Newcastle University

Publications

Year: 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981

• Pezze PD, Sonntag AG, Thien A, Prentzell MT, Godel M, Fischer S, Neumann-Haefelin E, Huber TB, Baumeister R, Shanley DP, Thedieck K. A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation. Science Signaling 2012, 5(217), ra25.
• Sonntag AG, Dalle-Pezze P, Shanley DP, Thedieck K. A modelling-experimental approach reveals IRS dependent regulation of AMPK by Insulin. FEBS Journal 2012, (epub ahead of print).
• Nakjang S, Ndeh DA, Wipat A, Bolam DN, Hirt RP. A novel extracellular metallopeptidase domain shared by animal host-associated mutualistic and pathogenic microbes. PLoS One 2012, 7(1), e30287.
• Craig K, Young MJ, Blakely EL, Longley MJ, Turnbull DM, Copeland WC, Taylor RW. A p.R369G POLG2 mutation associated with adPEO and multiple mtDNA deletions causes decreased affinity between polymerase gamma subunits. Mitochondrion 2012, 12(2), 313-319.
• Lawless C, Jurk D, Gillespie CS, Shanley D, Saretzki G, von Zglinicki T, Passos JF. A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations. PLoS One 2012, 7(2), e32117.
• Stephan BC, Matthews FE, Ma B, Muniz G, Hunter S, Davis D, McKeith IG, Foster G, Ince PG, Brayne C. Alzheimer and Vascular Neuropathological Changes Associated with Different Cognitive States in a Non-Demented Sample. Journal of Alzheimer's Disease 2012, 29(2), 309-318.
• Kofler BM, Miles EA, Curtis P, Armah CK, Tricon S, Grew J, Napper FL, Farrell L, Lietz G, Packard CJ, Caslake MJ, Mathers JC, Williams CM, Calder PC, Minihane AM. Apolipoprotein E genotype and the cardiovascular disease risk phenotype: Impact of sex and adiposity (the FINGEN study). Atherosclerosis 2012, 221(2), 467-470.
• Weile J, James K, Hallinan J, Cockell SJ, Lord P, Wipat A, Wilkinson DJ. Bayesian integration of networks without gold standards. Bioinformatics 2012, (epub ahead of print).
• Lax NZ, Hepplewhite PD, Reeve AK, Nesbitt V, McFarland R, Jaros E, Taylor RW, Turnbull DM. Cerebellar Ataxia in Patients With Mitochondrial DNA Disease: A Molecular Clinicopathological Study. Journal of Neuropathology and Experimental Neurology 2012, 71(2), 148-161.
• van der Walt EM, Smuts I, Taylor RW, Elson JL, Turnbull DM, Louw R, van der Westhuizen FH. Characterization of mtDNA variation in a cohort of South African paediatric patients with mitochondrial disease. European Journal of Human Genetics 2012, (epub ahead of print).
• Rowan SL, Rygiel K, Purves-Smith FM, Solbak NM, Turnbull DM, Hepple RT. Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle. PLoS One 2012, 7(1), e29082.
• Jiang Y, Cowley SA, Siler U, Melguizo D, Tilgner K, Browne C, Dewilton A, Przyborski S, Saretzki G, James WS, Seger RA, Reichenbach J, Lako M, Armstrong L. Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease. Stem Cells 2012, 30(4), 599-611.
• Howard R, McShane R, Lindesay J, Ritchie C, Baldwin A, Barber R, Burns A, Dening T, Findlay D, Holmes C, Hughes A, Jacoby R, Jones R, Jones R, McKeith I, Macharouthu A, O'Brien J, Passmore P, Sheehan B, Juszczak E, Katona C, Hills R, Knapp M, Ballard C, Brown R, Banerjee S, Onions C, Griffin M, Adams J, Gray R, Johnson T, Bentham P, Phillips P. Donepezil and Memantine for Moderate-to-Severe Alzheimer's Disease. New England Journal of Medicine 2012, 366(10), 893-903.
