Newcastle University

Publications

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• Blackwood JK, Williamson SC, Greaves LC, Wilson L, Rigas AC, Sandher R, Pickard RS, Robson CN, Turnbull DM, Taylor RW, Heer R. In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells. Journal of Pathology 2011, 225(2), 181-188.
• Morris CM, Ballard CG, Allan L, Rowan E, Stephens S, Firbank MJ, Ford GA, Kenny RA, O'Brien JT, Kalaria RN. NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. Neurobiology of Aging 2011, 32(3), 554.e1-554.e6.
• Burn J, Bishop DT, Chapman PD, Elliott F, Bertario L, Dunlop MG, Eccles D, Ellis A, Evans DG, Fodde R, Maher ER, Moslein G, Vasen HFA, Coaker J, Phillips RKS, Bulow S, Mathers JC, for the International CAPP Consortium. A Randomized Placebo-Controlled Prevention Trial of Aspirin and/or Resistant Starch in Young People with Familial Adenomatous Polyposis. Cancer Prevention Research 2011, 4(5), 655-665.
• Vasudev A, O'Brien JT, Tan MP, Parry SW, Thomas AJ. A study of orthostatic hypotension, heart rate variability and baroreflex sensitivity in late-life depression. Journal of Affective Disorders 2011, 131(1-3), 374-378.
• Plagnol V, Nalls MA, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simon-Sanchez J, Schulte C, Lesage S, Sveinbjornsdottir S, Amouyel P, Arepalli S, Band G, Barker RA, Bellinguez C, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen HL, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Durr A, Edkins S, Evans JR, Foltynie T, Freeman C, Gao JJ, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gustafsson O, Harris C, Hellenthal G, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang XM, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jonsson PV, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris H, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Pearson R, Perlmutter JS, Petursson H, Pirinen M, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, de Silva R, Smith C, Spencer CCA, Stefansson H, Steinberg S, Stockton JD, Strange A, Su Z, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Vandrovcova J, Velseboer D, Vidailhet M, Vukcevic D, Walker R, van de Warrenburg B, Weale ME, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefansson K, Martinez M, Donnelly P, Singleton AB, Hardy J, Heutink P, Brice A, Gasser T, Wood NW, WTCCC2. A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease. PLoS Genetics 2011, 7(6), e1002142.
• Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Kerkhof HJM, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Loughlin J, McCaskie A, Ollier WER, Ralston SH, Spector TD, Wallis GA, Wilkinson JM, Aslam N, Birell F, Carluke I, Joseph J, Rai A, Reed M, Walker K, arcOGEN Consortium, Doherty SA, Jonsdottir I, Maciewicz RA, Muir KR, Metspalu A, Rivadeneira F, Stefansson K, Styrkarsdottir U, Uitterlinden AG, van Meurs JBJ, Zhang W, Valdes AM, Doherty M, Zeggini E. A variant in MCF2L is associated with osteoarthritis. American Journal of Human Genetics 2011, 89(3), 446-450.
• Nesbitt V, Pitceathly RDS, Rahman S, Hanna MG, McFarland R, Turnbull DM. A3243G - more than just MELAS!. In: UK Neuromuscular Translational Research Conference. 2011, London: Neuromuscular Disorders: Pergamon.
• Maj M, Ilhan A, Neziri D, Gartner W, Berggard T, Attems J, Base W, Wagner L. Age related changes in pancreatic beta cells: A putative extra-cerebral site of Alzheimer's pathology. World Journal of Diabetes 2011, 2(4), 49-53.
• Stoll EA, Cheung W, Mikheev AM, Sweet I, Bielas J, Zhang J, Rostomily RC, Horner PJ. Aging neural progenitor cells have decreased mitochondrial content and lower oxidative metabolism. Journal of Biological Chemistry 2011, 286(44), 33592-33601.
• Kirkwood TBL. All our tomorrows: the science of human ageing. In: FEBS Journal: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine. 2011, Torino, Italy: Wiley-Blackwell Publishing Ltd.
• Patanwala I, Walter R, Mells GF, Kometa S, Newton JL, Alexander GJ, Hudson M, Jones DE. An externally-validated clinical tool for the prediction of gastro-oesophageal varices in patients with PBC - the Newcastle varices in PBC (NVP) score. In: Hepatology: 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). 2011, San Francisco, California, USA: John Wiley & Sons, Inc.
• Neganova I, Vilella F, Atkinson SP, Lloret M, Passos JF, von Zglinicki T, O'Connor JE, Burks D, Jones R, Armstrong L, Lako M. An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells. Stem Cells 2011, 29(4), 651-659.
• Keane PC, Judge SJ, Blain PG, Morris CM. An investigation into the mechanism of trichloroethylene neurotoxicity in relation to Parkinsonism. In: Annual Congress of The British Toxicology Society. 2011, Durham: Elsevier Ireland Ltd.
• Irving L, Alston C, Craven L, Herbert M, Turnbull DM. Analysis of mitochondrial DNA mutant loads in oocytes & preimplantation embryos for the 14709T > C & 14487T > C mtDNA mutations by pyrosequencing. In: Neuromuscular Disorders: United Kingdom Neuromuscular Translational Research Conference. 2011, London, UK: Elsevier Ltd.
• Morris CM. Any old iron?. Brain 2011, 134(4), 924-927.
• Martin Ruiz C, Jagger C, Kingston A, Collerton J, Catt M, Davies K, Dunn M, Hilkens C, Keavney B, Pearce S, den Elzen W, Talbot D, Wiley L, Bond J, Mathers J, Eccles M, Robinson L, James O, Kirkwood T, von Zglinicki T. Assessment of a large panel of candidate biomarkers of ageing in the Newcastle 85+ study. Mechanisms of Ageing and Development 2011, 132(10), 496-502.
• Pearce M, Groom A, Relton C, Pollard T, Parker L, Francis R. Associations between sex hormones and bone mineral density and bone resorption in 50 year old men: The Newcastle thousand families study. In: Journal of Epidemiology & Community Health: IEA World Congress of Epidemiology. 2011, Edinburgh, UK: BMJ Group.
• Stansby G, Macdonal S, Allison R, de Belder M, Brown MM, Dark J, Featherstone R, Flather M, Ford GA, Halliday A, Malik I, Naylor R, Pepper J, Rothwell PM. Asymptomatic carotid disease and cardiac surgery consensus. Angiology 2011, Online ahead of print.
• Savy CY, Morris CM, Blain PG, Judge SJ. Behavioural effects of low level exposure to organophosphate pesticides. Toxicology 2011, 290(2-3), 116.
• Pearce MS, Groom A, Relton CL, Peaston RT, Pollard TM, Francis RM. Birth weight and early socio-economic disadvantage as predictors of sex hormones and sex hormone binding globulin in men at age 49–51 years. American Journal of Human Biology 2011, 23(2), 185-189.
• McKay JA, Xie L, Harris S, Wong YK, Ford D, Mathers JC. Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice. Molecular Nutrition & Food Research 2011, 55(7), 1026-1035.
• Shaw LC, Price CIM, van Wijck FMJ, Shackley P, Steen N, Barnes MP, Ford GA, Graham LA, Rodgers H, on behalf of the BoTULS Investigators. Botulinum Toxin for the Upper Limb After Stroke (BoTULS) Trial: Effect on Impairment, Activity Limitation, and Pain. Stroke 2011, 42(5), 1371-1379.
• Aspray TJ, Francis RM. Calcium and vitamin D supplementation and cardiovascular disease: quo vadis?. Maturitas 2011, 69(4), 285-286.
• Jagger C, Collerton JC, Davies K, Kingston A, Robinson LA, Eccles MP, von Zglinicki T, Martin-Ruiz C, James OFW, Kirkwood TBL, Bond J. Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs. BMC Geriatrics 2011, 11, 21.
• Attems J, Papassotiropoulos A, Saido TC, Griffin WS, Mrak RE, Kolsch H, Tredici KD, Ghebremedhin E, Thal DR. Capillary CAA defines a subtype of Alzheimer's disease while pericapillary A beta is a type of early A beta deposition. In: Proceedings of the 112th Meeting of the British Neuropathological Society. 2011, Wiley-Blackwell Publishing Ltd.
• Khundakar AA, Morris CM, Oakley AE, Thomas AJ. Cellular pathology within the anterior cingulate cortex of patients with late-life depression: A morphometric study. Psychiatry Research: Neuroimaging 2011, 194(2), 184-189.
• Firbank MJ, He J, Blamire AM, Singh B, Danson P, Kalaria RN, O'Brien JT. Cerebral blood flow by arterial spin labeling in poststroke dementia. Neurology 2011, 76(17), 1478-1484.
• Collerton D, Collerton J, Jagger J, Bond J, Saxby BK, Brooker H, McKeith IG, Kirkwood T. Cognitive Performance in a UK Cohort of 85 Year Olds: The Newcastle 85+ Study. In: Journal of Psychophysiology: International Conference “Aging & Cognition”. 2011, Dortmund, Germany: Hogrefe Publishing Corp.
• Parkinson KN, Pearce M, Dale A, Reilly JJ, Drewett RF, Wright CM, Relton CL, McArdle P, Le Couteur AS, Adamson AJ. Cohort Profile: The Gateshead Millennium Study. International Journal of Epidemiology 2011, 40(2), 308-317.
• Avery PJ, Patel SK, Ibrahim IM, Walker M, Keavney BD. Common variation in the adiponectin gene has an effect on systolic blood pressure. Journal of Human Hypertension 2011, 25(12), 719-724.
• Aribisala BS, He JB, Blamire AM. Comparative Study of Standard Space and Real Space Analysis of Quantitative MR Brain Data. Journal of Magnetic Resonance Imaging 2011, 33(6), 1503-1509.
• Jones D, Patanwala I, Newton J. Comparison of the PBC-40 and PBC-27 tools for quality of life assessment in English speaking primary biliary cirrhosis patients. In: Gut: Annual Meeting of the British Society of Gastroenterology. 2011, Birmingham, UK: BMJ Group.
• Watzka SB, Kostler WJ, Attems J. Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established [reply]. European Journal of Cardio-Thoracic Surgery 2011, 39(3), 428-428.
• Watzka SB, Kostler WJ, Attems J. Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established: Author Reply. European Journal of Cardio-Thoracic Surgery 2011, 39(3), 428.
• Mckay JA, Adriaens M, Xie L, Manus C, Evelo CT, Ford D, Mathers JC. Consequences of Folate Depletion during Development and High Fat Intake from Weaning on Adiposity, Gene Expression and DNA Methylation in Adult Mice. In: Journal of Developmental Origins of Health and Disease: 7th World Congress on Developmental Origins of Health and Disease. 2011, Portland, Oregon, USA: Cambridge University Press.
• McKay JA, Ford D, Relton CL, Evelo CT, Adriaens M, Mathers JC. Consequences of Folate Depletion during Development for DNA Methylation and Gene Expression in the Fetal Mouse. In: Journal of Developmental Origins of Health and Disease: 7th World Congress on Developmental Origins of Health and Disease. 2011, Portland, Oregon, USA: Cambridge University Press.
• Pekovic V, Gibbs-Seymour I, Markiewicz E, Alzoghaibi F, Benham AM, Edwards R, Wenhert M, von Zglinicki T, Hutchison CJ. Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation. Aging Cell 2011, 10(6), 1067-1079.
• Hurt CS, Thomas BA, Burn DJ, Hindle JV, Landau S, Samuel M, Wilson KCM, Brown RG. Coping in Parkinson's disease: an examination of the coping inventory for stressful situations. International Journal of Geriatric Psychiatry 2011, 26(10), 1030-1037.
• Colloby SJ, Firbank MJ, Vasudev A, Parry SW, Thomas AJ, O'Brien JT. Cortical thickness and VBM-DARTEL in late-life depression. Journal of Affective Disorders 2011, 133(1-2), 158-164.
• Kirkwood TBL. Current key developments. Clinical Medicine 2011, 11(2), 169-170.
• Dodd AW, Rodriguez-Fontenla C, Calaza M, Carr A, Gomez-Reino JJ, Tsezou A, Reynard LN, Gonzalez A, Loughlin J. Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus. Osteoarthritis and Cartilage 2011, 19(4), 430-434.
• Taylor J-P, O'Brien J. Dementia with Lewy bodies – Clinical Aspects: E-brain module. Joint Neurosciences Council, 2011. Available at: http://www.ebrainjnc.com.
• Skytthe A, Valensin S, Jeune B, Cevenini E, Balard F, Beekman M, Bezrukov V, Blanche H, Bolund L, Broczek K, Carru C, Christensen K, Christiansen L, Collerton JC, Cotichini R, de Craen AJM, Dato S, Davies K, De Benedictis G, Deiana L, Flachsbart F, Gampe J, Gilbault C, Gonos ES, Haimes E, Hervonen A, Hurme MA, Janiszewska D, Jylha M, Kirkwood TBL, Kristensen P, Laiho P, Leon A, Marchisio A, Masciulli R, Nebel A, Passarino G, Pelicci G, Peltonen L, Perola M, Poulain M, Rea IM, Remade J, Robine JM, Schreiber S, Scurti M, Sevini F, Sikora E, Skouteri A, Slagboom PE, Spazzafumo L, Stazi MA, Toccaceli V, Toussaint O, Tornwall O, Vaupel JW, Voutetakis K, Franceschi C, GEHA Consortium. Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project. Experimental Gerontology 2011, 46(11), 934-945.
