Project:
Incorporating dataset relevance into functional networks
Project Leader(s): Jennifer Hallinan, Anil Wipat
Staff: Katherine James (former member)
Probabilistic integrated functional networks (PFINs) are widely used in systems biology to investigate the interactions between genes, gene products and other biomolecules.
Different experiment types produce different information about these interactions. This project aims to exploit the biases in different data sets by using them to highlight interactions of relevance to a particular biological question. We have generated and analysed networks relevant to ageing and telomere maintenance for Homo sapiens and Saccharomyces cerevisiae.
Current research is focussed upon comparing and analysing particularly relevant subnetworks from different species.
For more information contact:
Jennifer Hallinan
email: j.s.hallinan@ncl.ac.uk
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Professor Anil Wipat
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