Pinnacle would like to thank all those who have taken the trouble to recognise the efforts of this unit in supporting their research.
If you have a published paper that acknowledges the unit please let us know.
Cellular Iron Distribution in Bacillus anthracis.
Wang Yung Tu, Susanne Pohl, Joe Gray, Nigel Robinson, Colin Harwood, and Kevin Waldron.
J Bacteriol. 2012 Mar;194(5):932-40.
Low resolution structure and dynamics of a colicin-receptor complex determined by neutron scattering.
Clifton LA, Johnson CL, Solovyova AS, Callow P, Weiss KL, Ridley H, Le Brun AP, Kinane CJ, Webster JR, Holt SA, Lakey JH.
J Biol Chem. 2012 Jan 2;287(1):337-46.
Peptidoglycan-Modifying Enzyme Pgp1 Is Required for Helical Cell Shape and Pathogenicity Traits in Campylobacter jejuni.
Frirdich E, Biboy J, Adams C, Lee J, Ellermeier J, Gielda LD, Dirita VJ, Girardin SE, Vollmer W, Gaynor EC.
PLoS Pathog. 2012 Mar;8(3):e1002602.
Identification of genetic determinants and enzymes involved with the amidation of glutamic acid residues in the peptidoglycan of Staphylococcus aureus.
Figueiredo TA, Sobral RG, Ludovice AM, Almeida JM, Bui NK, Vollmer W, Lencastre H, Tomasz A.
PLoS Pathog. 2012 Jan;8(1):e1002508.
Isolation and analysis of cell wall components from Streptococcus pneumoniae.
Bui NK, Eberhardt A, Vollmer D, Kern T, Bougault C, Tomasz A, Simorre JP, Vollmer W.
Anal Biochem. 2012 Feb 15;421(2):657-66.
Flagellin redundancy in Caulobacter crescentus and its implications for flagellar filament assembly.
Faulds-Pain A, Birchall C, Aldridge C, Smith WD, Grimaldi G, Nakamura S, Miyata T, Gray J, Li G, Tang JX, Namba K, Minamino T, Aldridge PD.
J. Bacteriol. 2011 Jun;193(11):2695-707.
Type VI secretion delivers bacteriolytic effectors to target cells.
Russell AB, Hood RD, Bui NK, LeRoux M, Vollmer W, Mougous JD. 2011.
Nature 475, 343-347.
Copper-Binding Properties and Structures of Methanobactins from Methylosinus trichosporium OB3b.
El Ghazouani A, Basle A, Firbank SJ, Knapp CW, Gray J, Graham DW, Dennison C.
Inorganic Chemistry 2011, 50(4), 1378-1391.
Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin E.
Karavolos MH, Bulmer D, Spencer H, Rampioni G, Schmalen I, Baker S, Pickard D, Gray J, Fookes M, Winzer K, Ivens A, Dougan G, Williams P, Khan CMA.
EMBO Reports 2011, 12(3), 252-258.
RNase Y in Bacillus subtilis: a natively disordered protein that is the functional equivalent to RNase E from Escherichia coli.
Martin Lehnik-Habrink, Joseph Newman, Fabian Rothe, Alexandra Solovyova, Cecilia Rodrigues, Christina Herzberg, Fabian Commichau, Richard Lewis, Jorg Stulke.
J Bacteriol. 2011 Oct;193(19):5431-41.
A novel in vivo cell wall labeling approach sheds new light on peptidoglycan synthesis in Escherichia coli.
Olrichs NK, Aarsman MEG, Arnusch CJ, Vollmer W, de Kruijff B, Breukink E, den Blaauwen T. 2011.
ChemBioChem 12, 1124-1133.
Crystallization and preliminary X-ray analysis of the bacillaene synthase trans-acting acyltransferase PksC.
Cuskin F., Solovyova AS, Lewis RJ, Race PR.
Acta Crystallogr. Sect.F, Struct.Biol.Cryst. Commun. 2011 67:464-6.
The transcription repressor NmrA is subject to proteolysis by three Aspergillus nidulans proteases.
Zhao X, Hume SL, Johnson C, Thompson P, Huang J, Gray J, Lamb HK, Hawkins AR.
Protein Science. 2010 Jul;19(7):1405-19.
Roles of minor pilin subunits Spy0125 and Spy0130 in the serotype M1 Streptococcus pyogenes strain SF370.
