ICAMB Ageing Research
Work on ageing in the Institute involves looking at how our gut bacteria alter with age, what consequences this may have for healthy ageing and how sunlight, inflammation and oxygen cause stress in ageing cells and affect telomeres, structures in chromosomes that protect against ageing. We have a deep interest in essential trace metals and are studying how ageing cells handle copper, one of these metals.
The staff listed below are involved in age-related research in the following areas:
- Prof Dave Lydall - human genetic defects in DNA-damage responses which lead to diseases associated with ageing and cancer. DNA damage/repair and telomere maintenance in ageing cells.
- Dr Liz Veal and Prof Brian Morgan - exposure to sunlight, immune cell attack and aerobic metabolism generate highly toxic chemicals and the impact of this causing stress in ageing cells.
- Prof Harry Gilbert and Dr Dave Bolam - comparative analysis of the microbiome in individuals as they age.
- Dr Julian Rutherford -
copper proteome in ageing cells.