• Fave G, Beckmann M, Lloyd AJ, Zhou SB, Harold G, Lin WC, Tailliart K, Xie L, Draper J, Mathers JC. Development and validation of a standardized protocol to monitor human dietary exposure by metabolite fingerprinting of urine samples. Metabolomics 2011, 7(4), 469-484.
• Wood JS, Firbank MJ, Mosimann UP, Taylor JP, O'Brien JT. Development of a Novel fMRI Compatible Visual Perception Prototype Battery to Test Older People With and Without Dementia. Journal of Geriatric Psychiatry and Neurology 2011, 24(2), 73-83.
• Yarnall AJ, Hayes L, Hawthorne GC, Candlish C, Aspray TJ. Diabetes in care homes: Residents' experience of care. In: Age and Ageing: Communications to the British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
• Nesbitt V, Bates MGD, Turnbull DM, McFarland R. Diabetes is a risk factor for hypertension in adults with the m.3243A > G mitochondrial DNA mutation. In: UK Neuromuscular Translational Research Conference. 2011, London: Neuromuscular Disorders: Pergamon.
• Manthorpe J, Keady J, Bond J, Robinson L, Samsi K. Dialogues around diagnostic disclosure for people with dementia and carers. In: GSA Annual Scientific Meeting Abstracts. 2011, Boston, Massachusetts, USA: Oxford University Press.
• Mckay JA, Mathers JC. Diet induced epigenetic changes and their implications for health. Acta Physiologica 2011, 202(2), 103-118.
• Greaves LC, Barron MJ, Campbell-Shiel G, Kirkwood TBL, Turnbull DM. Differences in the accumulation of mitochondrial defects with age in mice and humans. Mechanisms of Ageing and Development 2011, 132(11-12), 588-591.
• Thornton JK, Taylor KM, Ford D, Valentine RA. Differential Subcellular Localization of the Splice Variants of the Zinc Transporter ZnT5 Is Dictated by the Different C-Terminal Regions. PLoS One 2011, 6(8), e23878.
• Firbank MJ, Blamire AM, Teodorczuk A, Teper E, Mitra D, O'Brien JT. Diffusion tensor imaging in Alzheimer's disease and dementia with Lewy bodies. Psychiatry Research: Neuroimaging 2011, 194(2), 176-183.
• Relton CL, Groom A, St Pourcain B, Sayers AE, Swan DC, Embleton ND, Pearce MS, Ring SM, Northstone K, Tobias JH, Ness AR, Shaheen SO, Smith GD. DNA Methylation Patterns in Cord Blood DNA Predict Body Size in Childhood. In: Journal of Developmental Origins of Health and Disease: 7th World Congress on Developmental Origins of Health and Disease. 2011, Portland, Oregon, USA: Cambridge University Press.
• Fratter C, Raman P, Alston CL, Blakely EL, Craig K, Smith C, Evans J, Seller A, Czermin B, Pitceathly RDS, Hanna MG, Poulton J, Brierley C, Staunton TG, Tumpenny PD, Schaefer AM, Chinnery PF, Horvath R, Tumbull DM, Gorman GS. Dominant and recessive RRM2B mutations are frequent in familial PEO with multiple mtDNA deletions. In: Journal of Medical Genetics: British Human Genetics Conference. 2011, Warwick, Coventry: BMJ Group.
• Fratter C, Raman P, Alston C, Blakely EL, Craig K, Smith C, Evans J, Seller A, Czermin B, Hanna MG, Poulton J, Brierley C, Staunton TG, Turnpenny PD, Schaefer AM, Chinnery PF, Horvath R, Turnbull DM, Gorman GS, Taylor RW. Dominant and recessive RRM2B mutations cause familial PEO and multiple mtDNA deletions in muscle. In: Neuromuscular Disorders: United Kingdom Neuromuscular Translational Research Conference. 2011, London, UK: Elsevier Ltd.
• Burn DJ. Editor's Introduction to Hot Topics in Movement Disorders: Literature Highlights. Movement Disorders 2011, 26(1), 4-4.
• McKay JA, Williams EA, Mathers JC. Effect of maternal and post weaning folate supply on gene-specific DNA methylation in the small intestine of weaning and adult Apc+/Min and wild type mice. Frontiers in Epigenomics 2011, 2, 23.
• Lim EL, Hollingsworth KG, Smith FE, Thelwall PE, Taylor R. Effects of raising muscle glycogen synthesis rate on skeletal muscle ATP turnover rate in type 2 diabetes. American Journal of Physiology - Endocrinology and Metabolism 2011, 301(6), E1155-E1162.
• Narayan SK, Firbank MJ, Saxby BK, Stansby G, Hansrani M, O'Brien JT, Ford GA. Elevated plasma homocysteine is associated with increased brain atrophy rates in older subjects with mild hypertension. Dementia and Geriatric Cognitive Disorders 2011, 31(5), 341-348.
• Flynn D, Stobbart L, Murtagh MJ, Price C, Rodgers H, Ford GA, Thomson RG. Engaging Clinicians, Patients and Family Members in the Development of Decision Support for Hyperacute Stroke. In: International Stroke Conference. 2011, Los Angeles, CA: Stroke: American Heart Association.
• Groom A, Elliott HR, Embleton ND, Relton CL. Epigenetics and child health: basic principles. Archives of Disease in Childhood 2011, 96, 863-869.
• Bergmann MM, Mathers JC. Ethical challenges in human nutrigenomics research. Maturitas 2011, 68(4), 297-298.
• Kowald A, Kirkwood TBL. Evolution of the mitochondrial fusion-fission cycle and its role in aging. Proceedings of the National Academy of Sciences 2011, 108(25), 10237-10242.
• Murphy JL, Shang E, Taivassalo T, Haller RG, Taylor RW, Turnbull DM. Exercise training in patients with mitochondrial myopathy: the analysis of COX-intermediate fibres. In: Neuromuscular Disorders: United Kingdom Neuromuscular Translational Research Conference. 2011, London, UK: Elsevier Ltd.
• Dickinson RE, Griffin H, Bigley V, Reynard LN, Hussain R, Haniffa M, Lakey JH, Rahman T, Wang XN, McGovern N, Pagan S, Cookson S, McDonald D, Chua I, Wallis J, Cant A, Wright M, Keavney B, Chinnery PF, Loughlin J, Hambleton S, Santibanez-Koref M, Collin M. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood 2011, 118(10), 2656-2658.
• Elstner M, Morris CM, Heim K, Bender A, Mehta D, Jaros E, Klopstock T, Meitinger T, Turnbull DM, Prokisch H. Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death. Acta Neuropathologica 2011, 122(1), 75-86.
• Reynard LN, Bui C, Canty-Laird EG, Young DA, Loughlin J. Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation. Human Molecular Genetics 2011, 20(17), 3450-3460.
• Chalmers KH, Kenwright AM, Parker D, Blamire AM. F-19-Lanthanide Complexes With Increased Sensitivity for F-19-MRI: Optimization of the MR Acquisition. Magnetic Resonance in Medicine 2011, 66(4), 931-936.
• Collerton J, Kingston A, Davies K, Bond J, Eccles M, Jagger C, Kirkwood T, Newton J. Falls are common in 85 year olds, are associated with physical and psychological morbidity, and have marked consequences for health services: Results from the Newcastle 85+ Study. In: Age and Ageing: British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
• Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R. Fasting Successfully Treats Early Diabetes Type 2. Forschende Komplementaermedizin 2011, 18(6), 359-360.
• Newton JL, Reese JA, Watson SI, Vesely SK, Bolton-Maggs PHB, George JN, Terrell DR. Fatigue in adult patients with primary immune thrombocytopenia. European Journal of Haematology 2011, 86(5), 420-429.
• Jones DEJ, Gray J, Frith J, Newton JL. Fatigue severity remains stable over time and independently associated with orthostatic symptoms in chronic fatigue syndrome: a longitudinal study. Journal of Internal Medicine 2011, 269(2), 182-188.
• McKay JA, Adriaens M, Xie L, Evelo CT, Relton CL, Ford D, Mathers JC. Folate Depletion during Development Causes Gene Expression Changes in Fetal and Adult Mouse Liver. In: Journal of Developmental Origins of Health and Disease: 7th World Congress on Developmental Origins of Health and Disease. 2011, Portland, Oregon, USA: Cambridge University Press.
• Newton JL, Elliott C, Frith J, Ghazala C, Pairman J, Jones DEJ. Functional capacity is significantly impaired in primary biliary cirrhosis and is related to orthostatic symptoms. European Journal of Gastroenterology and Hepatology 2011, 23(7), 566-572.
• Lord S, Baker K, Nieuwboer A, Burn D, Rochester L. Gait variability in Parkinson's disease: an indicator of non-dopaminergic contributors to gait dysfunction?. Journal of Neurology 2011, 258(4), 566-572.
• Jones EL, Kalaria RN, Sharp SI, O'Brien JT, Francis PT, Ballard CG. Genetic Associations of Autopsy-Confirmed Vascular Dementia Subtypes. Dementia and Geriatric Cognitive Disorders 2011, 31(4), 247-253.
• Loughlin J. Genetic indicators and susceptibility to osteoarthritis. British Journal of Sports Medicine 2011, 45(4), 278-282.
• Timofeeva MN, McKay JD, Smith GD, Johansson M, Byrnes GB, Chabrier A, Relton C, Ueland PM, Vollset SE, Midttun O, Nygard O, Slimani N, Romieu I, Clavel-Chapelon F, Boutron-Ruault MC, Fagherazzi G, Kaaks R, Teucher B, Boeing H, Weikert C, Bueno-de-Mesquita HB, van Gils C, Peeters PHM, Agudo A, Barricarte A, Huerta JM, Rodriguez L, Sanchez MJ, Larranaga N, Khaw KT, Wareham N, Allen NE, Travis RC, Gallo V, Norat T, Krogh V, Masala G, Panico S, Sacerdote C, Tumino R, Trichopoulou A, Lagiou P, Trichopoulos D, Rasmuson T, Hallmans G, Riboli E, Vineis P, Brennan P. Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC. Cancer Epidemiology, Biomarkers & Prevention 2011, 20(10), 2250-2261.
• Kilpelainen TO, Zillikens MC, Stancakova A, Finucane FM, Ried JS, Langenberg C, Zhang WH, Beckmann JS, Luan JA, Vandenput L, Styrkarsdottir U, Zhou YH, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Doring A, Eiriksdottir G, Estrada K, Fernandez-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimaki M, Klopp N, Kuhnel B, Kuusisto J, Liu YM, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellstrom D, Mitchell BD, Mooser V, Moreno JM, Mannisto S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvanen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJF. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics 2011, 43(8), 753-U58.
• Loughlin J. Genetics of osteoarthritis. Current Opinion in Rheumatology 2011, 23(5), 479-483.
• Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, Kanoni S, Peden JF, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker DJP, Barnes D, Dennison EM, Eriksson JG, Eriksson P, Eury E, Folkersen L, Fox CS, Frayling TM, Goel A, Gu HF, Horikoshi M, Isomaa B, Jackson AU, Jameson KA, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos RJF, Luan JA, Makrilakis K, Manning AK, Martinez-Larrad MT, Narisu N, Mannila MN, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer AA, Sennblad B, Silveira A, Stancakova A, Stirrups K, Swift AJ, Syvanen AC, Tuomi T, van 't Hooft FM, Walker M, Weedon MN, Xie WJ, Zethelius B, Ongen H, Malarstig A, Hopewell JC, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson CG, Lind L, Cooper CC, Serrano-Rios M, Ferrannini E, Forsen TJ, Clarke R, Franzosi MG, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins FS, Laakso M, Dermitzakis ET, Boehnke M, McCarthy MI, Wareham NJ, Groop L, Pattou F, Gloyn AL, Dedoussis GV, Lyssenko V, Meigs JB, Barroso I, Watanabe RM, Ingelsson E, Langenberg C, Hamsten A, Florez JC, DIAGRAM Consortium, GIANT Consortium, MuTHER Consortium, CARDIoGRAM Consortium, C4D Consortium. Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes. Diabetes 2011, 60(10), 2624-2634.
• Hribal ML, Presta I, Procopio T, Marini MA, Stancakova A, Kuusisto J, Andreozzi F, Hammarstedt A, Jansson PA, Grarup N, Hansen T, Walker M, Stefan N, Fritsche A, Haring HU, Pedersen O, Smith U, Laakso M, Sesti G, on behalf of the EUGENE2 Consortium. Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B. Diabetologia 2011, 54(4), 795-802.
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