Synthetic Biology, Development and Gene Regulation

Sporulating Bacillus subtilis cells

Movie shows sporulating Bacillus subtilis cells

Bacterial cells need to respond to a wide variety of environmental challenges. To do so, they implement many different adaptive processes, including complex morphological changes such as sporulation and biofilm formation. Several of the signal transduction networks which regulate bacterial developmental processes as well as transcriptomic, proteomic and metabolomics netwroks are studied within the CBCB.

Our unrivalled expertise in the computational design and genetic engineering of various model bacteria makes the CBCB a centre of excellence for synthetic biology. This emerging discipline will be pivotal in our ability to respond to various challenges of the 21st century, for example, in the development of novel biofuels, combating pollution through bioremediation, emerging strategies against antimicrobial resistance and new biomimetic synthetic materials. CBCB hosts the University Research Centre for Synthetic Biology and the Bioeconomy.

The following groups are researching in these areas: