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Errington Group: EMBO Journal Article

Nucleoid occlusion protein Noc recruits DNA to the bacterial cell membrane

 

David William Adams, Ling Juan Wu, Jeff Errington

published on: 19th March 2015

ICaMB excels in REF2014

published on: 19th March 2015

Korolchuk Group: New Publication in Molecular Cell

In Brief

PI(3)P, the product of VPS34, regulates canonical autophagy; however, mammalian cells can produce autophagosomes through enigmatic noncanonical VPS34-independent pathways. Vicinanza et al. show that PI(5) P can regulate autophagy, even in cells where VPS34 is compromised and acts via PI(3)P effectors. This provides a mechanistic explanation for forms of noncanonical autophagy.

published on: 2nd March 2015

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