Newcastle University

Qualifications

B.Sc. (Civil Engineering) Glasgow University 1984
B.Sc. Statistics (First Class) Glasgow University 1989
Ph.D. (Statistics) University of Glasgow 1993

Previous Positions

Dean of Research Faculty of Science, Agriculture and Engineering 2003 - 2006

Memberships

Fellow of the Royal Statistical Society 1989
Fellow of the Institute of Chemical Engineering 2004
Chartered Engineer 2004

Honours and Awards

Attendance at Buckingham Palace Reception in recognition of contribution to UK Science and Engineering. 2006

Research Interests

Multivariate Statistics; Bayesian Analysis; Design of Experiments; Empirical based Modelling; Development and application of statistical methodologies to industry facing problems (Bioprocessing, Speciality chemicals, Food & drink)

Research themes:

Esteem Indicators

Chairman of the EPSRC Technical Opportunities Panel 2006 - 2007
Member of EPSRC Council 2006 - 2007
Member of the EPSRC Technical Opportunities Panel 2004 – 2006
Member of the EPSRC Strategic Advisory Team (SAT) for General Engineering 2002 – 2004
Member of the EPSRC/BBSRC Bioprocessing Research Industry Club 2005 -
Member of the EPSRC Engineering Peer Review College 1998 -
Member of the EPSRC Collaborating for Success Through People Panel 2007
Member of the EPSRC Systems Biology Panel 2007
Member of the EPSRC Panel for the Faraday Review 2006
Member of the EPSRC Challenging Engineering Panel 2006
Member of the EPSRC Panel for the Process Engineering and Life Sciences Interface 2006
Chairman EPSRC – Discipline hopping Awards 2005
Member of the EPSRC Portfolio Partnership Awards Panel 2004, 2005
Chairman EPSRC Advanced Fellowships Panel (Mathematics) 2005
Member of the EPSRC Advanced Fellowship Panel 2004
Chairman EPSRC Large Multi-Disciplinary Mathematics Panel 2003
Chairman EPSRC Responsive Mode Panel – Systems Panel 2003
Member of the EPSRC Novel Computation Initiative – Six Month Cluster Panel 2004
Member of the EPSRC Engineering Evaluation Panel. 2002
Member of the EPSRC Large Multi-Disciplinary Mathematics Panel (twice)2002
Chairman (twice) and Member (three) of EPSRC Responsive Mode Panel C 1999 -
Member of the EPSRC Engineering International Collaboration Panel 2002
Member of the BBSRC Review Panel for Engineering and Biological Sciences 2007
Member of BBSRC Working Group on Synthetic Biology 2006 -
Member of the European Science Foundation Standing Group for Physical and Engineering Sciences 2006 -
Member of the European Science Foundation Core Group for Physical and Engineering Sciences 2006 -
PESC liaison to the COST DC BMBS (Biomedicine and Molecular Biosciences) 2007 -
Member of the Academic Board of the Chemical Innovations Knowledge Transfer Network 2006 -
Member of the RAE Sub-Panel (Mechanical, Aeronautical and Manufacturing Engineering) 2005 -
Member of the Advisory Board of the Research Information Network 2005 -
Chair of the Research Information Network Physical Sciences consultative group 2005 -
Member of the Expert Panel on Researchers Use of Academic Libraries and their Services 2006
Member of Scientific Steering Committee Isaac Newton Institute for Mathematical Sciences, University of Cambridge 2004 - 2007
Director of Neural Computing Applications Forum 2003 - 2006
Chairman of External Advisory Board, Department of Engineering Mathematics, University of Bristol 2006 -

Funding

EPSRC “Process 2020 Innovation SatVav”, Value to Newcastle University, £440,000. Principal Investigator, E. Martin. Co-Investigator, G. Montague. Newcastle University, Manchester University, Reading University and York University. Companies involved GSK, Johnson Mathey and Robinson Brothers. Awarded January 2007.

EPSRC “Can Understanding the Emergent Behaviour of Mixed Culture Systems Aid in Wastewater Treatment System Design and Operation”, Value to Newcastle University, £160,000. Principal Investigator, G. Montague, Co- Investigator, E. Martin, T. Curtis, I. Head and J. Dofling. Awarded January 2007.

