Newcastle University

Publications

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• Thelwall PE, Simpson NE, Rabbani ZN, Clark MD, Pourdeyhimi R, Macdonald JM, Blackband SJ, Gamcsik MP. In vivo MR studies of glycine and glutathione metabolism in a rat mammary tumor. NMR in Biomedicine 2012, 25(2), 271-278.
• Pratt AG, Swan DC, Richardson S, Wilson G, Hilkens C, Young DA, Isaacs JD. A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly anti-citrullinated peptide antibodies-negative disease. Annals of the Rheumatic Diseases 2012, 71, 1374-1381.
• Goodship JA, Hall D, Topf A, Mamasoula C, Griffin H, Rahman TJ, Glen E, Tan H, Doza JP, Relton CL, Bentham J, Bhattacharya S, Cosgrove C, Brook D, Granados-Riveron J, Bu'Lock FA, O'Sullivan J, Stuart AG, Parsons J, Cordell HJ, Keavney B. A Common Variant in the PTPN11 Gene Contributes to the Risk of Tetralogy of Fallot. Circulation: Cardiovascular Genetics 2012, 5(3), 287-292.
• Dalle Pezze P, Sonntag AG, Thien A, Prentzell MT, Godel M, Fischer S, Neumann-Haefelin E, Huber TB, Baumeister R, Shanley DP, Thedieck K. A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation. Science Signaling 2012, 5(217), ra25.
• Hobbs N, Godfrey A, Mathers J, Rochester L, McDonald S, Araujo-Soares V, White M, Sniehotta F. A meta-analysis of physical activity interventions in the 'retirement window'. In: “Resiliance and Health” : 26th Conference of the European Health Psychology Society. 2012, Prague, Czech Republic: Routledge.
• Sonntag AG, Pezze PD, Shanley DP, Thedieck K. A modelling-experimental approach reveals insulin receptor substrate (IRS)-dependent regulation of adenosine monosphosphate-dependent kinase (AMPK) by insulin. FEBS Journal 2012, 279(18), 3314-3328.
• Sonntag AG, Dalle Pezze P, Shanley DP, Thedieck K. A modelling-experimental approach reveals IRS dependent regulation of AMPK by Insulin. FEBS Journal 2012, 279(18), 3314-3328.
• Horvath R, Holinski Feder E, Neeve VC, Pyle A, Griffin H, Ashok D, Foley C, Hudson G, Rautenstrauss B, Nürnberg G, Nürnberg P, Kortler J, Neitzel B, Bäßmann I, Rahman T, Keavney B, Loughlin J, Hambleton S, Schoser B, Lochmüller H, Santibanez Koref M, Chinnery PF. A new phenotype of brain iron accumulation with dystonia, optic atrophy, and peripheral neuropathy. Movement Disorders 2012, 76(6), 789-793.
• Craig K, Young MJ, Blakely EL, Longley MJ, Turnbull DM, Copeland WC, Taylor RW. A p.R369G POLG2 mutation associated with adPEO and multiple mtDNA deletions causes decreased affinity between polymerase gamma subunits. Mitochondrion 2012, 12(2), 313-319.
• Nelson G, Wordsworth J, Wang CF, Jurk D, Lawless C, Martin-Ruiz C, von Zglinicki T. A senescent cell bystander effect: senescence-induced senescence. Aging Cell 2012, 11(2), 345-349.
• Lawless C, Jurk D, Gillespie CS, Shanley D, Saretzki G, von Zglinicki T, Passos JF. A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations. PLoS One 2012, 7(2), e32117.
• Avery L, Flynn D, van Wersch A, Sniehotta FF, Trenell MI. A systematic review of behaviour change interventions targeting physical activity, exercise and HbA1c in adults with Type 2 diabetes. In: Diabetes UK Annual Professional Conference. 2012, Glasgow, UK: Wiley-Blackwell.
• McAuley MT, Wilkinson DJ, Jones JJL, Kirkwood TBL. A whole body mathematical model of cholesterol metabolism and its age associated dysregulation. BMC Systems Biology 2012, 6(1), 130.
• Horvath R, Czermin B, Gulati S, Demuth S, Houge G, Pyle A, Dineiger C, Blakely EL, Hassani A, Foley C, Brodhun M, Storm K, Kirschner J, Gorman GS, Lochmuller H, Holinski-Feder E, Taylor RW, Chinnery PF. Adult-onset cerebellar ataxia due to mutations in CABC1/ADCK3. Journal of Neurology, Neurosurgery and Psychiatry 2012, 83(2), 174-178.
