Newcastle University

Research Interests

Ion channels, anion exchangers and cyst formation. Biophysical studies on the cellular mechanism of anion secretion by epithelial cells with particular reference to the inherited conditions cystic fibrosis and polycystic kidney disease.

• Kemeny LV, Hegyi P, Rakonczay Z, Borka K, Korompay A, Gray MA, Argent BE, Venglovecz V. Substance P Inhibits Pancreatic Ductal Bicarbonate Secretion via Neurokinin Receptors 2 and 3 in the Guinea Pig Exocrine Pancreas. Pancreas 2011, 40(5), 793-795.
• Pallagi P, Venglovecz V, Rakonczay Z, Borka K, Korompay A, Ozsvari B, Judak L, Sahin-Toth M, Geisz A, Schnur A, Maleth J, Takacs T, Gray MA, Argent BE, Mayerle J, Lerch MM, Wittmann T, Hegyi P. Trypsin Reduces Pancreatic Ductal Bicarbonate Secretion by Inhibiting CFTR Cl- Channels and Luminal Anion Exchangers. Gastroenterology 2011, 141(6), 2228-U413.
• Rakonczay Z, Ignath I, Venglovecz V, Szekely C, Hasegawa M, Inoue M, Takacs T, Lonovics J, Argent BE, Gray MA, Hegyi P. [Meeting Abstract] The Role of CFTR in the Stimulatory Effect of Chenodeoxycholate on Apical Anion Exchange Activity of Human Pancreatic Duct Cells. Pancreas 2009,38 8 1040.
• Ignath I, Hegyi P, Venglovecz V, Szekely CA, Carr G, Hasegawa M, Inoue M, Takacs T, Argent BE, Gray MA, Rakonczay Z. CFTR Expression But Not Cl- Transport Is Involved in the Stimulatory Effect of Bile Acids on Apical Cl-/HCO3- Exchange Activity in Human Pancreatic Duct Cells. Pancreas 2009, 38(8), 921-929.
• Venglovecz V, Rakonczay Z, Hegyi P, Argent BE, Gray MA. Chenodeoxycholate Activates Ion Channels in Guinea Pig Pancreatic Duct Cells. In: Pancreas: 40th Anniversary Meeting of American Pancreatic Association and Japan Pancreas Society.2009,Honolulu, Hawaii:Lippincott Williams & Wilkins
• Rakonczay Jr Z, Hegyi P, Hasegawa M, Inoue M, You J, Iida A, Ignáth I, Alton EWFW, Griesenbach U, Óvári G, Vág J, Da Paula AC, Crawford RM, Varga G, Amaral MD, Mehta A, Lonovics J, Argent BE, Gray MA. CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector.. Journal of Cellular Physiology 2008, 214(2), 442-455.
• Hegyi P, Rakonczay Z Jr, Farkas K, Venglovecz V, Ozsvari B, Seidler U, Gray MA, Argent BE. Controversies in the role of SLC26 anion exchangers in pancreatic ductal bicarbonate secretion. Pancreas 2008. , 37(2), 232-234.
• Venglovecz V, Rakonczay Jr Z, Ozsvari B, Takacs T, Lonovics J, Varro A, Gray MA, Argent BE, Hegyi P. Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig. Gut 2008, 57(8), 1102-1112.
• Ferrari S, Griesenbach U, Iida A, Farley R, Wright AM, Zhu J, Munkonge FM, Smith SN, You J, Ban H, Inoue M, Chan M, Singh C, Verdon B, Argent BE, Wainwright B, Jeffery PK, Geddes DM, Porteous DJ, Hyde SC, Gray MA, Hasegawa M, Alton EWFW. Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Therapy 2007, 14(19), 1371-1379.
• Argent BE, Gray MA, Steward MC, Case RM. Cell physiology of pancreatic ducts. In:Johnson, LR, ed. Physiology of the Gastrointestinal Tract.San Diego:Elsevier,2006, pp. 1371-1396.
• Rakonczay Jr Z, Fearn A, Hegyi P, Boros I, Gray MA, Argent BE. Characterization of H+ and HCO3- transporters in CFPAC-1 human pancreatic duct cells. World Journal of Gastroenterology 2006, 12(6), 885-895.