• Mathers J, Curtis P, Adamson A. Effects on nutrient intake of a family-based intervention to promote increased consumption of low-fat starchy foods through education, cooking skills and personalised goal setting: the Family Food and Health Project. British Journal of Nutrition 2012, (epub ahead of print).
• Thathia SH, Ferguson S, Gautrey HE, van Otterdijk SD, Hili M, Rand V, Moorman AV, Meyer S, Brown R, Strathdee G. Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity. Haematologica 2012, 97(3), 371-378.
• Rashidi A, Kirkwood TBL, Shanley DP. Evolution of Asymmetric Damage Segregation: A Modelling Approach. In: Breitenbach, M., Jazwinski, S.M. Laun, P, ed. Aging Research in Yeast. Berlin; New York: Springer, 2012, pp.315-330.
• Jones D, Stephens S, Yates L, Dunstan H, Richardson JL, Greenall A, Thomas SHL. Fetal Outcomes Following Fentanyl Exposure in Pregnancy. In: International Congress of the European Association of Poisons Centres and Clinical Toxicologists. 2012, London, UK: Informa Healthcare.
• Gorowiec MR, Borthwick LA, Parker SM, Kirby JA, Saretzki GC, Fisher AJ. Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-beta 1-dependent mechanism. Free Radical Biology & Medicine 2012, 52(6), 1024-1032.
• McKay JA, Groom A, Potter C, Coneyworth LJ, Ford D, Mathers JC, Relton CL. Genetic and Non-Genetic Influences during Pregnancy on Infant Global and Site Specific DNA Methylation: Role for Folate Gene Variants and Vitamin B₁₂. PLoS One 2012, 7(3), e33290.
• Pearce MS, McConnell JC, Barrett LM, Mathers JC, Parker L, Relton CL. Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles. International Journal of Epidemiology 2012. In Press.
• Keage HAD, Ince PG, Matthews FE, Wharton SB, McKeith IG, Brayne C, MRC CFAS CC75C. Impact of Less Common and "Disregarded" Neurodegenerative Pathologies on Dementia Burden in a Population-Based Cohort. Journal of Alzheimer's Disease 2012, 28(2), 485-493.
• Taylor J-P, Firbank M, He J, Barnett N, Pearce S, Livingstone A, Vuong Q, McKeith IG, O'Brien JT. Investigation of the visual cortex in dementia with Lewy bodies using magnetic resonance imaging. British Journal of Psychiatry 2012. In Press.
• Lax NZ, Campbell GR, Reeve AK, Ohno N, Zambonin J, Blakely EL, Taylor RW, Bonilla E, Tanji K, DiMauro S, Jaros E, Lassmann H, Turnbull DM, Mahad DJ. Loss of Myelin-Associated Glycoprotein in Kearns-Sayre Syndrome. Archives of Neurology 2012, 69(4), 490-499.
• Greaves LC, Reeve AK, Taylor RW, Turnbull DM. Mitochondrial DNA and disease. Journal of Pathology 2012, 226(2), 274-286.
• Passos JF, von Zglinicki T. Mitochondrial dysfunction and cell senescence - skin deep into mammalian aging. Aging 2012, 4(2), 74-75.
• Gillespie CS, Milner P, Wilkinson DJ. Moment closure based parameter inference of stochastic kinetic models. Statistics and Computing 2012, (epub ahead of print).
• Stephan BC, Matthews FE, Hunter S, Savva GM, Bond J, McKeith IG, Ince P, Brayne C, Medical Research Council Cognitive Function and Ageing Study. Neuropathological Profile of Mild Cognitive Impairment from a Population Perspective. Alzheimer Disease and Associated Disorders 2012, (epub ahead of print).
• Dang TS, Walker M, Ford D, Valentine R. Nutrigenetics and Nutrigenomics; the role of nutrition in gene expression. Periodontology 2000 2012. In Preparation.
