calling; MACS, SISSRs and other peak callers for ChIP-Seq analysis; and GeneSpring GX and BioConductor/R for microarray analysis.

Successfully applying bioinformatics to scientific research requires the involvement of an informatician at every step of the process. We are happy to advise on the likely informatics requirement of a project at the grant preparation stage, support your application as a named investigator, supply wording, costings and advice on experimental design and follow through to publication to ensure successful submissions.

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