Newcastle University

Publications

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• De Soyza A, Ellis CD, Khan CMA, Corris P, Demarco de Hormaeche R. Burkholderia Cenocepacia Lipopolysaccharide, Lipid A and Proinflammatory Activity. American Journal of Respiratory and Critical Care Medicine 2004, 170(1), 70-77.
• van Nues RW, Brown JD. Saccharomyces SRP RNA secondary structures: A conserved S-domain and extended Alu-domain. RNA 2004, 10(1), 75-89.
• Hrdy I, Hirt RP, Dolezal P, Bardonova L, Foster PG, Tachezy J, Embley TM. Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I. Nature 2004, 432(7017), 618-622.
• Veal EA, Findlay VJ, Day AM, Bozonet SM, Evans JM, Quinn J, Morgan BA. A 2-Cys peroxiredoxin regulates peroxide-induced oxidation and activation of a stress-activated MAP kinase. Molecular Cell 2004, 15(1), 129-139.
• Smith DA, Nicholls S, Morgan BA, Brown AJP, Quinn J. A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans. Molecular Biology of the Cell 2004, 15(9), 4179-4190.
• Pinho MG, Errington J. A divIVA null mutant of Staphylococcus aureus undergoes normal cell division. FEMS Microbiology Letters 2004, 240(2), 145-149.
• Blankley RT, Lydall D. A domain of Rad9 specifically required for activation of Chk1 in budding yeast. Journal of Cell Science 2004, 117(4), 601-608.
• Sun Y, Wipat A, Pocock M, Lee P, Watson P, Flanagan K, Worthington J. A Grid-based System for Microbial Genome Comparison and Analysis. Newcastle upon Tyne: School of Computing Science, University of Newcastle upon Tyne, 2004. School of Computing Science Technical Report Series 881.
• Anderluh G, Gokce I, Lakey JH. A Natively Unfolded Toxin Domain Uses Its Receptor as a Folding Template. Journal of Biological Chemistry 2004, 279(21), 22002-22009.
• Rakonczay Z, Fearn A, Feber EA, Hegyi P, Gray MA, Argent BE. A novel basolateral bicarbonate transport mechanism in human pancreatic duct cells. In: 36th European Pancreatic Club Meeting. 2004, Padova, Italy.
• Willmore, E., De Caux, S., Sunter, N., Tilby, M.J., Jackson, G., Austin, C., Durkacz, B.W. A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. Blood 2004, 103(12), 4659-4665.
• Maniura-Weber K, Taylor RW, Johnson MA, Chrzanowska-Lightowlers Z, Morris AAM, Charlton CPJ, Turnbull DM, Bindoff LA. A novel point mutation in the mitochondrial tRNA(Trp) gene produces a neurogastrointestinal syndrome. European Journal of Human Genetics 2004, 12(6), 509-512.
• Rovio AT, Abel J, Ahola AL, Andres AM, Bertranpetit J, Blancher A, Bontrop RE, Chemnick LG, Cooke HJ, Cummins JM, Davis HA, Elliott DJ, Fritsche E, Hargreave TB, Hoffman SMG, Jequier AM, Kao S-H, Kim H-S, Marchington DR, Mehmet D, Otting N, Poulton J, Ryder OA, Schuppe H-C, Takenaka O, Wei Y-H, Wichmann L, Jacobs HT. A prevalent POLG CAG microsatellite length allele in humans and African great apes. Mammalian Genome 2004, 15(6), 492-502.
• Harrison MD, Dennison C. An axial met ligand at a type 1 copper site is preferable for fast electron transfer. ChemBioChem 2004, 5(11), 1579-1581.
• Horner DS, Hirt RP. An overview on eukaryote origins and evolution: the beauty of the cell and the fabulous gene phylogenies. In: R. P. Hirt;D. S. Horner, ed. Organelles, Genomes and Eukaryote Phylogeny: An Evolutionary Synthesis in the Age of Genomics. Boca Raton, USA: CRC Press, 2004, pp.1-23.
• Ball SL, Siou GP, Howard A, Hall J, Wilson JA, Hirst BH. Antimicrobial peptide expression in human tonsils. Clinical Otolaryngology & Allied Sciences 2004, 29(4), 427.
• Shaw O, Koelmans A, Steggles J, Wipat A. Applying Petri Nets to Systems Biology using XML Technologies. Newcastle upon Tyne: School of Computing Science, University of Newcastle upon Tyne, 2004. School of Computing Science Technical Report Series 827.
• Shaw O, Koelmans A, Steggles J, Wipat A. Applying Petri Nets to Systems Biology using XMLTechnologies. In: Workshop on the Definition, Implementation and Application of a Standard Interchange Format for Petri Nets. Satellite event of ATPN : 25th International Conference on Application and Theory of Petri Nets. 2004, Bologna, Italy.
• Watkins NJ, Lemm I, Ingelfinger D, Schneider C, Hoßbach M, Urlaub H, Lührmann R. Assembly and Maturation of the U3 snoRNP in the Nucleoplasm in a Large Dynamic Multiprotein Complex. Molecular Cell 2004, 16(5), 789-798.
• Netherwood T, Martin-Orue SM, O'Donnell AG, Gockling S, Graham J, Mathers JC, Gilbert HJ. Assessing the survival of transgenic plant DNA in the human gastrointestinal tract. Nature Biotechnology 2004, 22(2), 204-209.
• Li P, Hayward K, Jennings C, Owen K, Oinn T, Stevens R, Pearce S, Wipat A. Association of variations in I kappa B-epsilon with Graves’ disease using classical and myGrid methodologies. In: 2004 UK e-Science All Hands Meeting. 2004, Nottingham, UK: Engineering and Physical Sciences Research Council.
• Hallinan J, Wiles J. Asynchronous dynamics of an artificial genetic regulatory network. In: Artificial Life IX: Proceedings of the Ninth International Conference on the Simulation and Synthesis of Living Systems. 2004, Boston, Massachusetts, USA: MIT Press.
• Ebersbach G, Gerdes K. Bacterial mitosis: partitioning protein ParA oscillates in spiral-shaped structures and positions plasmids at mid-cell. Molecular Microbiology 2004, 52(2), 385-398.
• Gerdes K, Møller-Jensen J, Ebersbach G, Kruse T, Nordström K. Bacterial Mitotic Machineries. Cell 2004, 116(3), 359-366.
• Feltis BN, Reid DW, Ward C, Walters EH. BAL eotaxin and IL-5 in asthma, and the effects of inhaled corticosteroid and beta2 agonist. Respirology 2004, 9(4), 507-13.
• Gray MA. Bicarbonate secretion: It takes two to tango. Nature Cell Biology 2004, 6(4), 292-294.
• Park A, Lamb HK, Nichols C, Moore JD, Brown KA, Cooper A, Charles IG, Stammers DK, Hawkins AR. Biophysical and kinetic analysis of wild-type and site-directed mutants of the isolated and native dehydroquinate synthase domain of the AROM protein. Protein Science 2004, 13(8), 2108-2119.
• Hyslop LA, Nixon VL, Levasseur M, Chapman F, Chiba K, McDougall A, Venables JP, Elliott DJ, Jones KT. Ca²⁺-promoted cyclin B1 degradation in mouse oocytes requires the establishment of a metaphase arrest. Developmental Biology 2004, 269(1), 206-219.
• Whitaker M. Calcium imaging. In: Charles A. Ettensohn, Gregory A. Wray, and Gary M. Wessel, ed. Development of Sea Urchins, Ascidians, and Other Invertebrate Deuterostomes: Experimental Approaches. London: Elsevier Academic Press, 2004, pp.443-468.
• Sayer JA, Carr G, Simmons NL. Calcium phosphate and calcium oxalate crystal handling is dependent upon CLC-5 expression in mouse collecting duct cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2004, 1689(1), 83-90.
• Boraston A, Bolam DN, Gilbert HJ, Davies G. Carbohydrate-binding modules: Fine-tuning polysaccharide recognition. Biochemical Journal 2004, 382(3), 769-781.
• Hoischen C, Bolshoy A, Gerdes K, Diekmann S. Centromere parC of plasmid R1 is curved. Nucleic Acids Research 2004, 32(19), 5907-5915.
• Aldibbiat K, Scougall KT, Campbell SC, Macfarlane WM, Shaw J. Characterisation of pancreatic acinar cells for endocrine potential and determination of proinsulin processing and secretion following transfection with a human preproinsulin gene. In: Journal of Gene Medicine: 1st Annual Conference of the British Society for Gene Therapy. 2004, Oxford, UK: John Wiley & Sons, Inc.
• Harrison MD, Dennison C. Characterization of Arabidopsis thaliana Stellacyanin: A Comparison with Umecyanin. Proteins: Structure, Function and Genetics 2004, 55(2), 426-435.
• Nielsen SU, Bassendine MF, Burt AD, Bevitt DJ, Toms GL. Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver. Journal of General Virology 2004, 85(6), 1497-1507.
• Ward C, Headland L, Vest S, Brownlee IA, Forrest IA, Ward TA, Pritchard G, Murphy DM, Pearson JP, Dark J, Corris P. Clinically silent gastric aspiration is common in lung allografts. In: Winter Meeting of the British Thoracic Society. 2004, London: Thorax: BMJ Publishing Group.
• Hallinan JS. Cluster analysis of the p53 genetic regulatory network: Topology and biology. In: IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB). 2004, La Jolla, California, USA: IEEE.
• Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Love-Gregory LD, Permutt MA, Hattersley AT, Frayling TM. Common variants of the hepatocyte nuclear factor-4α P2 promoter are associated with type 2 diabetes in the U.K. population. Diabetes 2004, 53(11), 3002-3006.
• Nichols CE, Ren J, Leslie K, Dhaliwal B, Lockyer M, Charles I, Hawkins AR, Stammers DK. Comparison of ligand-induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases. Journal of Molecular Biology 2004, 343(3), 533-546.
• Wu LJ, Errington J. Coordination of Cell Division and Chromosome Segregation by a Nucleoid Occlusion Protein in Bacillus subtilis. Cell 2004, 117(7), 915-925.
• Ye J, van den Berg B. Crystal structure of the bacterial nucleoside transporter Tsx. EMBO Journal 2004, 23(16), 3187-3195.
• van den Berg B, Black PN, Clemons WM Jr, Rapoport TA. Crystal structure of the long-chain fatty acid transporter FadL. Science 2004, 304(5676), 1506-1509.
• Nichols CE, Lockyer M, Hawkins AR, Stammers DK. Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments. Proteins: Structure, Function and Genetics 2004, 56(3), 625-628.
• Dhaliwal B, Nichols CE, Ren J, Lockyer M, Charles I, Hawkins AR, Stammers DK. Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase. FEBS Letters 2004, 574(1-3), 49-54.
• McIntyre EA, Halse R, Yeaman SJ, Walker M. Cultured muscle cells from insulin-resistant type 2 diabetes patients have impaired insulin, but normal 5-amino-4-imidazolecarboxamide riboside-stimulated, glucose uptake. Journal of Clinical Endocrinology and Metabolism 2004, 89(7), 3440-3448.
• Chang HY, Levasseur M, Jones KT. Degradation of APC^cdc20 and APC^cdh1 substrates during the second meiotic division in mouse eggs. Journal of Cell Science 2004, 117(26), 6289-6296.
• Christensen S, Gerdes K. Delayed-relaxed-response explained by hyperactivation of RelE. Molecular Microbiology 2004, 53(2), 587-597.
• Oinn T, Addis M J, Ferris J, Marvin DJ, Greenwood M, Goble C, Wipat A, Li P, Carver T. Delivering Web service coordination capability to users. In: 13th World Wide Web Conference (WWW2004). 2004, New York, USA: ACM.
• Wipat A, Sun Y, Pocock M, Lee P, Watson P, Flanagan K. Developing Grid-based Systems for Microbial Genome. In: UK e-Science All Hands Meeting 2004. 2004, Nottingham UK: EPSRC.
• Errington, F., Willmore, E., Leontiou, C., Tilby, M., Austin, C. Differences in the longevity of topo IIα and topo IIβ drug-stabilized cleavable complexes and the relationship to drug sensitivity. Cancer Chemotherapy and Pharmacology 2004, 53(2), 155-162.
• Lindner C, Nijland R, van Hartskamp M, Bron S, Hamoen LW, Kuipers OP. Differential expression of two paralogous genes of Bacillus subtilis encoding single-stranded DNA binding protein. Journal of Bacteriology 2004, 186(4), 1097-1105.
• Prime-Chapman HM, Fearn RA, Cooper AE, Moore V, Hirst BH. Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. Journal of Pharmacology and Experimental Therapeutics 2004, 311(2), 476-484.
• Moore I, Ahmed S, Sayer JA, Ward MK. Digital ischaemia in a renal transplant patient. Nephrology Dialysis Transplantation 2004, 19(6), 1656-1657.
• Muchová K, Lewis RJ, Perečko D, Brannigan JA, Ladds JC, Leech A, Wilkinson AJ, Barák I. Dimer-induced signal progation in Spo0A. Molecular Microbiology 2004, 53(3), 829-842.
• Dong TC, Cutting SM, Lewis RJ. DNA-binding studies on the Bacillus subtilis transcriptional regulator and AbrB homologue, SpoVT. FEMS Microbiology Letters 2004, 233(2), 247-256.
• Moller-Jensen J, Gerdes K. Dynamic instability of a bacterial engine. Science 2004, 306(5698), 987-989.
• Forrest IA, Murphy D, Lordan JL, Pritchard GE, Jones D, Robertson H, Cawston TE, Dark JH, Kirby JA, Corris PA, Ward C. Epithelial to mesenchymal transition in clinically stable lung transplantation. In: Winter Meeting of the British Thoracic Society. 2004, London: Thorax: BMJ Publishing Group.
• Ratanamart J, Scougall KT, Kirby JA, Shaw JAM. Establishment of an in vitro bioassay for immunogenicity of bacterial lipopolysaccharide and unmethylated CpG motifs in plasmid-derived gene therapy vectors. In: Journal of Gene Medicine: 1st Annual Conference of the British Society for Gene Therapy. 2004, Oxford, UK: John Wiley & Sons, Inc.
• Hallinan J, Wiles J. Evolving genetic regulatory networks using an artificial genome. In: Bioinformatics: Second Asia-Pacific Bioinformatics Conference (APBC). 2004, Dunedin, New Zealand: Australian Computer Society Inc.
• Zubko MK, Guillard S, Lydall D. Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics 2004, 168(1), 103-115.
• Maringele L, Lydall D. EXO1 Plays a Role in Generating Type I and Type II Survivors in Budding Yeast. Genetics 2004, 166(4), 1641-1649.
• Paleri V, Pearson JP, Bulmer D, Jeannon JP, Wight RG, Wilson JA. Expression of much gene products in laryngeal squamous cancer. Otolaryngology - Head and Neck Surgery 2004, 131(1), 84-88.
• Delumeau O, Dutta S, Brigulla M, Kuhnke G, Hardwick SW, Völker U, Yudkin MD, Lewis RJ. Functional and Structural Characterization of RsbU, a Stress Signaling Phosphatase 2C. Journal of Biological Chemistry 2004, 279(39), 40927-40937.
• Chrzanowska-Lightowlers ZMA, Temperley RJ, Smith PM, Seneca SH, Lightowlers RN. Functional polypeptides can be synthesized from human mitochondrial transcripts lacking termination codons. Biochemical Journal 2004, 377(3), 725-731.
• Hallinan J. Gene duplication and hierarchical modularity in intracellular interaction networks. BioSystems 2004, 74(1-3), 51-62.
• Campbell RN, Shaw JAM, Macfarlane WM. Generation of glucose-responsive insulin expression constructs for use in a muscle-targeted gene therapy approach to the treatment of diabetes mellitus. In: Journal of Gene Medicine: 1st Annual Conference of the British Society for Gene Therapy. 2004, Oxford, UK: John Wiley & Sons, Inc.
• Evans L, Feucht A, Errington J. Genetic analysis of the Bacillus subtilis sigG promoter, which controls the sporulation-specific transcription factor σG. Microbiology 2004, 150(7), 2277.
• Baerends RJ, Smits WK, de Jong A, Hamoen LW, Kok J, Kuipers OP. Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data. Genome Biology 2004, 5(5), R37.
• Forrest IA, Platt RE, Nicholson L, Pritchard G, Murphy D, Ward C, Corris PA, Middleton PG. Genotypic risk factors for the development of the bronchiolitis oblitererans syndrome (BOS) after lung transplantation. In: Winter Meeting of the British Thoracic Society. 2004, London: Thorax: BMJ Publishing Group.
• Bermano G, Pagmantidis V, Holloway N, Kadri S, Mowat A, Broom J, Hesketh JE. Glutathione peroxidase 4 gene polymorphism and susceptibility to colorectal cancer. In: Journal of Nutrition: International Research Conference on Food, Nutrition, and Cancer. 2004, Washington, DC, USA: American Society for Nutrition.
• McCartney L, Gilbert HJ, Bolam DN, Boraston A, Knox J. Glycoside hydrolase carbohydrate-binding modules as molecular probes for the analysis of plant cell wall polymers. Analytical Biochemistry 2004, 326(1), 49-54.
• Anderson CMH, Grenade DS, Boll M, Foltz M, Wake KA, Kennedy DJ, Munck LK, Miyauchi S, Taylor PM, Campbell FC, Munck BG, Daniel H, Ganapathy V, Thwaites DT. H⁺/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat. Gastroenterology 2004, 127(5), 1410-1422.
• Mills GW, Avery PJ, McCarthy MI, Hattersley AT, Levy JC, Hitman GA, Sampson M, Walker M. Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to Type 2 diabetes. Diabetologia 2004, 47(4), 732-738.
• Nichols CE, Dhaliwal B, Lockyer M, Hawkins AR, Stammers DK. High-resolution structures reveal details of domain closure and "half-of-sites-reactivity" in Escherichia coli aspartate β-semialdehyde dehydrogenase. Journal of Molecular Biology 2004, 341(3), 797-806.
• Baldwin MR, Lakey JH, Lax AJ. Identification and characterization of the Pasteurella multocida toxin translocation domain. Molecular Microbiology 2004, 54(1), 239-250.
• Schneider C, Will CL, Brosius J, Frilander MJ, Lührmann R. Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proceedings of the National Academy of Sciences 2004, 101(26), 9584-9589.
• Nile CJ, Townes CL, Michailidis G, Hirst BH, Hall J. Identification of chicken lysozyme g2 and its expression in the intestine. Cellular and Molecular Life Sciences 2004, 61(21), 2760-2766.
• Fong PY, Argent BE, Guggino WB, Gray MA. Identification of pancreatic K+ channels mediating ATP-stimulated Cl- secretion. In: FASEB Journal: Experimental Biology 2004 Meeting. 2004, Washington, DC, USA: Federation of American Societies for Experimental Biology.
• Pye D, Watt DJ, Walker C, Lightowlers RN, Turnbull DM. Identification of the RAG-1 as a suitable mouse model for mitochondrial DNA disease. Neuromuscular Disorders 2004, 14(5), 329-336.
