Dr Christopher Dennison
Senior Lecturer
- Email: christopher.dennison@ncl.ac.uk
- Telephone: +44 (0) 191 222 7127
- Fax: 0191 222 6929
- Address: Cookson Building
University of Newcastle upon Tyne
Newcastle upon Tyne
NE2 4HH
Research Interests
The main area of research is Bioinorganic Chemistry with particular emphasis on metalloproteins. The current focus is copper-containing proteins and we use a multi-disciplinary approach to study the relationship between their structure and function. Areas of expertise incorporate biological NMR, including the study of paramagnetic proteins with this technique, and also biological electron-transfer reactions.
Selected Publications
- S. Yanagisawa, P. B. Crowley, S. J. Firbank, A. T. Lawler, D. M. Hunter, W. McFarlane, C. Li, T. Kohzuma, M. J. Banfield and C. Dennison. pi-interaction tuning of the active site properties of metalloproteins. The Journal of the American Chemical Society 2008, in press.
- C. Li, M. J. Banfield and C. Dennison. Engineering Copper Sites in Proteins: Loops Confer Native Structures and Properties to Chimeric Cupredoxins. Journal of the American Chemical Society 2007, 129, 709-718.
- C. Li;S. Yanagisawa;B. M. Martins;A. Messerschmidt;M. J. Banfield;C. Dennison. Basic requirements for a metal-binding site in a protein: The influence of loop shortening on the cupredoxin azurin. Proceedings of the National Academy of Sciences of the United States of America 2006, 103(19), 7258-7263.
- K. Sato, P. B. Crowley and C. Dennison. Transient Protein Interactions between Ctytochrome f and the Phytocyanin Umecyanin. ChemBioChem 2007, 8, 732-735.
- K. Sato and C. Dennison. Active Site Comparison of Co(II) Blue and Green Nitrite Reductases. Chemistry a European Journal 2006, 12, 6647-6659.
- K. J. Waldron, S. Tottey, S. Yanagisawa, C. Dennison and N. J. Robinson. A Periplasmic Iron-binding Protein Contributes toward Inward Copper Supply. The Journal of Biological Chemistry 2007, 282(6), 3837-3846.
