Publication:

Nucleoside Transport Inhibitors: Structure-Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of alpha(1)-Acid Glycoprotein (2011)

Author(s): Saravanan K, Barlow HC, Barton M, Calvert AH, Golding BT, Newell DR, Northen JS, Curtin NJ, Thomas HD, Griffin RJ

      • Date: 02-03-2011
      • Journal: Journal of Medicinal Chemistry
      • Volume: 54
      • Issue: 6
      • Pages: 1847-1859
      • Publisher: American Chemical Society
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: PHASE-I TRIAL THYMIDYLATE SYNTHASE CANCER-CELLS MULTITARGETED ANTIFOLATE DIPYRIDAMOLE ANALOGS GROWTH-INHIBITION DRUG ACTIVITY METHOTREXATE IDENTIFICATION THYMIDINE

      Staff

      Professor Bernard Golding
      Senior Research Investigator

      Professor Roger Griffin
      Professor of Medicinal Chemistry