Sensing and Signalling in Bacteria
Sensing is an important aspect of the ability of microorganisms to perceive their environment e.g. changing nutrient levels or the presence of toxins. Bacteria are extrodinarily well equipped to overcome adverse environments and are able to adapt their metabolism and induce developmental changes that ensure survival.
Research in this area is centered around:
- Protein-carbohydrate interactions in macromolecular and cellular recognition
- Gene regulation processes behind the heterogenic (bi-stable) cellular differentiation processes
- Microbial protein secretion
- Responses to environmental stress
- Gene expression and regulatory networks
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