• Rakonczay Z, Fearn A, Hegyi P, Gray MA, Argent BE. Characterization of H⁺ and HCO₃^- transporters in CFPAC-1 human pancreatic duct cells. In: 37th European Pancreatic Club Meeting. 2005, Graz, Austria.
• Heygi P, Ordog B, Rakonczai Jr Z, Takacs T, Lonovics J, Szabolcs A, Sari R, Toth A, Papp JG, Varro A, Kovacs MK, Gray MA, Argent BE, Boldogkoi Z. Effect of herpesvirus infection on pancreatic duct cell secretion. World Journal of Gastroenterology 2005, 11(38), 5997-6002.
• Hegyi P, Rakonczay Jr Z, Tiszlavicz L, Varro A, Toth A, Racz G, Varga G, Gray MA, Argent BE. Protein kinase C mediates the inhibitory effect of substance P on HCO 3- secretion from guinea pig pancreatic ducts. American Journal of Physiology: Cell Physiology 2005,288 5 C1030-C1041.
• Rakonczay Z, Fearn A, Feber EA, Hegyi P, Gray MA, Argent BE. A novel basolateral bicarbonate transport mechanism in human pancreatic duct cells. In: 36th European Pancreatic Club Meeting. 2004, Padova, Italy.
• Fong PY, Argent BE, Guggino WB, Gray MA. Identification of pancreatic K+ channels mediating ATP-stimulated Cl- secretion. In: FASEB Journal: Experimental Biology 2004 Meeting.2004,Washington, DC, USA:Federation of American Societies for Experimental Biology
• Hegyi P, Rakonczay Jr Z, Gray MA, Argent BE. Measurement of Intracellular pH in Pancreatic Duct Cells: A New Method for Calibrating the Fluorescence Data. Pancreas 2004,28 4 427-434.
• Davidson DJ, Gray MA, Kilanowski FM, Tarran R, Randell SH, Sheppard DN, Argent BE, Dorin JR. Murine epithelial cells: Isolation and culture. Journal of Cystic Fibrosis 2004,3 2 59-62.
• Wright AM, Gong X, Verdon B, Linsdell P, Mehta A, Riordan JR, Argent BE, Gray MA. Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. Journal of Biological Chemistry 2004,279 40 41658-41663.
• Fong P, Argent BE, Guggino WB, Gray MA. Characterization of vectorial chloride transport pathways in the human pancreatic duct adenocarcinoma cell line HPAF. American Journal of Physiology - Cell Physiology 2003,285 2 C433-C445.
• Fong PY, Argent BE, Guggino WB, Gray MA. Molecular & functional analysis of Cl- and K+ channels in HPAF cells. Faseb Journal 2003,17 4 A469-A469.
• Ferrari S, Farley R, Munkonge F, Griesenbach U, Smith SN, You J, Tokusumi T, Iida A, Wainwright B, Gray M, Wright A, Verdon B, Argent B, Geddes DM, Hasegawa M, Alton EWFW. Recombinant Sendai virus-mediated CFTR cDNA transfer. In: Molecular Therapy: 6th Annual Meeting of the American Society of Gene Therapy. 2003, Washington, DC, USA: Nature Publishing Group.
• Wright AM, Argent BE, Gray MA. Regulation of CFTR by extracellular anions is modulated by cytosolic calcium and phosphatase activity. Journal of General Physiology 2003,122 1 56.
• Hegyi P, Gray MA, Argent BE. Substance P inhibits bicarbonate secretion from guinea pig pancreatic ducts by modulating an anion exchanger. American Journal of Physiology - Cell Physiology 2003,285 2 C268-C276.
• Hegyi P, Gray MA, Argent BE. Substance P inhibits bicarbonate secretion in guinea pig panceatic ducts by modulating an anion exchanger. Gastroenterology 2003, 124(4), A439-A439.
• Gray MA, Winpenny JP, Verdon B, O'Reilly CM, Argent BE. Properties and role of calcium-activated chloride channels in pancreatic duct cells. In: Fuller, C.M, ed. Calcium-Activated Chloride Channels. Maryland Heights, Missouri, USA: Academic Press, 2002, pp.231-256.