• Leontiou C, Gilroy KL, Watters G, Austin CA. Identifying drug-resistant mutations in human topoisomerase II beta using a forced molecular evolution approach. In: Anticancer Research: 7th International Conference of Anticancer Research. 2004, Corfu, Greece: International Institute of Anticancer Research.
• Murphy DM, Forrest IA, Ward C, Pritchard G, Jones D, Egan JJ, Cawston TE, Corris PA, Lordan JL. IL-17 stimulates IL-8 release in primary epithelial cell cultures derived from lung allografts. In: Winter Meeting of the British Thoracic Society. 2004, London: Thorax: BMJ Publishing Group.
• Lie LH, Patole SN, Pike AR, Ryder LC, Connolly BA, Ward AD, Tuite EM, Houlton A, Horrocks BR. Immobilisation and synthesis of DNA on Si(111), nanocrystalline porous silicon and silicon nanoparticles. Faraday Discussions 2004, 125, 235-249.
• Visudtiphole V, Thomas MB, Chalton D, Lakey JH. In vitro refolding of trimeric and dimeric OmpF. In: Biophysical Society 48th Annual Meeting. 2004, Baltimore, MD: Biophysical Journal: Biophysical Society.
• Howard A, Goodlad RA, Walters JRF, Ford D, Hirst BH. Increased expression of specific intestinal amino acid and peptide transporter mRNA in rats fed by TPN is reversed by GLP-2. Journal of Nutrition 2004, 134(11), 2957-2964.
• Townes CL, Michailidis G, Nile CJ, Hall J. Induction of cationic chicken liver-expressed antimicrobial peptide 2 in response to Salmonella enterica infection. Infection and Immunity 2004, 72(12), 6987-6993.
• Ford D. Intestinal and placental zinc transport pathways. Proceedings of the Nutrition Society 2004, 63(1), 21-29.
• Dean P, Kenny B. Intestinal barrier dysfunction by enteropathogenic Escherichia coli is mediated by two effector molecules and a bacterial surface protein. Molecular Microbiology 2004, 54(3), 665–675.
• Fergie N, Bayston R, Pearson JP, Birchall JP. Is otitis media with effusion the result of a biofilm infection?. Clinical Otolaryngology 2004, 29(1), 38-46.
• Mickleburgh I, Burtle B, Nury D, Chabanon H, Chrzanowska-Lightowlers ZMA, Hesketh J. Isolation and identification of a protein binding to the localization element of Metallothionein-1 mRNA. Biochemical Society Transactions 2004, 32(5), 705-7066.
• Boese SH, Aziz O, Simmons NL, Gray MA. Kinetics and regulation of a Ca²⁺-activated Cl^- conductance in mouse renal inner medullary collecting duct cells. American Journal of Physiology - Renal Physiology 2004, 286(4), F682-F692.
• Mirkin MV, Lie LH, Houlton A, Horrocks BR. Lateral charge transfer in DNA monolayers. In: 205th Meeting of The Electrochemical Society. 2004, San Antonio, Texas, USA: Electrochemical Society, Inc.
• Flint JE, Nurizzo D, Harding S, Longman E, Davies G, Gilbert HJ, Bolam DN. Ligand-mediated dimerization of a carbohydrate-binding module reveals a novel mechanism for protein-carbohydrate recognition. Journal of Molecular Biology 2004, 337(2), 417-426.
• Yanagisawa S, Dennison C. Loop-contraction mutagenesis of type 1 copper sites. Journal of the American Chemical Society 2004, 126(48), 15711-15719.
• Biles BD, Connolly BA. Low-fidelity Pyrococcus furiosus DNA polymerase mutants useful in error-prone PCR. Nucleic Acids Research 2004, 32(22), e176.
• Kurz T, Leake A, von Zglinicki T, Brunk UT. Lysosomal redox-active iron is important for oxidative stress-induced DNA damage. In: Strategies for Engineered Negligible Senescence: Why Genuine Control of Aging May be Forseeable. 2004, Cambridge, UK: New York Academy of Sciences.