• Groom A, Potter C, Swan DC, Fatemifar G, Evans DM, Ring SM, Turcot V, Pearce MS, Embleton ND, Smith GD, Mathers JC, Relton CL. Postnatal Growth and DNA Methylation Are Associated With Differential Gene Expression of the TACSTD2 Gene and Childhood Fat Mass. Diabetes 2012, 61(2), 391-400.
• Read JL, Whittaker RG, Miller N, Clark S, Taylor R, McFarland R, Turnbull D. Prevalence and severity of speech and swallowing difficulties in mitochondrial disease. International Journal Language Communication Disorders 2012, 47(1), 106-111.
• Reeve AK, Park TK, Jaros E, Campbell GR, Lax NZ, Hepplewhite PD, Krishnan KJ, Elson JL, Morris CM, McKeith IG, Turnbull DM. Relationship Between Mitochondria and α-Synuclein: A Study of Single Substantia Nigra Neurons. Archives of Neurology 2012, 69(3), 385-393.
• Lax NZ, Whittaker RG, Hepplewhite PD, Reeve AK, Blakely EL, Jaros E, Ince PG, Taylor RW, Fawcett PR, Turnbull DM. Sensory neuronopathy in patients harbouring recessive polymerase γ mutations. Brain 2012, 135(1), 62-71.
• Dewar JM, Lydall D. Similarities and differences between "uncapped" telomeres and DNA double-strand breaks. Chromosoma 2012, 121(2), 117-130.
• Lietz G, Oxley A, Leung W, Hesketh J. Single Nucleotide Polymorphisms Upstream from the beta-Carotene 15,15 '-Monoxygenase Gene Influence Provitamin A Conversion Efficiency in Female Volunteers. Journal of Nutrition 2012, 142(1), 161S-165S.
• Gillespie CS. Stochastic simulation of chemically reacting systems using multi-core processors. Journal of Chemical Physics 2012, 136(1), 014101.
• Hewitt G, Jurk D, Marques FDM, Correia-Melo C, Hardy T, Gackowska A, Anderson R, Taschuk M, Mann J, Passos JF. Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Nature Communications 2012, 3, 708.
• Killen AJ, Firbank MJ, Collerton D, Clarke MP, Jeffries J, Taylor J-P, McKeith IG, Mosimann U. The assessment of cognition in visually impaired older adults. Age and Ageing 2012. In Press.
• Heighton C, Moffatt S, Howel D, McColl E, Milne E, Deverill M, Rubin G, Aspray T, White M. The Do-Well Study :Protocol for a randomised control trial, economic and qualitative process evaluations of domiciliary welfare rights advice for socio-economically disadvantaged older people recruited via primary health care. BMC Public Health 2012. In Press.
• Collerton J, Kingston A, Bond J, Davies K, Eccles MP, Jagger C, Kirkwood TBL, Newton JL. The Personal and Health Service Impact of Falls in 85 Years Olds: Cross-Sectional Findings from the Newcastle 85+ Cohort Study. PLoS One 2012, 7(3), e33078.
• Lehmann DJ, Schuur M, Warden DR, Hammond N, Belbin O, Kolsch H, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Morris CM, Barker R, Coto E, Alvarez V, Deloukas P, Mateo I, Gwilliam R, Combarros O, Arias-Vasquez A, Aulchenko YS, Ikram MA, Breteler MM, van Duijn CM, Oulhaj A, Heun R, Cortina-Borja M, Morgan K, Robson K, Smith AD. Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiology of Aging 2012, 33(1), 202.e1.
• Fitchett AE, Judge SJ, Morris CM. Using olive oil to orally dose laboratory rats. Animal Technology and Welfare 2012. In Press.
• Beenstock J, Sniehotta FF, White M, Bell R, Milne E, Araujo-Soares V. What helps and hinders midwives in engaging with pregnant women about stopping smoking? A cross-sectional survey of perceived implementation difficulties among midwives in the North East of England. Implementation Science 2012. In Press.