• Tarran R, Loewen ME, Paradiso AM, Olsen JC, Gray MA, Argent BE, Boucher RC, Gabriel SE. Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances. Journal of General Physiology 2002, 120(3), 407-418.
• Sohma Y, Gray MA, Imai Y, Argent BE. 150 mM HCO₃^- - How does the pancreas do it? Clues from computer modelling of the duct cell. Journal of the Pancreas 2001, 2(suppl. 4), 198-202.
• Gray MA, O'Reilly C, Winpenny J, Argent B. Functional interactions of HCO3- with cystic fibrosis transmembrane conductance regulator. Journal of the Pancreas 2001, 2(4 (suppl.)), 207-211.
• Gray M, O'Reilly C, Winpenny J, Argent B. Anion interactions with CFTR and consequences for HCO3- transport in secretory epithelia. Journal of Korean Medical Science 2000, 15, S12-S15.
• O'Reilly CM, Winpenny JP, Argent BE, Gray MA. Cystic fibrosis transmembrane conductance regulator currents in guinea pig pancreatic duct cells: inhibition by bicarbonate ions. Gastroenterology 2000, 118(6), 1187-1196.
• O'Reilly CM, Winpenny JP, Argent BE, Gray MA. Cystic fibrosis transmembrane conductance regulator currents in guinea pig pancreatic duct cells: Inhibition by bicarbonate ions. Gastroenterology 2000, 118(6), 1187-1196.
• Tarran R, Argent BE, Gray MA. Regulation of a hyperpolarization-activated chloride current in murine respiratory ciliated cells. Journal of Physiology 2000, 524(2), 353-364.
• Argent BE, O'Reilly CM, Winpenny JP, Gray MA. Regulation of CFTR by bicarbonate ions. In: BRITISH JOURNAL OF PHARMACOLOGY. 2000.
• Adair J, Jackson K, Gray MA, Argent BE. The effects of protein kinase C on calcium mobilisation in a human pancreatic duct cell line (HPAF). In: JOURNAL OF PHYSIOLOGY-LONDON. 2000.
• J. Adair,B.E. Argent,M. A. Gray. ATP-induced [Ca2+]i oscillations in a human pancreatic duct cell line (HPAF).. J. Physiol. (Lond) 1999, 517P, 96P.
• M A Gray,C M O'Reilly,J P Winpenny,B E Argent. Bicarbonate inhibits CFTR: implications for pancreatic ductal bicarbonate secretion. Journal of Physiology 1999, (Proceedings), (in press).
• Y Sohma,M A Gray,Y Imai,B E Argent. Computer simulation of HCO3- secretion by the pancreatic ductal tree. Journal of Physiology 1999, (Proceedings)((in press)).
• Becq F, Mettey Y, Gray MA, Galietta LJV, Dormer RL, Merten M, Metaye T, Chappe V, Marvingt-Mounir C, Zegarra-Moran O, Tarran R, Bulteau L, Derand R, Pereira MMC, McPherson MA, Rogier C, Joffre M, Argent BE, Sarrouilhe D, Kammouni W, Figarella C, Verrier B, Gola M, Vierfond J-M. Development of substituted benzo[c]quinolizinium compounds as novel activators of the cystic fibrosis chloride channel. Journal of Biological Chemistry 1999, 274(39), 27415-27425.
• Y. Sohma,A. Harris,B. E. Argent,M. A. Gray. A novel type of internal barium block of a maxi-K+ channel from human vas deferens epithelial cells. Biophysical Journal 1998, 74(1), 199-209.
• R. Tarran,M. A. Gray,M. J. Evans,W. H. Colledge,R. Ratcliff,B. E. Argent. Basal chloride currents in murine airway epithelial cells: modulation by CFTR. Am J Physiol Cell Physiol 1998, 274(4), C904-913.
• J P Winpenny,A Harris,M A Hollingsworth,B E Argent,M A Gray. Calcium-activated chloride conductance in pancreatic adenocarcinoma cell line of ductal origin (HPAF) and in freshly isolated human pancreatic duct cells. Pflügers Archiv 1998, 435, 796-803.
• B E Argent,M A Gray. Regulation and formation of fluid and electrolyte secretions by pancreatic ductal epithelium. In: A E Sirica;D S Longnecker, ed. Biliary and pancreatic ductal epithelia. Pathobiology and pathophysiology. New York: Marcel Dekker, 1997, pp. 349-377.
• B E Argent,J P Winpenny,Y Sohma,Y Imai,M A Gray. The role of the duct cell in CF pancreatic disease. Pediatric Pulmonology 1997, Supplement 14, 112-113.
• M A Gray,J P Winpenny,B E Argent. Extracellular HCO3- inhibits CFTR chloride conductance in pancreatic duct cells. Pediatric Pulmonology 1996, Supplement 13, 235.
• R L Evans,N Ashton,A C Elliott,R Green,B E Argent. Interactions between secretin and acetylcholine in the regulation of fluid secretion by isolated rat pancreatic ducts. Journal of Physiology 1996, 496.1, 265-273.
• R Tarran,M A Gray,M J Evans,R Colledge,R Ratcliffe,B E Argent. Putative 'alternate' Cl- conductances in wild-type and CF mouse nasal epithelial cells. Pediatric Pulmonology 1996, Supplement 13, 237.
• R Tarran,Gray MA,BE Argent. A hyperpolarization-activated chloride current in ciliated cells isolated from murine nasal epithelium. Journal of Physiology 1995, 489P, 97.
• J. P. Winpenny,B. Verdon,H. L. McAlroy,W. H. Colledge,R. Ratcliff,M. J. Evans,M. A. Gray,B. E. Argent. Calcium-Activated Chloride Conductance Is Not Increased In Pancreatic Duct Cells Of Cf Mice. Pflugers Arch. 1995, 430(1), 26-33.
• A. N. Smith,C. J. C. Wardle,J. P. Winpenny,B. Verdon,M. A. Gray,B. E. Argent,A. Harris. Camp-Activated Chloride Channels in a Cftr-Transfected Pancreatic Adenocarcinoma-Derived Cell-Line, Pans6. Biochimica Et Biophysica Acta-Molecular Basis of Disease 1995, 1271(2-3), 315-320.
• R Tarran,M A Gray,M J Evans,W H Colledge,R Ratcliff,B E Argent. Cl- conductances in nasal epithelia of CF mice. Pediatric Pulmonology 1995, Supplement 12, 198.
• Y Sohma,M A Gray,Y Imai,B E Argent. Effects of apical Cl- conductance on HCO3- secretion by a computer model of rat pancreatic duct cells.. Journal of Physiology 1995, 482, 31P.
• J. P. Winpenny,H. L. McAlroy,M. A. Gray,B. E. Argent. Protein kinase C regulates the magnitude and stability of CFTR currents in pancreatic duct cells. Am J Physiol Cell Physiol 1995, 268(4), C823-828.
• B Verdon,J P Winpenny,K J Whitfield,B E Argent,M A Gray. Volume-activated chloride currents in pancreatic duct cells. Journal of Membrane Biology 1995, 147, 173-183.
• M. A. Gray,J. P. Winpenny,D. J. Porteous,J. R. Dorin,B. E. Argent. CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. Am J Physiol Cell Physiol 1994, 266(1), C213-221.
• B E Argent,R M Case. Pancreatic ducts. Cellular mechanism and control of bicarbonate secretion.. In: L R Johnson, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press, 1994, pp. 1473-1497.
• M A Gray,S Plant,B E Argent. cAMP-regulated whole cell chloride currents in pancreatic duct cells. American Journal of Physiology 1993, 264, C591-C602.
• Y Sohma,B E Argent,M A Gray,Y Imai. Computer model of pancreatic duct cells. Journal of Physiology 1993, 467, 243P.
• R. M. Case,B. E. Argent. Pancreatic duct secretion: control and mechanisms of transport. In: V. L. W. Go;E. P. DiMagno;J. D. Gardner;E. Lebenthal;H. A. Reber;G. A. Scheele, ed. The Pancreas: Biology, Pathobiology, and Disease. New York: Raven Press, 1993, pp. 301-350.
• N Ashton,R L Evans,A C Elliott,R Green,B E Argent. Regulation of fluid secretion and intracellular messengers in isolated rat pancreatic ducts by acetylcholine. Journal of Physiology 1993, 471, 549-562.
• A Harris,B E Argent. The cystic fibrosis gene and its product CFTR. Seminars in Cell Biology 1993, 4, 37-44.
• S Plant,M A Gray,B E A Argent. K+ channels on pancreatic duct cells. Journal of Physiology 1992, 452, 360P.
• M A Gray,B E Argent. Properties of a cyclic AMP-regulated chloride conductance in isolated rat pancreatic duct cells. Journal of Physiology 1992, 446, 353P.
• N Ashton,R L Evans,B E Argent. Protein kinase C has an inhibitory role in the control of fluid secretion in isolated pancreatic ducts. Journal of Physiology 1992, 452, 99P.
• B E Argent,S Githens,S Kalser,D S Longnecker,R Metzgar,J A Williams. The pancreatic duct cell. Pancreas 1992, 7, 403-419.
• J M Lingard,L Al-Nakkesh,N Taylor,B E Argent. 125I efflux from a human pancreatic adenocarcinoma cell line (BxPC-3).. Journal of Physiology 1991, 446, 354P.
• R L Evans,N Ashton,A C Elliott,R Green,B E Argent. A calcium pathway for activation of fluid secretion by pancreatic ducts.. Pediatric Pulmonology,Suppl 1991, 6, 253.
• J M Lingard,L Al-Nakkesh,N Taylor,A Harris,B E Argent. Acetylcholine and ionomycin stimulate 125I efflux from a human pancreatic cell line (BxPC-3).. Pediatric Pulmonology,Suppl 1991, 6, 263.
• N Ashton,B E Argent,R Green. Characteristics of fluid secretion from isolated rat pancreatic ducts stimulated with secretin and bombesin. Journal of Physiology 1991, 435, 533-546.
• C E Pollard,A Harris,L Coleman,B E Argent. Chloride channels on epithelial cells cultured from human fetal epididymis. Journal of Membrane Biology 1991, 124, 275-284.
• J M Lingard,L Al-Nakkash,B E Argent. Effects of gut hormones and adenosine compounds on (125)I efflux from human pancreatic adenocarcinoma cells (BxPC-3). Proceedings of the Australian Physiological and Pharmacological Society 1991, 22, 159P.
• M A Gray,B E Argent. The cyclic AMP-regulated chloride conductance of pancreatic ducts cells.. Pediatric Pulmonology,Suppl. 1991, 6, 251.
• M A Gray,C E Pollard,A Harris,L Coleman,J R Greenwell,B E Argent. Anion selectivity and block of the small conductance chloride channel on pancreatic duct cells. American Journal of Physiology 1990, 259 (Cell Physiol. 28), C752-C761.
• M A Gray,C E Pollard,A Harris,L Coleman,B E Argent. Anion selectivity and block of the small conductance chloride channel on pancreatic duct cells. Pediatric Pulmonology, Suppl 1990, 5, 210.
• M. A. Gray,C. E. Pollard,A. Harris,L. Coleman,J. R. Greenwell,B. E. Argent. Anion selectivity and block of the small-conductance chloride channel on pancreatic duct cells. American Journal of Physiology 1990, 259, C752-C761.
• C E Pollard,N Hampton,A Harris,L Coleman,B E Argent. Chloride channels on human epididymal cells. In: P Y D Wong;J A Young, ed. Exocrine Secretion II. 1990, pp. 111-112.
• C E Pollard,A Harris,L Coleman,B E Argent. Chloride channels on human epididymal cells {in vitro}. Journal of Physiology 1990, 426, 72P.
• N Ashton,B E Argent,R Green. Effect of vasoactive intestinal peptide, bombesin and substance P on fluid secretion by isolated rat pancreatic ducts. Journal of Physiology 1990, 427, 471-482.
• M A Gray,C E Pollard,A Harris,L Coleman,N Ashton,R Green,A J Garton,B E Argent. Hormone-regulated ion channels on pancreatic duct cells: their role in bicarbonate secretion. In: P Y D Wong;J A Young, ed. Exocrine Secretion II. Hong Kong: Hong Kong University Press, 1990, pp. 57-60.
• M A Gray,B E Argent. Non-selective cation channel on pancreatic duct cells. Biochimica et Biophysica Acta 1990, 1029, 33-42.
• B E Argent,M A Gray. Pancreatic ducts: isolation, culture and bicarbonate transport. In: C J Jones, ed. Epithelia: Advances in Cell Physiology and Cell Culture. Lancaster: Kluwer Academic Publishers, 1990, pp. 69-97.
• R M Case,B E Argent. Pancreatic secretion: in vivo, perfused gland, and isolated duct studies. In: S Fleischer;B Fleischer, ed. Methods in Enzymology: Biomembranes Biological Transport. Vol 192. Part II. Chpt. 56. Orlando: Academic Press, 1990, pp. 256-271.
• M A Gray,C E Pollard,A Harris,L Coleman,B E Argent. Recent advances in understanding pancreatic duct cell function: implications for CF.. Pediatric Pulmonology,Suppl 1990, 5, 181-182.
• M A Gray,J R Greenwell,A J Garton,B E Argent. Regulation of maxi-K+ channels on pancreatic duct cells by cyclic AMP-dependent phosphorylation. Journal of Membrane Biology 1990, 115, 203-215.
• M A Gray,J R Greenwell,B E Argent. The role of ion channels in the mechanism of pancreatic bicarbonate secretion. In: J A Young;P Y D Wong, ed. Epithelial Secretion of Electrolytes and Water. Berlin: Springer-Verlag, 1990, pp. 251-265.
• C E Pollard,A Harris,L Coleman,B E Argent. Two types of chloride channel on duct cells cultured from human fetal epididymus.. Pediatric Pulmonology,Suppl 1990, 5, 212.
• M A Gray,C E Pollard,B E Argent,J R Greenwell,L Coleman,A Harris. A rectifying chloride channel on duct cells cultured from human pancreas.. Pediatric Pulmonology,Suppl 1989, 4, 46P.
• B E Argent,M A Gray. Bicarbonate secretion by pancreatic duct cells. In: R M Case, ed. The Exocrine Pancreas. Proceedings of the 10th BSG/SK&F International Workshop 1989. Welwyn Garden City (UK): Smith Kline & French Laboratories Ltd., 1989, pp. 24-28.
• C E Pollard,M A Gray,L Coleman,J R Greenwell,A Harris,B E Argent. Characterisation of a small conductance chloride channel on duct cells cultured from human pancreas.. Pediatric Pulmonology,Suppl 1989, 4, 118.
• J I Gillespie,C Hedley,J R Greenwell,B E Argent. Chloride-bicarbonate exchange in isolated rat pancreatic acini. Quarterly Journal of Experimental Physiology 1989, 74, 883-895.
• R M Case,B E Argent. Pancreatic secretion of electrolytes and water.. In: S G Schultz;J G Forte;B B Rauner, ed. Handbook of Physiology: The Gastrointestinal System Vol III (Section 6). New York: Oxford University Press, 1989, pp. 383-417.
• M A Gray,J R Greenwell,B E Argent. Regulation of a maxi-K+ channel in pancreatic duct cells by cyclic AMP-dependent phosphorylation.. In: D Keeling;C Benham, ed. Ion Transport. London: Academic Press, 1989, pp. 356.
• M A Gray,A Harris,L Coleman,J R Greenwell,B E Argent. Two types of chloride channel on duct cells cultured from human fetal pancreas. American Journal of Physiology 1989, 257 (Cell Physiol. 26), C240-C251.
• M A Gray,B E Argent,L Coleman,A Harris. Anion-selective channel on the apical plasma membrane of epithelial cells derived from normal and CF human pancreas.. In:proc,16th International Cystic Fibrosis Conference . Sydney\ Australia, 1988, pp. 41-42.
• B E Argent,L Coleman,M A Gray,J R Greenwell,A Harris. Anion-selective channel on the apical plasma membrane of human pancreatic duct cells in vitro.. Journal of Physiology 1988, 403, 49P.
• M A Gray,L Coleman,A Harris,J R Greenwell,B E Argent. Chloride channels on human pancreatic duct cells. In: P Y D Wong;J A Young, ed. Exocrine Secretion. Hong Kong: Hong Kong University Press, 1988, pp. 73-75.
• M A Gray,J R Greenwell,B E Argent. Ion channels in pancreatic duct cells and their role in bicarbonate secretion. In: P Y D Wong;J A Young, ed. Exocrine Secretion. Hong Kong: Hong Kong University Press, 1988, pp. 77,80.
• M A Gray,J R Greenwell,B E Argent. Ion channels in pancreatic duct cells: characterization and role in bicarbonate secretion.. In: G Mastella;P M Quinton, ed. Cellular and Molecular Basis of Cystic Fibrosis. San Francisco: San Francisco Press, 1988, pp. 205-216.
• B E Argent,A Fahey,J I Gillespie,J R Greenwell. Measurement of intracellular chloride fluctuations in isolated rat pancreatic acinar cells using the chloride-sensitive dye 6-methoxy-N-[3-sulfopropyl] quinolinium (SPQ).. Journal of Physiology 1988, 410, 46P.
• M A Gray,J R Greenwell,B E Argent. Secretin-regulated chloride channel on the apical plasma membrane of pancreatic duct cells. Journal of Membrane Biology 1988, 105, 131-142.
• B E Argent,S Arkle,R Green. Secretory studies on isolated rat pancreatic ducts. In: J S Davison;E Shaffer, ed. Gastrointestinal and hepatic secretions: mechanisms and control. Calgary: University of Calgary Press, 1988, pp. 250-251.
• M A Gray,B E Argent,J R Greenwell,L Coleman,A Harris. Anion-selective channel on the apical plasma membrane of epithelial cells derived from human pancreas. Pediatric Pulmonology,Suppl. 1987, 1, 12.
• B E Argent,M A Gray,J R Greenwell. Characteristics of a large conductance anion channel in membrane patches excised from rat pancreatic duct cells in vitro.. Journal of Physiology 1987, 394, 46P.
• B E Argent,J I Gillespie,J R Greenwell. Optical measurement of intracellular pH (pHi) in single isolated rat pancreatic acini: evidence of Cl-/HCO3- exchange.. Journal of Physiology 1987, 394, 93P.
• B E Argent,M A Gray,J R Greenwell. Secretin-regulated anion channel on the apical membrane of rat pancreatic duct cells in vitro. Journal of Physiology 1987, 391, 33P.
• B E Argent,S Arkle,M Gray,J R Greenwell. Two types of calcium-sensitive cation channels in isolated rat pancreatic duct cells.. Journal of Physiology 1987, 386, 82P.
• R M Case,B E Argent. Bicarbonate secretion by pancreatic duct cells: mechanisms and control. In: V L W Go;J D Gardner;F P Brooks;E Lebenthal;E P Di Magno;G A Scheele, ed. The Exocrine Pancreas: Biology, Pathology and Diseases. New York: Raven Press, 1986, pp. 213-243.
• S Arkle,C M Lee,M J Cullen,B E Argent. Isolation of ducts from the pancreas of copper-deficient rats.. Quarterly Journal of Experimental Physiology 1986, 71, 249-265.
• S Arkle,P D Pickford,P S Schofield,C Ward,B E Argent. Mechanism of the inhibitory effect of trifluoperazine on isoprenaline-evoked amylase secretion from isolated rat parotid glands. Biochemical Pharmacology 1986, 35, 4121-4124.
• B E Argent,S Arkle,M J Cullen,R Green. Morphological, biochemical and secretory studies on rat pancreatic ducts maintained in tissue culture. Quarterly Journal of Experimental Physiology 1986, 71, 633-648.
• R M Case,T-A Ansah,S Dho,A J Howorth,B E Argent. Second messenger interactions in pancreas and salivary glands.. Biomedical Research 1986, 7 (Supplement 2), 95-103.
• B E Argent,S Arkle,R Green. Secretory properties of isolated rat pancreatic ducts.. In: Proceedings of the International Union of Physiological Sciences,XVI,. 1986.
• B E Argent,S Arkle. Mechanism of action of extracellular calcium on isoprenaline-evoked amylase secretion from isolated rat parotid glands.. Journal of Physiology 1985, 369, 337-353.
• B E Argent,S Arkle,R Green. Micropuncture studies on isolated panceatic ducts.. Digestion 1985, 32, 163.
• S Arkle,B E Argent. Morphological and biochemical studies on rat pancreatic ducts maintained in tissue culture.. Gut 1985, 26, A1132.
• B E Argent,S Arkle. Biochemical studies on pancreatic ducts isolated from copper-deficient rats.. Journal of Physiology 1984, 354, 90P.