Smith WD, Pointon JA, Abbot E, Kang HJ, Baker EN, Hirst BH, Wilson JA, Banfield MJ, Kehoe MA.
J Bacteriol. 2010 Sep;192(18):4651-9.
Ceramide is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease.
Brodlie M, McKean MC, Johnson GE, Gray J, Fisher AJ, Corris PA, Lordan JL, Ward C.
Am J Respir Crit Care Med. 2010 Aug 1;182(3):369-75.
Salmonella pathogenicity island 1 (SPI-1) type III secretion of SopD involves N- and C-terminal signals and direct binding to the InvC ATPase.
Boonyom R, Karavolos MH, Bulmer DM, Khan CM.
Microbiology. 2010 Jun;156(6):1805-14.
Identification of potential HLA class I and class II epitope precursors associated with heat shock protein 70 (HSPA).
Stocki P, Morris NJ, Preisinger C, Wang XN, Kolch W, Multhoff G, Dickinson AM.
Cell Stress Chaperones. 2010 Sep;15(5):729-41.
MreB drives de novo rod morphogenesis in Caulobacter crescentus via remodeling of the cell wall.
Takacs CN, Poggio S, Charbon G, Pucheault M, Vollmer W, Jacobs-Wagner C.
J Bacteriol. 2010 Mar;192(6):1671-84.
Glycine transporter GLYT1 is essential for glycine-mediated protection of human intestinal epithelial cells against oxidative damage.
Howard A, Tahir I, Javed S, Waring SM, Ford D, Hirst BH.
J Physiol. 2010 Mar 15;588(Pt 6):995-1009.
Genome-wide transposon mutagenesis identifies a role for host neuroendocrine stress hormones in regulating the expression of virulence genes in Salmonella.
Spencer H, Karavolos MH, Bulmer DM, Aldridge P, Chhabra SR, Winzer K, Williams P, Khan CM.
J Bacteriol. 2010 Feb;192(3):714-24.
The interaction dynamics of a negative feedback loop regulates flagellar number in Salmonella enterica serovar Typhimurium.
Aldridge C, Poonchareon K, Saini S, Ewen T, Solovyova A, Rao CV, Imada K, Minamino T, Aldridge PD.
Molecular Microbiology 2010 78 (6): 1416-1430.
A novel acid-stable, acid-active beta-galactosidase potentially suited to the alleviation of lactose intolerance.
O'Connell S, Walsh G.
Appl Microbiol Biotechnol. 2010 Mar;86(2): 517-24.
A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease.
Gray J, Chattopadhyay D, Beale GS, Patman GL, Miele L, King BP, Stewart S, Hudson M, Day CP, Manas DM, Reeves HL.
BMC Cancer. 2009 Aug 5;9: 271.
The peptidoglycan sacculus of Myxococcus xanthus has unusual structural features and is degraded during glycerol-induced myxospore development.
Bui NK, Gray J, Schwarz H, Schumann P, Blanot D, Vollmer W.
J Bacteriol. 2009 Jan;191(2):494-505.
Crystal structures of Cif from bacterial pathogens Photorhabdus luminescens and Burkholderia pseudomallei.
Crow A, Race PR, Jubelin G, Varela Chavez C, Escoubas JM, Oswald E, Banfield MJ.
PLoS One. 2009;4(5):e5582.
Fine mapping of interactions between eEF1alpha protein and 3'UTR of metallothionein-1 mRNA.
Fan K, Chrzanowska-Lightowlers ZM, Hesketh JE.
Biochem Biophys Res Commun. 2009 Aug 14;386(1):82-8.
Physical and functional interactions between Escherichia coli MutL and the Vsr repair endonuclease.
R. Heinze, L. Giron-Monzon, A.S. Solovyova, S.L. Elliot, S. Geisler, C.G. Cupples, B.A. Connolly, P. Friedhoff
Nucleic Acid Res 2009 37:4453-63.
Characterization of the immune response of domestic fowl following immunization with proteins extracted from Dermanyssus gallinae.
Harrington D, Din HM, Guy J, Robinson K, Sparagano O.
Vet Parasitol. 2009 Mar 23;160(3-4):285-94.
Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism.
Race PR, Bentley ML, Melvin JA, Crow A, Hughes RK, Smith WD, Sessions RB, Kehoe MA, McCafferty DG, Banfield MJ.
J Biol Chem. 2009 Mar 13;284(11):6924-33.
Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae.
Baur S, Marles-Wright J, Buckenmaier S, Lewis RJ, Vollmer W.
J Bacteriol. 2009 Feb;191(4):1200-10.
Solution structure of the major (Spy0128) and minor (Spy0125 and Spy0130) pili subunits from Streptococcus pyogenes.
A.S. Solovyova J.A. Pointon, P.R. Race, W.D. Smith, M.A. Kehoe, M.J. Banfield
Eur. Biophys. J. 2009 39: 469-80.
Characterization of the immune response of domestic fowl following immunization with proteins extracted from Dermanyssus gallinae.
Harrington D, Din HM, Guy J, Robinson K, Sparagano O.
Vet Parasitol. 2009 Mar 23;160(3-4):285-94.
Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae.
Baur S, Marles-Wright J, Buckenmaier S, Lewis RJ, Vollmer W.
J Bacteriol. 2009 Feb;191(4):1200-10.
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups.
Sulong S, Moorman AV, Irving JA, Strefford JC, Konn ZJ, Case MC, Minto L, Barber KE, Parker H, Wright SL, Stewart AR, Bailey S, Bown NP, Hall AG, Harrison CJ.
Blood. 2009 Jan 1;113(1):100-107.
Protein-folding location can regulate manganese-binding versus copper- or zinc-binding.
Tottey S, Waldron KJ, Firbank SJ, Reale B, Bessant C, Sato K, Cheek TR, Gray J, Banfield MJ, Dennison C, Robinson NJ.
Nature. 2008 Oct 23;455(7216):1138-42.
AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease.
Beale G, Chattopadhyay D, Gray J, Stewart S, Hudson M, Day C, Trerotoli P, Giannelli G, Manas D, Reeves H.
BMC Cancer. 2008 Jul 18;8:200.
Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway.
Walden HR, Kirby JA, Yeaman SJ, Gray J, Jones DE, Palmer JM.
Hepatology. 2008 Dec;48(6):1874-84.
Site-specific release of nascent chains from ribosomes at a sense codon.
Doronina VA, Wu C, de Felipe P, Sachs MS, Ryan MD, Brown JD.
Mol Cell Biol. 2008 Jul;28(13):4227-39.
Characterization of hepatitis C RNA-containing particles from human liver by density and size.
Nielsen SU, Bassendine MF, Martin C, Lowther D, Purcell PJ, King BJ, Neely D, Toms GL.
J Gen Virol. 2008 Oct;89(Pt 10):2507-17.
Adrenaline modulates the global transcriptional profile of Salmonella revealing a role in the antimicrobial peptide and oxidative stress resistance responses.
Karavolos MH, Spencer H, Bulmer DM, Thompson A, Winzer K, Williams P, Hinton JC, Khan CM.
BMC Genomics. 2008 Oct 6;9:458.
Significant contribution of the pgdA gene to the virulence of Streptococcus suis.
Fittipaldi N, Sekizaki T, Takamatsu D, Domínguez-Punaro Mde L, Harel J, Bui NK, Vollmer W, Gottschalk M.
Mol Microbiol. 2008 Dec;70(5):1120-35.
Application relevant studies of fungal beta-galactosidases with potential application in the alleviation of lactose intolerance.
O'Connell S, Walsh G.
Appl Biochem Biotechnol. 2008 May;149(2):129-38.
Interplay between DNA polymerase and proliferating cell nuclear antigen switches off base excision repair of uracil and hypoxanthine during replication in archaea .
K. Emptage, R. O’Neil, A.S. Solovyova, B.A. Connolly
J. Mol. Biol. 2008 383: 762-71.
Nichols CE, Lamb HK, Lockyer M, Charles IG, Pyne S, Hawkins AR, Stammers DK.
Characterization of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases.
Proteins. 2007 Jul 1;68(1):13-25.
Waldron KJ, Tottey S, Yanagisawa S, Dennison C, Robinson NJ.
A periplasmic iron-binding protein contributes toward inward copper supply.
J Biol Chem. 2007 Feb 9;282(6):3837-46.
van Nues RW, Brown JD.
Distant segments of Saccharomyces cerevisiae scR1 RNA promote assembly and function of the signal recognition particle.
J Mol Biol. 2007 May 4;368(3):677-90.
