NHS logoDental Clinical Research Facility


Dental Clinical Research FacilityThe Dental Clinical Research Facility (CRF) is a dedicated clinical research environment within the Newcastle School of Dental Sciences and Dental Hospital for conducting high quality clinical dental research.

Services Offered

Clinical Research Platform logoGood oral health is fundamental to good general health. Oral health research is therefore essential for improving health and wellbeing, and the Dental CRF has been developed to accommodate all strands of clinical dental research, including quantitative and qualitative research, clinical trials and translational research. The Dental CRF is the clinical research environment for the Centre for Oral Health Research at Newcastle University and is supported by the full infrastructure of the University and its Research Institutes.

The unit comprises 4 fully equipped dental surgeries in which all types of dental procedures can be undertaken. Two of the surgeries are equipped with operating microscopes for advanced surgical and restorative procedures.

A full range of clinical dental research can be undertaken, including restorative dentistry, endodontics, periodontics, implant research, dental materials research, paediatric dentistry, local anaesthetic studies, fluoride therapy, nutritional research, and surgical procedures.

The Dental CRF is supported by three fully equipped research laboratories including a dental materials research laboratory, a fluoride research laboratory, and an oral biology laboratory (immunology, cell biology and microbiology research). Clinical samples obtained from patients in the Dental CRF can be transported directly to these research laboratories which are all located in the School of Dental Sciences.

This facility and associated laboratories offer full processing and storage facilities for therapeutic materials and biological samples.

Portfolio research studies and clinical trials are prioritised, but also support for small scale, pump priming research. The CRF is staffed by appropriate research support staff, specifically dental nurses and dental hygienists and a research manager.

The Dental CRF is the perfect location for conducting translational clinical dental research and industry sponsored clinical trials.

Services offered include:

  • Clinical dental research
  • Qualitative research (quality of life)
  • Clinical trials (including devices, pharmacological and pharmaceutical studies)
  • Dental materials research
  • Fluoride analysis
  • Nutritional research
  • Acidogenicity and erosivity
  • Clinical evaluation of oral healthcare products
  • Restorative dentistry research
  • Local anaesthetics research
  • Implant research

Specialist Services include all types of dental procedures, operating microscopes and implant research. Laboratory facilities include:

  • Sample preparation,Tissue culture
  • Microbiology
  • Molecular analytical techniques
  • Fluoride analysis of biological and non-biological samples
  • Atomic force microscope
  • Confocal laser scanning microscopy

Further information:

  • Contact: Susan Bissett, Dental CRF Team Lead
  • E-mail: s.m.bissett@ncl.ac.uk
  • Telephone: +44 (0)191 282 1170
  • Contact: Professor Philip Preshaw, Director
  • E-mail: p.m.preshaw@ncl.ac.uk
  • Telephone: +44 (0)191 208 8193