• S Arkle,B E Argent. Isolation of ducts from the rat pancreas.. In: D Lawson, ed. Cystic Fibrosis: Horizons. New York: Wiley and Sons, 1984, pp. 354.
• S Arkle,B E Argent. Studies on ducts isolated from the rat pancreas.. Digestion 1984, 30, 74.
• B E Argent,S Arkle. The effects of trifluoperazine on amylase secretion by the in vitro rat parotid gland.. Journal of Physiology 1984, 354, 39P.
• B E Argent,S Arkle. Isolation of ducts from the rat pancreas.. Journal of Physiology 1983, 342, 81P.
• B E Argent,S Arkle. The effects of extracellular Ca2+-deprivation on amylase secretion by the rat parotid gland.. Journal of Physiology 1983, 342, 47P.
• B E Argent,F C Hirst,E Poong. The effects of frusemide on (86)Rb fluxes into rat liver slices incubated in vitro.. British Journal of Pharmacology 1982, 7, 559P.
• S Arkle,B E Argent. Ca(2+) and cAMP interactions during B-adrenergic stimulation of amylase secretion from the rat parotid gland.. In:Advances in Physiological Sciences vol 28 Saliva and Salivation . Akademai Kiado: Pergamon, 1981, pp. 201-205.
• B E Argent,P A Smith. Subcellular fractionation of pancreatic ductal tissue.. In: A Ribet;L Pradayrol;C Susini, ed. Biology of Normal and Cancerous Exocrine Pancreatic Cells. INSERM Symposium No.15. North Holland Biomedical Press. Elsevier, 1980, pp. 6164.
• F C Hirst,C J Scott-Wilson,R M Case,B E Argent. The effects of extracellular Ca(2+) deprivation and Mn(2+) on pancreatic amylase secretion.. In: A Ribet;L Pradayrol;C Susini, ed. Biology of Normal and Cancerous Exocrine Pancreatic Cells. INSERM Symposium No. 15. Elsevier: North Holland Biomedical Press, 1980, pp. 61-64.
• B E Argent,R M Case,J R Greenwell,F C Hirst. The effect of extracellular calcium concentration on amylase secretion and (45)Ca efflux from rat pancreas stimulated by caerulein and by acetylcholine.. Journal of Physiology 1978, 282, 27P-28P.
• B E Argent,R M Case,F C Hirst. The effect of phorbol myristate acetate on amylase secretion and (45)Ca efflux from rat pancreas.. Journal of Physiology 1978, 285, 33P.
• B E Argent,R M Case,F C Hirst,C J Scott-Wilson. Calcium-binding to rat pancreas microsomal membranes.. Journal of Physiology 1977, 273, 60P-70P.
• B E Argent,R M Case,F C Hirst. Effects on manganese on amylase secretion and calcium efflux in rat pancreas.. Journal of Physiology 1977, 269, 70P-71P.
• B E Argent,R K Smith,R M Case. The role of calcium in pancreatic enzyme and electrolyte secretion.. In: R M Case;H Geobell, ed. Stimulus-Secretion Coupling in the Gastrointestinal Tract.. Lancaster: MTP, 1976, pp. 237-254.
• B E Argent,R M Case,R K Smith. Hyperosmolarity, calcium movements and enzyme secretions in rat pancreas.. Journal of Physiology 1975, 252, 76P-78P.
• B E Argent,R K Smith,R M Case. The distribution of bivalent cation-stimulated ATP hydrolysis and calcium accumulation in subcellular fractions of rat pancreas.. Biochemical Society Transactions 1975, 3, 713-714.
• B E Argent,R M Case,T Scratcherd. Amylase secretion by the perfused cat pancreas in relation to the secretion of calcium and other electrolytes and as influenced by the external ionic environment. Journal of Physiology 1973, 230, 575-593.
• B E Argent,R M Case,M P Fraser,T Scratcherd. The effects of calcium on volume and amylase secretion from the perfused cat pancreas.. Journal of Physiology 1972, 224, 29P-30P.
• B E Argent,R M Case,L M Poole,T Scratcherd. Stimulation of amylase secretion from the perfused cat pancreas by potassium.. Journal of Physiology 1970, 208, 79P-80P.