• Pitceathly RDS, Smith C, Fratter C, Alston CL, He LP, Craig K, Blakely EL, Evans JC, Taylor J, Shabbir Z, Deschauer M, Pohl U, Roberts ME, Jackson MC, Halfpenny CA, Turnpenny PD, Lunt PW, Hanna MG, Schaefer AM, McFarland R, Horvath R, Chinnery PF, Turnbull DM, Poulton J, Taylor RW, Gorman GS. Adults with RRM2B-related mitochondrial disease have distinct clinical and molecular characteristics. Brain 2012, 135(11), 3392-3403.
• Wang H, Young DA, Cawston TE. Age-related knee joint cartilage changes in mice. In: Autumn Meeting of the British Society for Matrix Biology (BSMB). 2012, Newcastle upon Tyne, UK: Wiley-Blackwell Publishing Ltd.
• Proctor CJ, Pienaar IS, Elson JL, Kirkwood TBL. Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer's disease: A stochastic modelling approach. Molecular Neurodegeneration 2012, 7(1), 32.
• Ratnayake M, Reynard LN, Raine EVA, Santibanez-Koref M, Loughlin J. Allelic expression analysis of the osteoarthritis susceptibility locus that maps to MICAL3. BMC Medical Genetics 2012, 13(1), 12.
• Hatton AL, Dixon J, Rome K, Newton JL, Martin DJ. Altering gait by way of stimulation of the plantar surface of the foot: the immediate effect of wearing textured insoles in older fallers. Journal of Foot and Ankle Research 2012, 5(s1), 11.
• Stephan BC, Matthews FE, Ma B, Muniz G, Hunter S, Davis D, McKeith IG, Foster G, Ince PG, Brayne C. Alzheimer and Vascular Neuropathological Changes Associated with Different Cognitive States in a Non-Demented Sample. Journal of Alzheimer's Disease 2012, 29(2), 309-318.
• Yarnall AJ, Burn DJ. Amantadine-induced myoclonus in a patient with progressive supranuclear palsy. Age and Ageing 2012, 41(5), 695-696.
• Godfrey A, Lord S, Dadirayi M, Burn D, Rochester L. Ambulatory activity but not sedentary behaviour discriminates early Parkinson's disease and controls. In: Joint World Congress of ISPGR and Gait & Mental Function. 2012, Trondheim, Norway.
• Blain A, Greally E, Laval S, Blamire A, MacGowan G, Straub V. Animal Models of Duchenne Muscular Dystrophy, with Special Reference to the mdx Mouse. Biocybernetics and Biomedical Engineering 2012, 32(4), 3-15.
• Kofler BM, Miles EA, Curtis P, Armah CK, Tricon S, Grew J, Napper FL, Farrell L, Lietz G, Packard CJ, Caslake MJ, Mathers JC, Williams CM, Calder PC, Minihane AM. Apolipoprotein E genotype and the cardiovascular disease risk phenotype: Impact of sex and adiposity (the FINGEN study). Atherosclerosis 2012, 221(2), 467-470.
• Munafo MR, Timofeeva MN, Morris RW, Prieto-Merino D, Sattar N, Brennan P, Johnstone EC, Relton C, Johnson PCD, Walther D, Whincup PH, Casas JP, Uhl GR, Vineis P, Padmanabhan S, Jefferis BJ, Amuzu A, Riboli E, Upton MN, Aveyard P, Ebrahim S, Hingorani AD, Watt G, Palmer TM, Timpson NJ, Smith GD, EPIC Study Grp. Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure. Journal of the National Cancer Institute 2012, 104(10), 740-748.
• Kwok CS, Clark A, Ford GA, Durairaj R, Dixit AK, Davis J, Sharma AK, Potter JF, Myint PK. Association between prestroke disability and inpatient mortality and length of acute hospital stay after acute stroke. Journal of the American Geriatrics Society 2012, 60(4), 726-732.
• Rodriguez-Fontenla C, Carr A, Gomez-Reino JJ, Tsezou A, Loughlin J, Gonzalez A. Association of a BMP5 microsatellite with knee osteoarthritis: case-control study. Arthritis Research & Therapy 2012, 14(6), R257.
