Our research aims to develop an understanding of the biology of ageing and ageing-related diseases using a systems approach. The way nutrients are used by the body and what nutrients are consumed have been implicated as major influences on longevity.
However, there are multiple causes and mechanisms of ageing. Each mechanism may make only a modest contribution to the whole. By taking a systems-wide approach, CISBAN seeks to capture the whole picture of what drives the ageing process, not simply a limited view of the contributing factors.
In addition to traditional and high throughput laboratory techniques, CISBAN uses a number of modelling and software systems. Very large amounts of data are generated through a range of experimental studies and analysed in silico. This process provides a highly dynamic cycle of interaction between theoretical and experimental activity.
Our primary areas of research are: