Research Highlights
ICaMB fosters a number of competitive research teams and its research covers a wide spectrum of academic endeavour. Catch up with our most recent work:
- Dynamic control of the DNA replication initiation protein DnaA by Soj/ParA
- A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi
- Structural and biochemical evidence for a boat-like transition state in beta-mannosidases
- Why do eukaryotes have mitochondria?
You can also view other advancements achieved by ICaMB’s vibrant researchers:
- Ly49B is an important immunoregulator on myeloid cells
- Novel uracil protection mechanism stalls DNA replication preventing irreversible transmission of mutations
- Nucleoid occlusion resolved – newly discovered protein noc responsible for selection of the mid-cell site for cell division
- Chromosome segregation in bacteria utilises actin-based mechanism or actin evolved long before eukaryotes
- Macrolide antibiotics – definition of macrolide structure provides a platform for antibiotic remodelling
- Novel regulatory mechanism controls CFTR, a Cl- channel being central in cystic fibrosis and secretory diarrhoeas
- How mammalian eggs stop and start their meiotic cell cycle
- Effector proteins co-operate to trigger cellular changes in often deadly enteropathogenic E.coli infections
- Phosphorylation by polo kinase Cdc5p is crucial for transcriptional control during the cell cycle
- How metals find their way to the right metallo-proteins
- Ca-signalling in mitosis of higher organisms
- Decades-old dogma overturned – RNA polymerases form a novel kind of transcription elongation complex and do have “proof-reading” function
