Bacterial Biochemistry 
ICaMB's bacterial biochemists apply biophysical and biochemical methods to explore bacterial protein-interactions with complex-carbohydrates, other proteins, lipids, DNA, enzymes and metals. Properties of pure mutant proteins in vitro are often correlated with those of genetically manipulated cells carrying analogous mutations. A special interest lies in the biochemistry of pathogenic bacteria.
The blend of interests and techniques used include:
- Advanced protein characterisation (analytical ultracentrifugation, electron paramagnetic spectroscopy, isothermal and scanning calorimetry, stop-flow, UV-VIS and fluorescence spectroscopy, inductibly-coupled plasma mass spectroscopy, atomic absorption spectrophotometry);
- Macromolecular X-ray crystallography;
- Bio-inorganic chemistry;
- Pathogen host interactions;
- Mass spectrometry (Pinnacle).
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