• Jepson MA, Clark MA, Hirst BH. M cell targeting by lectins: A strategy for mucosal vaccination and drug delivery. Advanced Drug Delivery Reviews 2004, 56(4), 511-525.
• Madgwick S, Nixon VL, Chang HY, Herbert M, Levasseur M, Jones KT. Maintenance of sister chromatid attachment in mouse eggs through maturation-promoting factor activity. Developmental Biology 2004, 275(1), 68-81.
• Errington J. Making money from microbes - case studies: spinning out. Microbiology Today 2004, 31(1), 10.
• Hegyi P, Rakonczay Jr Z, Gray MA, Argent BE. Measurement of Intracellular pH in Pancreatic Duct Cells: A New Method for Calibrating the Fluorescence Data. Pancreas 2004, 28(4), 427-434.
• Jia X, Weinert T, Lydall D. Mec1 and Rad53 Inhibit Formation of Single-Stranded DNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants. Genetics 2004, 166(2), 753-764.
• Susanna KA, van der Werff AF, den Hengst CD, Calles B, Salas M, Venema G, Hamoen LW, Kuipers OP. Mechanism of transcription activation at the comG promoter by the competence transcription factor ComK of Bacillus subtilis. Journal of Bacteriology 2004, 186(4), 1120-1128.
• Jayapaul MK, Walker M. Mechanisms contributing to the development of type 2 diabetes. British Journal of Diabetes and Vascular Disease 2004, 4(4), 227-231.
• Gagliardi D, Stepien PP, Temperley RJ, Lightowlers RN, Chrzanowska-Lightowlers ZMA. Messenger RNA stability in mitochondria: Different means to an end. Trends in Genetics 2004, 20(6), 260-267.
• Rutherford JC, Bird AJ. Metal-responsive transcription factors that regulate iron, zinc and copper homeostasis in eukaryotic cells. Eukaryotic Cell 2004, 3(1), 1-13.
• Koc A, Gasch AP, Rutherford JC, Kim HY, Gladyshev VN. Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. Proceedings of the National Academy of Sciences 2004, 101(21), 7999-8004.
• Blakely EL, He L, Taylor RW, Chinnery PF, Lightowlers RN, Schaefer AM, Turnbull DM. Mitochondrial DNA deletion in identical twins. Journal of Medical Genetics 2004, 41(2), e19.
• Lamb HK, Ren J, Park A, Johnson C, Leslie K, Cocklin S, Thompson P, Mee C, Cooper A, Stammers DK, Hawkins AR. Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis. Protein Science 2004, 13(12), 3127-3138.
• Pearson JP, Brownlee IA, Taylor C. Mucin genes in the GI tract. In: Williams, P.A., Phillips, G.O, ed. Gums and Stabilisers for the Food Industry. Cambridge: Royal Society of Chemistry, 2004, pp.517-525.
• N'Dow J, Pearson J, Neal D. Mucus production after transposition of intestinal segments into the urinary tract. World Journal of Urology 2004, 22(3), 178-185.
• Davidson DJ, Gray MA, Kilanowski FM, Tarran R, Randell SH, Sheppard DN, Argent BE, Dorin JR. Murine epithelial cells: Isolation and culture. Journal of Cystic Fibrosis 2004, 3(2), 59-62.
• Leontiou C, Lakey JH, Austin CA. Mutation E522K in human DNA topoisomerase IIβ confers resistance to methyl N-(4′-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4′-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide. Molecular Pharmacology 2004, 66(3), 430-439.
• Stevens R, McEntire R, Goble C, Greenwood M, Zhao J, Wipat A, Li P. myGrid and the drug discovery process. Drug Discovery Today: BIOSILICO 2004, 4(2), 140-148.
• Berrington A, Borriello SP, Brazier J, Duckworth G, Foster K, Freeman R, Gould FK, Henderson J, Hollyoak V, Spencer R, Taylor J, Wilcox M. National Clostridium difficile standards group: Report to the department of health. Journal of Hospital Infection 2004, 56(s1), 1-38.