• Kalaria RN, Perry RH, O'Brien J, Jaros E. Atheromatous disease in small intracerebral vessels, microinfarcts and dementia. Neuropathology and Applied Neurobiology 2012, 38(5), 505-508.
• Firbank MJ, Teodorczuk A, O'Brien JT. Authors' Reply: Assessing the role of cerebrovascular disease in the incidence of geriatric depression Reply. British Journal of Psychiatry 2012, 201(5), 412-412.
• Newton JL, Frith J, Powell D, Hackett K, Wilton K, Bowman S, Price E, Pease C, Andrews J, Emery P, Hunter J, Gupta M, Vadivelu S, Giles I, Isenberg D, Lanyon P, Jones A, Regan M, Cooper A, Moots R, Sutcliffe N, Bombardieri M, Pitzalis C, McLaren J, Young-Min S, Dasgupta B, Griffiths B, Lendrem D, Mitchell S, Ng WF, UK Primary Sjogrens Syndrome. Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjogren's syndrome. Annals of the Rheumatic Diseases 2012, 71(12), 1973-1979.
• Houseman M, Potter C, Marshall N, Lakey R, Cawston T, Griffiths I, Young-Min S, Isaacs JD. Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up. Arthritis Research & Therapy 2012, 14(1), R30.
• Blain A, Greally E, MacGowan G, Laval S, Blamire A, Gillender K, Lochmuller H, Bushby K, Straub V. Beta-blocker/ACE-inhibitor combination treatment in mdx mice. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Turcot V, Groom A, McConnell JC, Pearce MS, Potter C, Embleton ND, Swan DC, Relton CL. Bioinformatic selection of putative epigenetically regulated loci associated with obesity using gene expression data. Gene 2012, 499(1), 99-107.
• Sinha N, Firbank M, O'Brien JT. Biomarkers in dementia with Lewy bodies: a review. International Journal of Geriatric Psychiatry 2012, 27(5), 443-453.
• Barron E, Lara J, White M, Mathers J. Blood-borne biomarkers of mortality: A systematic literature review of prospective cohort studies. In: 8th World Congress on Aging and Physical Activity: A Celebration of Diversity and Inclusion in Active Ageing. 2012, Glasgow, UK: Human Kinetics.
• McDonald C, Pearce M, Newton J, Kerr S. Bood pressure variability is associated with cognitive impairment in community dwelling older persons and is a predictor of cognitive decline. In: 8th World Congress on Aging and Physical Activity: A Celebration of Diversity and Inclusion in Active Ageing. 2012, Glasgow, UK: Human Kinetics.
• Hanson PS, Blain PG, Mulligan J, Morris CM. Brominated flame retardants - Neurotoxic to humans?. In: Health Protection. 2012, University of Warwick.
• Staley H, Bradburn DM, Mathers JC. Buccal cells as a potential surrogate for DNA methylation biomarker to identify those at increased colorectal cancer risk. In: Digestive Disorders Federation Meeting. 2012, Liverpool, UK: BMJ Group.
• Staley H, Bradburn DM, Mathers JC. Buccal cells as a potential surrogate for DNA methylation biomarker to identify those at increased colorectal cancer risk. In: International Surgical Congress of the Association of Surgeons of Great Britain and Ireland (ASGBI). 2012, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
• Jones SP, Dickinson HA, Ford GA, Gibson JME, Leathley MJ, McAdam JJ, McLoughlin A, Quinn T, Watkins CL. Callers' experiences of making emergency calls at the onset of acute stroke: a qualitative study. Emergency Medicine Journal 2012, 29, 502-505.
• Bui C, Barter MJ, Scott JL, Xu Y, Galler M, Reynard LN, Rowan AD, Young DA. cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. FASEB Journal 2012, 26(7), 3000-3011.
• Mukaetova-Ladinska EB, Purshouse K, Andrade J, Krishnan M, Jagger C, Kalaria RN. Can healthy lifestyle modify risk factors for dementia? Findings from a pilot community-based survey in Chennai (India) amd Newcastle (UK). Neuroepidemiology 2012, 39(3), 163-170.
• Collerton J, Yousaf F, Kingston A, Kenny A, Davies K, Robinson L, Kirkwood T, Keavney B. Cardiac dysfunction among the community dwelling very old. In: GSA 65th Annual Scientific Meeting. 2012, San Diego, California, USA: Oxford University Press.
