Publication:

Selective benzopyranone and pyrimido[2,1-alpha]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: Synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro (2005)

Author(s): Griffin RJ, Fontana G, Golding BT, Guiard SL, Hardcastle IR, Leahy JJJ, Martin N, Richardson C, Rigoreau LJM, Stockley ML, Smith GCM

      • Date: 29-12-2004
      • Journal: Journal of Medicinal Chemistry
      • Volume: 48
      • Issue: 2
      • Pages: 569-585
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT WORTMANNIN LY294002 REPAIR DAMAGE P53 KU PHOSPHORYLATION REQUIREMENT

      Staff

      Professor Bernard Golding
      Senior Research Investigator

      Professor Roger Griffin
      Professor of Medicinal Chemistry