• Wright AM, Gong X, Verdon B, Linsdell P, Mehta A, Riordan JR, Argent BE, Gray MA. Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. Journal of Biological Chemistry 2004, 279(40), 41658-41663.
• Kolesnikova OA, Entelis NS, Jacquin-Becker C, Goltzene F, Chrzanowska-Lightowlers ZM, Lightowlers RN, Martin RP, Tarassov I. Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells. Human Molecular Genetics 2004, 13(20), 2519-2534.
• Hong Q, Chalton DA, Visudtiphole V, Lakey JH. Omp F-ligand interactions measured in vivo by SPR. In: Biophysical Society 48th Annual Meeting. 2004, Baltimore, MD: Biophysical Journal: Biophysical Society.
• Hirt RP, Horner DS, ed. Organelles, Genomes and Eukaryote Phylogeny: An Evolutionary Synthesis in the Age of Genomics. Boca Raton, Florida, USA: CRC Press, 2004.
• Christensen SK, Maenhaut-Michel G, Mine N, Gottesman S, Gerdes K, Van Melderen L. Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system. Molecular Microbiology 2004, 51(6), 1705-1717.
• Chan LMS, Cooper AE, Dudley ALJ, Ford D, Hirst BH. P-glycoprotein potentiates CYP3A4-mediated drug disappearance during Caco-2 intestinal secretory detoxification. Journal of Drug Targeting 2004, 12(7), 405-413.
• Brownlee IA, Hart JL, Dore MPE, Fenton DI, Dettmar PW, Pearson JP. Pancreatic proteases retain activity through stomach-like conditions, and increase oesophageal damage by pepsin. In: 105th Annual Meeting of the American Gastroenterological Association. 2004, New Orleans, LA, USA: W.B. Saunders Co.
• Moore I, Sayer JA, Nayar A, Ahmed S, Tapson JS. Pantoprazole-induced acute interstitial nephritis. Journal of Nephrology 2004, 17(4), 580-581.
• Dennison C, Sato K. Paramagnetic 1H NMR Spectrum of the Cobalt(II) Derivative of Spinach Plastocyanin. Inorganic Chemistry 2004, 43(4), 1502-1510.
• Scheffers DJ, Errington J. PBP1 is a component of the Bacillus subtilis cell division machinery. Journal of Bacteriology 2004, 186(15), 5153-5156.
• Brownlee IA, Ward C, Forrest I, Pritchard G, Murphy D, Dark J, Corris PA, Pearson JP. Pepsin detection in the lungs of transplant patients: Evidence of gastric refluxate. In: 105th Annual Meeting of the American Gastroenterological Association. 2004, New Orleans, LA, USA: W.B. Saunders Co.
• Kristan K, Podlesek Z, Hojnik V, Gutierrez-Aguirre I, Guncar G, Turk D, Gonzalez-Manas JM, Lakey JH, Macek P, Anderluh G. Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable β-sandwich. Journal of Biological Chemistry 2004, 279(45), 46509-46517.
• Allenby NEE, O'Connor N, Pragai Z, Carter NM, Miethke M, Engelmann S, Hecker M, Wipat A, Ward AC, Harwood CR. Post-transcriptional regulation of the Bacillus subtilis pst operon encoding a phosphate-specific ABC transporter. Microbiology 2004, 150(8), 2619-2628.
• Sarvas M, Harwood CR, Bron S, Van Dijl JM. Post-translocational folding of secretory proteins in Gram-positive bacteria. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2004, 1694(1-3), 311-327.
• McFarland R, Taylor RW, Elson JL, Lightowlers RN, Turnbull DM, Howell N, Scaglia F, Vogel H, Hawkins EP, Vladutiu GD, Guan M-X, Liu L-L, Wong L-JC. Proving pathogenicity: When evolution is not enough. American Journal of Medical Genetics 2004, 131(1), 107-110.
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