• Bates MGD, Bourke JP, Giordano C, d'Amati G, Turnbull DM, Taylor RW. Cardiac involvement in mitochondrial DNA disease: clinical spectrum, diagnosis, and management. European Heart Journal 2012, 33(24), 3023-3033.
• Willis TA, Hollingsworth KG, Dixon BJ, MacGowan GA, Blamire AM, Straub V. Cardiac MRI in LGMD2I patients. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Hallsworth K, Hollingsworth KG, Thoma C, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. In: 47th Annual Meeting of the European Association for the Study of the Liver (EASL). 2012, Barcelona, Spain: Elsevier BV.
• Hollingsworth KG, Macgowan GA, Morris L, Bates MG, Taylor R, Jones DE, Newton JL, Blamire AM. Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study. Journal of Applied Physiology 2012, 112(12), 2043-2048.
• Hollingsworth KG, Gorman GS, Trenell MI, McFarland R, Taylor RW, Turnbull DM, Macgowan GA, Blamire AM, Chinnery PF. Cardiomyopathy is common in patients with the mitochondrial DNA m.3243A>G mutation and correlates with mutation load. Neuromuscular Disorders 2012, 22(7), 592-596.
• Wang H, Young DA, Cawston TE. Cartilage degradation, expression of mmp-13 and oxidation markers increase with age in the knee joints of aged mice. In: World Congress on Osteoarthritis. 2012, Barcelona, Spain: Elsevier Ltd.
• Lax NZ, Hepplewhite PD, Reeve AK, Nesbitt V, McFarland R, Jaros E, Taylor RW, Turnbull DM. Cerebellar Ataxia in Patients With Mitochondrial DNA Disease: A Molecular Clinicopathological Study. Journal of Neuropathology and Experimental Neurology 2012, 71(2), 148-161.
• Craggs LJL, Yamamoto Y, Watanabe A, Low WC, Slade JY, Attems J, Oakley AE, Kalaria RN. Cerebral Accumulation, Distribution and Clearance of GOM and NOTCH3 fragments in CADASIL. In: 10th European Congress on Neuropathology. 2012, Edinburgh International Conference Centre (EICC), Edinburgh, Scotland, UK.
• Ndung'u M, Hartig W, Wegner F, Mwenda JM, Low RWC, Akinyemi RO, Kalaria RN. Cerebral amyloid beta(42) deposits and microvascular pathology in ageing baboons. Neuropathology and Applied Neurobiology 2012, 38(5), 487-499.
• Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, Kitamura A, Washida K, Yamada M, Ito H, Tomimoto H, Takahashi R, Ihara M. Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts. Acta Neuropathologica 2012, 123(3), 381-394.
• Ratnaike TE, Murphy J, Krishnan KJ, Taylor RW, Turnbull DM. Changes in mitochondrial function over time and with exercise in patients with mitochondrial disease. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Avery L, Flynn D, van-Wersch A, Sniehotta FF, Trenell MI. Changing Physical Activity Behavior in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Behavioral Interventions. Diabetes Care 2012, 35(12), 2681-2689.
• Price C, Rae V, Duckett J, Wood R, McMeekin P, Gray J, Rodgers H, Ford GA. Characteristics of patients according to the mode of admission to regional stroke services. In: UK Stroke Forum 2012 Conference. 2012, Harrogate, UK: Wiley-Blackwell Publishing Asia.
• van der Walt EM, Smuts I, Taylor RW, Elson JL, Turnbull DM, Louw R, van der Westhuizen FH. Characterization of mtDNA variation in a cohort of South African paediatric patients with mitochondrial disease. European Journal of Human Genetics 2012, 20, 650-656.
• Watson R, Blamire AM, Colloby SJ, Wood JS, Barber R, He JB, O'Brien JT. Characterizing dementia with Lewy bodies by means of diffusion tensor imaging. Neurology 2012, 79(9), 906-914.
• Pearce MS, Mann KD, Martin-Ruiz C, Parker L, White M, von Zglinicki T, Adams J. Childhood Growth, IQ and Education as Predictors of White Blood Cell Telomere Length at Age 49-51 Years: The Newcastle Thousand Families Study. PLoS One 2012, 7(7), e40116.
