Deputy Head of the School of Chemistry
Director of Excellence in Learning and Teaching
Degree Programme Director for BSc Natural Sciences
Degree Programme Director for MSc Drug Chemistry
My career began with a PhD at Leeds University where I worked with Dr David W Jones on an investigation into the mechanism of a norbornadiene rearrangement. I then worked with Professor Richard C Cookson at Southampton University on large ring synthesis using pericyclic reactions. This was followed by a year working with Professor BT Golding at Newcastle, where we embarked upon an investigation into the mechanism of toxicity of vinyl chloride.
My current research interests are focused on exploring reactivity in processes of biological significance. Projects include mechanisms of sensitisation by dialdehydes and anhydrides, reactions of the mycotoxin patulin, and, in a collaboration with Bernard Golding, we are looking at the metabolic fate of benzene and 1,3-butadiene and reactions of metabolites with peptides and DNA.