Publication:
Self-Organisation of Self-Complementary DNA Molecules Covalently Attached to Silicon Surfaces (2011)
Author(s): Carlsson S, Gonzalez R, OFarrell N, Patole SN, Connolly BA, Houlton A, Horrocks BR, Pike A
Abstract: Self-complementary oligonucleotides were synthesized at atomically-flat Si(111) surfaces and their hybridization reaction was studied using atomic force microscopy. Annealing these surfaces in aqueous media, in the absence of any other reagents or DNA, resulted in a self-organization process in which hybridization produced well-defined features in the AFM images. By varying the surface coverage of DNA we provide evidence that the features observed are due to inter-strand rather than intra-strand hybridization reactions.
- Date: 01-06-2011
- Journal: Science of Advanced Materials
- Volume: 3
- Issue: 3
- Pages: 483-489
- Publisher: American Scientific Publishers
- Publication type: Article
- Bibliographic status: Published
- URL: http://dx.doi.org/10.1166/sam.2011.1164
- DOI: 10.1166/sam.2011.1164
- ISSN (electronic): 1947-2943
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Professor Bernard Connolly
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Dr Ben Horrocks
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Professor Andrew Houlton
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