EPSRC/CIKTN Case Award “Multi-Metric based Decision Making in Whole Process Design” Value to Newcastle University, £80,000. Principal Investigator, G. Montague, Co- Investigator, E. Martin Awarded May 2007.

DTI Minimising the Environmental Footprint of FMCG Plant Improved Cleaning Processes, Value to Newcastle University, £482,193. Principal Investigator, E. Martin. Co-Investigator, G. Montague. Newcastle University, Birmingham University and Imperial College. Companies involved Unilever, Cadbury, GSK and Scottish and Newcastle, Bruker, Alfa Lavel, GEA and Ecolab. Awarded September 2006.

DTI Succeeding through Innovation. Implementing PAT for successful development of Biopharmaceuticals in the UK. Principal Investigator, G. Montague. Co-Investigator, E. Martin. Value to Newcastle University £398,792. Strathclyde University, Liverpool University and Newcastle University, Company involved, GlaxoSmithKline. Awarded August 2006.

KTP with Avecia Biologics “To develop a statistical framework to assist in the progression of bio-process design and process scale-up.” Value to Newcastle University £99,044. Awarded December 2006.

Industrial Relevance

Consultancy

Specialist Expertise
The primary area that I undertake consultancy into is that of industrial statistics. More specifically the areas include:
The application of statistical tools for the analysis of industrial data (including bioprocess, chemical, speciality chemicals), Experimental design,
Statistical process control,
Multivariate process monitoring,
Process modelling (different regression analysis approaches).

Projects

• Implementing PAT for successful development of Biopharmaceuticals in the UK
  Project Leader(s): Prof Gary Montague
• Minimising the Environmental Footprint of FMCG Plant Improved Cleaning Processes
  Project Leader(s): Prof Elaine Martin
• Process 2020 Innovation SatNav
  Project Leader(s): Prof Elaine Martin