• Watabe Rudolph M, Song Z, Lausser L, Schnack C, Begus Nahrmann Y, Scheithauer MO, Rettinger G, Otto M, Tumani H, Thal DR, Attems J, Jellinger KA, Kestler HA, von Arnim CA, Rudolph KL. Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease. Neurology 2012, 78(8), 569-577.
• Rochester L, Yarnall A, Baker MR, David R, Lord S, Galna B, Burn DJ. Cholinergic dysfunction contributes to gait disturbance in early Parkinson’s disease. Brain 2012, 135(9), 2778-2787.
• Yarnall AJ, Rochester L, David R, Duncan GW, Khoo TK, Barker RA, Brooks DJ, Baker MR, Burn DJ. Cholinergic dysfunction in Parkinson’s disease with mild cognitive impairment: a short latency afferent inhibition study. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Allen J, Murray A, Di Maria C, Newton JL. Chronic fatigue syndrome and impaired peripheral pulse characteristics on orthostasis-a new potential diagnostic biomarker. Physiological Measurement 2012, 33(2), 231-241.
• Maddison J, Straub V, Lochmuller H, Turnbull D, Chinnery P, Trennell M, McFarland R, Gorman G, Horvath R, Busbhy K. Clinical research activity in Newcastle MRC centre. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Campbell GR, Kraytsberg Y, Krishnan KJ, Ohno N, Ziabreva I, Reeve A, Trapp BD, Newcombe J, Reynolds R, Lassmann H, Khrapko K, Turnbull DM, Mahad DJ. Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis. Acta Neuropathologica 2012, 124(2), 209-220.
• Attems J, Alpar A, Spence L, McParland S, Heikenwalder M, Uhlen M, Tanila H, Hokfelt TG, Harkany T. Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation. Proceedings of the National Academy of Sciences 2012, 109(16), 6259-6264.
• Hurt CS, Landau S, Burn DJ, Hindle JV, Samuel M, Wilson K, Brown RG, PROMS-PD Study Grp. Cognition, coping, and outcome in Parkinson's disease. International Psychogeriatrics 2012, 24(10), 1656-1663.
• Frith J, Fattakhova G, Jones DEJ, Henderson E, Wilton K, Day CP, Newton JL. Cognitive impairment in non-cirrhotic chronic liver disease is unrelated to liver disease severity but associated with ineffective baroreflex function. Gut 2012, 61(7), 1101-1103.
• Frith J, Watson S, Maggs PHBB, Newton JL. Cognitive symptoms are common in immune thrombocytopenia and associate with autonomic symptom burden. European Journal of Haematology 2012, 88(3), 224-228.
• Burn DJ. Cognitive testing in the diagnosis of Parkinsonian disorders: A lawn mower for the hare's corner?. Movement Disorders 2012, 27(10), 1201-1202.
• Kirkwood TBL. Commentary: Ageing-what's all the noise about? Developments after Gartner. International Journal of Epidemiology 2012, 41(2), 351-352.
• Zellner M, Baureder M, Rappold E, Bugert P, Kotzailias N, Babeluk R, Baumgartner R, Attems J, Gerner C, Jellinger K, Roth E, Oehler R, Umlauf E. Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimer's disease but not in non-demented Parkinson's disease patients. Journal of Proteomics 2012, 75(7), 2080-2092.
• Jakovljevic DG, Moore S, Hallsworth K, Fattakhova G, Thoma C, Trenell MI. Comparison of cardiac output determined by bioimpedance and bioreactance methods at rest and during exercise. Journal of Clinical Monitoring and Computing 2012, 26(2), 63-68.
• Walker Z, McKeith I, Rodda J, Qassem T, Tatsch K, Booij J, Darcourt J, O'Brien J. Comparison of cognitive decline between dementia with Lewy bodies and Alzheimer's disease: a cohort study. BMJ Open 2012, 2(1), e000380.
• Greaves LC, Elson JL, Nooteboom M, Grady JP, Taylor GA, Taylor RW, Mathers JC, Kirkwood TBL, Turnbull DM. Comparison of Mitochondrial Mutation Spectra in Ageing Human Colonic Epithelium and Disease: Absence of Evidence for Purifying Selection in Somatic Mitochondrial DNA Point Mutations. PLoS Genetics 2012, 8(11), e1003082.
