Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation (2009)

Author(s): Kirby DM, Rennie KJ, Smulders-Srinivasan TK, Acin-Perez R, Whittington M, Enriquez JA, Trevelyan AJ, Turnbull DM, Lightowlers RN

      • Date: 23-06-2009
      • Journal: Cell Proliferation
      • Volume: 42
      • Issue: 4
      • Pages: 413-424
      • Publisher: Wiley-Blackwell Publishing Ltd.
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: Mouse mitochondrial DNA Motor nerve terminals Complex I ES cells Disease Mice CA2+ Release Inhibition Generation


      Professor Robert Lightowlers
      Director, ICaMB and Professor of Molecular Neuroscience