• Chen T, Morris J, Martin E. Gaussian process regression for multivariate spectroscopic calibration. Chemometrics and Intelligent Laboratory Systems 2007, 87(1), 85-97.
• Chen T, Morris J, Martin E. Particle filters for state and parameter estimation in batch processes. Journal of Process Control 2005, 15(6), 665-673.
• Sang WC, Martin EB, Morris AJ, Lee I-B. Fault detection based on a maximum-likelihood principal component analysis (PCA) mixture. Industrial and Engineering Chemistry Research 2005, 44(7), 2316-2327.
• Meng X, Morris AJ, Martin EB. On-line monitoring of batch processes using a PARAFAC representation. Journal of Chemometrics 2003, 17(1), 65-81.
• Simoglou A, Martin EB, Morris AJ. Statistical performance monitoring of dynamic multivariate processes using state space modelling. Computers and Chemical Engineering 2002, 26(6), 909-920.
• Chen Z-P, Morris J, Martin E. Correction of temperature-induced spectral variations by loading space standardization. Analytical Chemistry 2005, 77(5), 1376-1384.
• Yang A, Morris J, Montague G, Martin E. Determination of operating regimes for chemical reactors using incomplete mechanistic knowledge and a mutual information-based dependency test. Industrial and Engineering Chemistry Research 2007, 46(10), 3390-3399.
• Chen T, Morris J, Martin E. Dynamic data rectification using particle filters. Computers & Chemical Engineering 2008, 32(3), 451-462.
• Triadaphillou S, Martin E, Montague G, Norden A, Jeffkins P, Stimpson S. Fermentation process tracking through enhanced spectral calibration modeling. Biotechnology and Bioengineering 2007, 97(3), 554-567.
• Yang A, Montague G, Martin EB. Importance of heterogeneous energy dissipation in the modeling and optimization of batch cooling crystallization. Industrial and Engineering Chemistry Research 2007, 46(22), 7177-7187.
• Chen T, Morris J, Martin E. Probability density estimation via an infinite Gaussian mixture model: Application to statistical process monitoring. Journal of the Royal Statistical Society. Series C: Applied Statistics 2006, 55(5), 699-715.
• Li B, Hassel PA, Morris AJ, Martin EB. A non-linear nested partial least-squares algorithm. Computational Statistics and Data Analysis 2005, 48(1), 87-101.
• Thennadil SN, Martin EB. Empirical preprocessing methods and their impact on NIR calibrations: A simulation study. Journal of Chemometrics 2005, 19(2), 77-89.
• Chen ZP, Morris J, Martin E, Hammond RB, Lai X, Ma C, Purba E, Roberts KJ, Bytheway R. Enhancing the signal-to-noise ratio of X-ray diffraction profiles by smoothed principal component analysis. Analytical Chemistry 2005, 77(20), 6563-6570.
• Simoglou A, Georgieva P, Martin EB, Morris AJ, Feyo De Azevedo S. On-line monitoring of a sugar crystallization process. Computers and Chemical Engineering 2005, 29(6), 1411-1422.
• Martin EB, Montague GA, Robbins P. A quality by design approach to process plant cleaning. Chemical Engineering Research and Design 2013, (epub ahead of print).
• Mead EJ, Chiverton LM, Spurgeon SK, Martin EB, Montague GA, Smales CM, von der Haar T. Experimental and In Silico Modelling Analyses of the Gene Expression Pathway for Recombinant Antibody and By-Product Production in NS0 Cell Lines. PLoS One 2012, 7(10), e47422.
• Lang D, Martin EB, Montague GA, O'Malley CJ, Root TS, Trim CM, Povey JF, Smales CM, Racher AJ. Rapid Method for Targeted Cell (Line) Selection. WO 2012/055554 A1, 3 May 2012.
• O'Malley CJ, Montague GA, Martin EB, Liddell J, Kara B, Titchener-Hooker NJ. Utilisation of Key Descriptors from Protein Sequence Data to Aid BIOProcess Route Selection. Food and Bioproducts Processing 2012, 90(4), 755-761.
• Yang AD, Martin E, Morris J. Identification of semi-parametric hybrid process models. Computers & Chemical Engineering 2011, 35(1), 63-70.
• Xu AP, Dolfing J, Curtis TP, Montague G, Martin E. Maintenance affects the stability of a two-tiered microbial 'food chain'?. Journal of Theoretical Biology 2011, 276(1), 35-41.
• Martin EB, Montague G, Jones B. The Academic Industry Model for Doctoral Training. In: 2nd International Conference on Professional Doctorates. 2011, John McIntyre Conference Centre, Edinburgh: UK Council for Graduate Education.
• Martin EB, Montague G, Jones B, Symmington J. Biopharmaceutical and Bioprocessing Technology at Newcastle University. In: DOC CAREERS II 1st Workshop. 2010, Dublin, Ireland: European University Association.
• Manipura A, Sharratt P, Roberts E, Martin E, Montague G, Housan I, Fernandes K. A decision support system for synthetic route selection in pharmaceutical development. In: AIChE Annual Meeting, Conference Proceedings. 2009, Nashville, Tennessee, USA.