• Bates MGD, Hollingsworth KG, Newman J, Jakovljevic DG, Keavney BD, Blamire AM, MacGowan GA, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. In: Annual Conference of the British Cardiovascular Society (BCS). 2012, Manchester, UK: BMJ Group.
• Bates M, Hollingsworth K, Taylor R, Turnbull D, Trenell MI, Gorman G. Concentric remodeling and increased myocardial torsion in mitochondrial DNA point mutation carriers. In: 61st Annual Scientific Session and Expo of the American College of Cardiology (ACC). 2012, Chicago, Illinois, USA: Elsevier Inc.
• Massey LA, Micallef C, Paviour DC, O'Sullivan SS, Ling HL, Williams DR, Kallis C, Holton JL, Revesz T, Burn DJ, Yousry T, Lees AJ, Fox NC, Jager HR. Conventional Magnetic Resonance Imaging in Confirmed Progressive Supranuclear Palsy and Multiple System Atrophy. Movement Disorders 2012, 27(14), 1755-1762.
• Frederiksen KS, Garde E, Skimminge A, Barkhof F, Scheltens P, van Straaten ECW, Fazekas F, Baezner H, Verdelho A, Ferro JM, Erkinjuntti T, Jokinen H, Wahlund LO, O'Brien JT, Basile AM, Pantoni L, Inzitari D, Waldemar G, LADIS Study Grp. Corpus Callosum Tissue Loss and Development of Motor and Global Cognitive Impairment: The LADIS Study. Dementia and Geriatric Cognitive Disorders 2012, 32(4), 279-286.
• Murphy JL, Ratnaike TE, Shang ES, Falkous G, Blakely EL, Alston CL, Taivassalo T, Haller RG, Taylor RW, Turnbull DM. Cytochrome c oxidase-intermediate fibres: Importance in understanding the pathogenesis and treatment of mitochondrial myopathy. Neuromuscular Disorders 2012, 22(8), 690-698.
• Kalaria RN, Mukaetova-Ladinska EB. Delirium, dementia and senility. Brain 2012, 135(9), 2582-2584.
• Rowan SL, Rygiel K, Purves-Smith FM, Solbak NM, Turnbull DM, Hepple RT. Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle. PLoS One 2012, 7(1), e29082.
• Khoo TK, Duncan GW, Yarnall AJ, Brooks DJ, Barker RA, O'Brien JT, Burn DJ. Depression and anxiety in incident Parkinson’s disease. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Siler U, Jiang Y, Cowley SA, Melguzo D, Tilgner K, Browne C, deWilton A, Pryzborski S, Saretzki G, James WS, Seger RA, Reichenbach J, Lako M, Armstrong L. Derivation and functional analysis of patient specific induced pluripotent stem cells (IPSCS) as an in vitro model of chronic granulomatous disease. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
• Siler U, Jiang Y, Cowley SA, Melguzo D, Tilgner K, Browne C, Dewilton A, Pryzborski S, Saretzki G, James WS, Seger RA, Reichenbach J, Lako M, Armstrong L. Derivation and Functional Analysis of Patient Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease. In: 15th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT). 2012, Philadelphia, Pennsylvania, USA: Nature Publishing Group.
• Avery L, Taylor L, Lievesley M, Mosely K, Speight J, Sniehotta FF, Trenell MI. Development of a behavioural intervention targeting free-living physical activity in adults with type 2 diabetes in primary care: Movement as Medicine. In: Diabetic Medicine: DUK Annual Professional Conference. 2012, Glasgow, UK: Wiley-Blackwell Publishing Ltd.
• Yarnall AJ, Hayes L, Hawthorne GC, Candlish CA, Aspray TJ. Diabetes in care homes: current care standards and residents' experience. Diabetic Medicine 2012, 29(1), 132-135.
• Litvan I, Goldman JG, Troster AI, Schmand BA, Weintraub D, Petersen RC, Mollenhauer B, Adler CH, Marder K, Williams-Gray CH, Aarsland D, Kulisevsky J, Rodriguez-Oroz MC, Burn DJ, Barker RA, Emre M. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Movement Disorders 2012, 27(3), 349-356.
• Yu-Wai-Man P, Gorman GS, Taylor RW, Turnbull DM. Diagnostic investigations of patients with chronic progressive external ophthalmoplegia. British Journal of Ophthalmology 2012, 96(12), 1536-1536.