Lamb HK, Thompson P, Elliott C, Charles IG, Richards J, Lockyer M, Watkins N, Nichols C, Stammers DK, Bagshaw CR, Cooper A, Hawkins AR.
Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium.
Protein Sci. 2007 Nov;16(11):2391-402.
Banci L, Bertini I, Cantini F, Ciofi-Baffoni S, Cavet JS, Dennison C, Graham AI, Harvie DR, Robinson NJ.
NMR structural analysis of cadmium sensing by winged helix repressor CmtR.
J Biol Chem. 2007 Oct 12;282(41):30181-8.
Conformation of the EPEC Tir protein in solution: the impact of serine phosphorylation at positions 434/463.
P.R. Race, A. S. Solovyova, M.J Banfield
Biophys. J. 2007 93: 586-596.
Selection of mimotopes of Bovine Viral Diarrhoea Virus using a solid-phase peptide library.
Kalaycioglu AT, Russell PH, Howard CR.
Vaccine. 2007 Oct 10;25(41):7081-6.
Production, purification and application-relevant characterisation of an endo-1,3(4)-beta-glucanase from Rhizomucor miehei.
Boyce A, Walsh G.
Appl Microbiol Biotechnol. 2007 Sep;76(4):835-41.
Purification and properties of a beta-galactosidase with potential application as a digestive supplement.
O'Connell S, Walsh G.
Appl Biochem Biotechnol. 2007 Apr;141(1):1-14.
Purification and characterisation of an acid phosphatase with phytase activity from Mucor hiemalis Wehmer.
Boyce A, Walsh G.
J Biotechnol. 2007 Oct 15;132(1):82-7.
Chalton DA, Musson JA, Flick-Smith H, Walker N, McGregor A, Lamb HK, Williamson ED, Miller J, Robinson JH, Lakey JH.
Immunogenicity of a Yersinia pestis vaccine antigen monomerized by circular permutation.
Infect Immun. 2006 Dec;74(12):6624-31.
Musson JA, Morton M, Walker N, Harper HM, McNeill HV, Williamson ED, Robinson JH.
Sequential proteolytic processing of the capsular Caf1 antigen of Yersinia pestis for major histocompatibility complex class II-restricted presentation to T lymphocytes.
J Biol Chem. 2006 Sep 8;281(36):26129-35
Greenall A, Williams ES, Martin KA, Palmer JM, Gray J, Liu C, Whitehall SK.
Hip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation.
J Biol Chem. 2006 Mar 31;281(13):8732-9.
Delumeau O, Chen CC, Murray JW, Yudkin MD, Lewis RJ.
High-molecular-weight complexes of RsbR and paralogues in the environmental signaling pathway of Bacillus subtilis.
J Bacteriol. 2006 Nov;188(22):7885-92.
Shim HK, Musson JA, Harper HM, McNeill HV, Walker N, Flick-Smith H, von Delwig A, Williamson ED, Robinson JH.
Mechanisms of major histocompatibility complex class II-restricted processing and presentation of the V antigen of Yersinia pestis.
Immunology. 2006 Nov;119(3):385-92.
Keresztessy Z, Csosz E, Hársfalvi J, Csomós K, Gray J, Lightowlers RN, Lakey JH, Balajthy Z, Fésüs L.
Phage display selection of efficient glutamine-donor substrate peptides for transglutaminase 2.
Protein Sci. 2006 Nov;15(11):2466-80.
von Delwig A, Musson JA, Gray J, McKie N, Robinson JH.
Major histocompatibility class II molecules prevent destructive processing of exogenous peptides at the cell surface of macrophages for presentation to CD4 T cells.
Immunology. 2006 Feb;114(2):194-203.
Lind T, Birch MA, McKie N.
Purification of an insect derived recombinant human ADAMTS-1 reveals novel gelatin (type I collagen) degrading activities.
Mol Cell Biochem. 2006 Jan;281(1-2):95-102.
Race PR, Lakey JH, Banfield MJ.
Insertion of the enteropathogenic Escherichia coli Tir virulence protein into membranes in vitro.
J Biol Chem. 2006 Mar 24;281(12):7842-9.
Mickleburgh I, Chabanon H, Nury D, Fan K, Burtle B, Chrzanowska-Lightowlers Z, Hesketh J.
Elongation factor 1alpha binds to the region of the metallothionein-1 mRNA implicated in perinuclear localization--importance of an internal stem-loop.
RNA. 2006 Jul;12(7):1397-407.