• Jiang C, Martin EB. Functional data analysis for the development of a calibration model for near-infrared data. In: 18th European Symposium on Computer Aided Process Engineering (ESCAPE 18). 2008, Lyon, France: Computer Aided Chemical Engineering: Elsevier BV.
• Yang A, Martin EB, Montague GA, Fryer PJ. Towards improved cleaning of FMCG plants: a model-based approach. In: 18th European Symposium on Computer Aided Process Engineering (ESCAPE 18). 2008, Lyon, France: Computer Aided Chemical Engineering: Elsevier BV.
• Chen Y, Morris J, Martin E. Response to the discussion of Gaussian process regression for multivariate spectroscopic calibration. Chemometrics and Intelligent Laboratory Systems 2007, 87(1), 69-71.
• Yang A, Martin E, Montague G, Morris J. Optimal experimental design for the precision of a subset of model parameters in process development. Computer Aided Chemical Engineering 2006, 21(C), 563-568.
• Chen T, Morris J, Martin E. Bayesian control limits for statistical process monitoring. In: International Conference on Control and Automation (ICCA). 2005, Budapest, Hungary: IEEE.
• Triadaphillou S, Martin E, Montague G, Jeffkins P, Stimpson S, Nordon A. Enhanced modeling of an industrial fermentation process through data fusion techniques. Computer Aided Chemical Engineering 2005, 20(C), 1393-1398.
• Triadaphillou S, Martin E, Montague G, Jeffkins P, Stimpson S, Nordon A. Enhanced modeling of an industrial fermentation process through data fusion techniques. In: 15th European Symposium on Computer Aided Process Engineering (ESCAPE-15). 2005, Barcelona, Spain: Elsevier BV.
• Alawi A, Morris A, Martin E. Statistical performance monitoring using state space modelling and wavelet analysis. Computer Aided Chemical Engineering 2005, 20(C), 1459-1464.
• Wong C, Escott R, Morris A, Martin E. The integration of process and spectroscopic data for enhanced knowledge extraction in batch processes. Computer Aided Chemical Engineering 2005, 20(C), 1141-1146.
• Musicka T, Morris J, Martin E, Kitson P. A framework for data analysis and modelling - industrial case study at Corus UK Plc. In: 5th International Conference on Quality, Reliability and Maintenance. 2004, Oxford, UK: Professional Engineering Publishing.
• Novakovic K, Morris J, Martin E. Mathematical analysis of the formation of molecule sizes on a spinning disc reactor. In: 8th Pacific Polymer Conference. 2004, Bangkok, Thailand: Wiley-Blackwell Publishing.
• Bezas K, Farrugia D, Richardson A, Musicka T, Zhang J, Martin EB. Modelling the distortion of long product sections after hot rolling using finite elements and neural networks. In: 5th International Conference on Quality, Reliability, and Maintenance (QRM 2004). 2004, Oxford, UK: Professional Engineering Publishing.
• Simoglou A, Georgieva P, Martin E, Morris A, Feyo de Azevedo S. On-line multivariate statistical monitoring of a fed-batch sugar crystallisation process. Computer Aided Chemical Engineering 2004, 18(C), 817-822.
• Chen T, Morris J, Martin E. Particle filters for the estimation of a state space model. Computer Aided Chemical Engineering 2004, 18(C), 613-618.
• Chen T, Morris J, Martin E. Particle filters for the estimation of a state space model. In: 14th European Symposium on Computer Aided Process Engineering (ESCAPE). 2004, Lisbon, Portugal: Elsevier BV.
• Novakovic K, Boodhoo KVK, Martin EB, Morris AJ. Data Analysis and Modelling of Spinning Disc Polymerisation from Minimal Data. In: First International Symposium on Process Intensification and Miniaturisation. 2003, Newcastle upon Tyne, UK.
• Novakovic K, Martin EB, Morris AJ. Modelling of Kinetics of Free Radical Polymerisation on Spinning Disc Reactor. In: Polymer Reaction Engineering: Modelling, Optimisation and Control. 2003, Lyon, France.
• Novakovic K, Martin EB, Morris AJ. Modelling of the Free Radical Polymerization of Styrene with Benzoyl Peroxide as Initiator. In: European Symposium on Computer Aided Process Engineering-13: 36th European Symposium of the Working Party on Computer Aided Process Engineering. 2003, Lappeenranta, Finland: Computer Aided Chemical Engineering: Elsevier BV.
• Novakovic K, Martin EB, Morris AJ. Modelling of the free radical polymerization of styrene with benzoyl peroxide as initiator. In: 13th European Symposium on Computer Aided Process Engineering (ESCAPE). 2003, Lappeenranta, Finland: Elsevier BV.
• Montague GA, Martin EB, Morris AJ. On-line analysis and control of product quality. In: Tothill, I, ed. Rapid and On-line Instrumentation for Food Quality Assurance. Cambridge, UK: Woodhead Publishing Ltd, 2003, pp.371-404.
• Li B, Martin EB. An approximation to the F distribution using the chi-square distribution. Computational Statistics and Data Analysis 2002, 40(1), 21-26.