• Watson R, O'Brien JT. Differentiating dementia with Lewy bodies and Alzheimer’s disease using magnetic resonance imaging. Neurodegenerative Disease Management 2012, 2(4), 411-420.
• Jakovljevic DG, Moore SA, Tan LB, Rochester L, Ford GA, Trenell MI. Discrepancy between cardiac and physical functional reserves in stroke. Stroke 2012, 43, 1422-1425.
• Raftery G, He JB, Pearce R, Birchall D, Newton JL, Blamire AM, Isaacs JD. Disease activity and cognition in rheumatoid arthritis: an open label pilot study. Arthritis Research & Therapy 2012, 14(6), R263.
• Relton CL, Groom A, StPourcain B, Sayers AE, Swan DC, Embleton ND, Pearce MS, Ring SM, Northstone K, Tobias JH, Trakalo J, Ness AR, Shaheen SO, Davey-Smith G. DNA methylation patterns in cord blood DNA and body size in childhood. PLoS One 2012, 7(3), e31821.
• Krishnan KJ, Nelson G, Romero NB, Ratnaike T, Blakely EL, Ziyadeh-Isleem A, Miller J, Murphy JL, Horvath R, Lochmuller H, Flanigan K, Turnbull DM, Guicheney P, Bitoun M, Taylor RW. DNM2 mutations cause multiple mtDNA deletions in muscle: A novel disorder of mtDNA maintenance. In: 17th International Congress of the World Muscle Society (WMS). 2012, Perth, Australia: Elsevier Ltd.
• Burn J, Mathers JC, Bishop DT. Does aspirin really reduce the risk of colon cancer? Reply. Lancet 2012, 379(9826), 1587-1587.
• Kalaria RN, Akinyemi R, Ihara M. Does vascular pathology contribute to Alzheimer changes?. Journal of the Neurological Sciences 2012, 322(1-2), 141-147.
• Howard R, McShane R, Lindesay J, Ritchie C, Baldwin A, Barber R, Burns A, Dening T, Findlay D, Holmes C, Hughes A, Jacoby R, Jones R, Jones R, McKeith I, Macharouthu A, O'Brien J, Passmore P, Sheehan B, Juszczak E, Katona C, Hills R, Knapp M, Ballard C, Brown R, Banerjee S, Onions C, Griffin M, Adams J, Gray R, Johnson T, Bentham P, Phillips P. Donepezil and Memantine for Moderate-to-Severe Alzheimer's Disease. New England Journal of Medicine 2012, 366(10), 893-903.
• McKeith IG. Early diagnosis for Lewy Body Disease and treatment. In: 12th International Stockholm/Springfield Symposium on Advances in Alzheimer Therapy. 2012, Stockholm, Sweden: Elsevier Inc.
• Sivam S, Phillips CL, Trenell MI, Yee BJ, Liu PY, Wong KK, Grunstein RR. Effects of 8 weeks of continuous positive airway pressure on abdominal adiposity in obstructive sleep apnoea. European Respiratory Journal 2012, 40(4), 913-918.
• Curtis P, Adamson A, Mathers J. Effects on nutrient intake of a family-based intervention to promote increased consumption of low-fat starchy foods through education, cooking skills and personalised goal setting: the Family Food and Health Project. British Journal of Nutrition 2012, 107(12), 1833-1844.
• Bosomworth HJ, Thornton JK, Coneyworth LJ, Ford D, Valentine RA. Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis. Metallomics 2012, 4(8), 771-779.
• Duncan GW, Khoo TK, Yarnall AJ, O'Brien JT, Brooks DJ, Barker RA, Burn DJ. Elevated homocysteine levels and cognitive dysfunction in an incident cohort of non-demented Parkinson’s disease patients. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Lindsay S, Jackson D, Ladha C, Ladha K, Brittain K, Olivier P. Empathy, Participatory Design and People with Dementia. In: 30th ACM Conference on Human Factors in Computing Systems (CHI). 2012, Austin, Texas, USA: ACM Press.
• Potter C, Relton CL. Epigenetic Epidemiology. Karin B. Michels (ed). International Journal of Epidemiology 2012, 41(1), 308-309.
• Thathia SH, Ferguson S, Gautrey HE, van Otterdijk SD, Hili M, Rand V, Moorman AV, Meyer S, Brown R, Strathdee G. Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity. Haematologica 2012, 97(3), 371-378.
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