I work in Thomas von Zglinicki's lab at the Centre for Integrated Systems Biology of Ageing and Nutrition (CISBAN), within Newcastle University Institute for Ageing.
My research background has covered areas as diverse as filamentous fungi through to mammalian tissues. The overarching interest which bridges these different models is attempting to understand intracellular signalling networks.
BSc and PhD from Edinburgh University
Postdoc with Astrazeneca and Liverpool University, followed by a postdoc at Liverpool University.
BSRA (British Society for Research on Ageing)
My research is focussed on the signalling networks involved in induction and maintenance of eukaryotic cellular senescence.
For my work I predominantly use fluorescence microscopy, specifically live cell, timelapse imaging. For this I develop and create fluorescent fusion proteins which can report activation of signalling pathways and /or intracellular phenotoypic changes.
My recent work has focussed on changes in DNA damage induction and repair in senescence.
Predominantly microscopy and molecular biology. I also maintain several widefield microscopes and a confocal research microscope, which are used by a large group of researchers for immunohistochemistry, immunocytochemistry, immunofluorescence and live cell timelapse fluorescence imaging.