• Lu Z, Martin E, Morris J. Bayesian parameter estimation in batch polymerisation. In: 12th European Symposium on Computer Aided Process Engineering (ESCAPE-12). 2002, The Hague, The Netherlands: Computer Aided Chemical Engineering: Elsevier BV.
• Fletcher N, Morris A, Martin E. Comparison of dynamic approaches for batch monitoring. In: 12th European Symposium on Computer Aided Process Engineering (ESCAPE-12). 2002, The Hague, The Netherlands: Computer Aided Chemical Engineering: Elsevier BV.
• Kumar S, Martin EB, Morris J. Detection of process model changes in PCA based performance monitoring. In: Proceedings of the American Control Conference. 2002, Anchorage, Alaska: American Automatic Control Council.
• Martin EB, Morris AJ. Enhanced bio-manufacturing through advanced multivariate statistical technologies. Journal of Biotechnology 2002, 99(3), 223-235.
• Martin EB, Bettoni A, Morris AJ. Manufacturing Performance Monitoring of a Mixed Batch Continuous Process through Resampling. Journal of Quality Technology 2002, 34(2), 171-186.
• Martin EB, Bettoni A, Morris AJ. Monitoring of a batch continuous process using mass re-sampling. Journal of Quality Technology 2002, 34(2), 171-186.
• Baffi G, Morris J, Martin E. Non-linear model based predictive control through dynamic non-linear partial least squares. Chemical Engineering Research & Design 2002, 80(A1), 75-86.
• Mercer E, Martin E, Morris A. State-space residual based monitoring. In: Computer Aided Chemical Engineering. 2002, The Hague, The Netherlands: Computer Aided Chemical Engineering: Elsevier BV.
• Musicka T, Martin E, Morris J, Kitson P. Steel processing using a Bayesian adaptive network. In: Quality, Reliability and Maintenance (QRM). 2002, Oxford, UK: Wiley.
• McPherson L, Morris J, Martin E. Super model-based techniques for batch performance monitoring. In: 12th European Symposium on Computer Aided Process Engineering (ESCAPE-12). 2002, The Hague, The Netherlands: Computer Aided Chemical Engineering: Elsevier BV.
• Wise BM, Gallagher NB, Martin EB. Application of PARAFAC2 to fault detection and diagnosis in semiconductor etch. Journal of Chemometrics 2001, 15(4), 285-298.
• Wise BM, Gallagher NB, Martin EB. Application of PARAFAC2 to fault detection and diagnosis in semiconductor etch. Journal of Chemometrics 2001, 15(4), 285-298.
• Kaskavelis E, Martin E, Jonathan P, Morris J. Statistical analysis of catalyst degradation in a semi-continuous chemical production process. Journal of Chemometrics 2001, 15(8), 665-683.
• Weighell M, Martin EB, Morris AJ. The statistical monitoring of a complex manufacturing process. Journal of Applied Statistics 2001, 28(3-4), 409-425.
• Meng X, Martin E, Morris A. A comparative study of Bi-linear and tri-linear approaches for the monitoring of an industrial batch process. In: 10th European Symposium of Computer Aided Process Engineering (ESCAPE-10). 2000, Florence, Italy: Computer Aided Chemical Engineering: Elsevier BV.
• Conlin AK, Martin EB, Morris AJ. Confidence limits for contribution plots. In: Proceedings of the SSC6, August 1999, HiT/TF. 2000, Porsgrunn, Norway: John Wiley & Sons.
• Lane S, Martin EB, Morris AJ. Monitoring of a dynamic manufacturing process. In: Control Systems, Preprints, Conference. 2000.
• Simoglou A, Martin EB, Morris AJ. Multivariate statistical process control of an industrial fluidised-bed reactor. Control Engineering Practice 2000, 8(8), 893-909.
• Li E, Martin E, Morris A. Non-linear partial least squares through data transformations. In: 10th European Symposium of Computer Aided Process Engineering (ESCAPE-10). 2000, Florence, Italy: Computer Aided Chemical Engineering: Elsevier BV.
• Lane S, Martin EB, Morris AJ. On-line monitoring of multiple grade production. In: Control Systems, Preprints, Conference. 2000.
• Simoglou A, Martin EB, Morris AJ. Comparison of Canonical Variate Analysis and Partial Least Squares for the identification of dynamic processes. In: Proceedings of the American Control Conference. 1999, San Diego, CA , USA: IEEE.
• Simoglou A, Martin EB, Morris AJ. Dynamic multivariate statistical process control using partial least squares and canonical variate analysis. In: European Symposium on Computer Aided Process Engineering-9. 1999, Budapest, Hungary: Pergamon.
• Bissessur Y, Martin EB, Morris AJ. Machine condition monitoring for consistent paper production. Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical 1999, 213(3), 141-151.
• Bissessur Y, Martin EB, Morris AJ. Monitoring the performance of the paper making process. Control Engineering Practice 1999, 7(11), 1357-1368.