Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase (2007)

Author(s): Hollick J, Rigoreau L, Cano-Soumillac C, Cockcroft X, Curtin NJ, Frigerio M, Golding BT, Guiard S, Hardcastle IR, Hickson I, Hummersone M, Menear K, Martin N, Matthews I, Newell DR, Ord R, Richardson C, Smith G, Griffin RJ

      • Journal: Journal of Medicinal Chemistry
      • Volume: 50
      • Issue: 8
      • Pages: 1958-1972
      • Publication type: Article
      • Bibliographic status: Published

      Dr Celine Cano
      Senior Lecturer in Medicinal Chemistry

      Professor Bernard Golding
      Senior Research Investigator

      Dr Ian Hardcastle
      Reader in Medicinal Chemistry