Newcastle University

Publication:

Differential selection of acridine resistance mutations in human DNA topoisomerase II beta is dependent on the acridine structure (2007)

Author(s): Leontiou C, Watters GP, Gilroy KL, Heslop P, Cowell IG, Craig K, Lightowlers RN, Lakey JH, Austin CA

• Date: 01-04-2007
• Journal: Molecular Pharmacology
• Volume: 71
• Issue: 4
• Pages: 1006-1014
• Publisher: American Society for Pharmacology and Experimental Therapeutics
• Publication type: Article
• Bibliographic status: Published

• URL: http://dx.doi.org/10.1124/mol.106.032953
• DOI: 10.1124/mol.106.032953
• ISSN (electronic): 1521-0111

Keywords: METAL-ION MECHANISM NON-CYCLING CELLS CLEAVABLE COMPLEXES DRUG-RESISTANCE POINT MUTATION AMSACRINE ALPHA LEUKEMIA ANTITUMOR DOMAIN

Staff

Professor Caroline Austin Professor of Molecular Biology	Email: caroline.austin@ncl.ac.uk Telephone: +44 (0) 191 222 8864
Dr Ian Cowell Team Scientist	Email: ian.cowell@ncl.ac.uk Telephone: +44 (0) 191 222 7677
Professor Jeremy Lakey Professor of Structural Biochemistry	Email: jeremy.lakey@ncl.ac.uk Telephone: +44 (0) 191 222 8865
Professor Robert Lightowlers Director, ICaMB and Professor of Molecular Neuroscience	Email: robert.lightowlers@ncl.ac.uk Telephone: +44 (0) 191 222 8028