Newcastle University

Publications

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• Armstrong, J.L., Redfern, C.P.F., Veal, G.J. 13-cis Retinoic acid and isomerisation in paediatric oncology - Is changing shape the key to success?. Biochemical Pharmacology 2005, 69(9), 1299-1306.
• Sun Y, Wipat A, Pocock M, Lee PA, Watson P, Flanagan K, Worthington JT. A grid-based system for microbial genome comparison and analysis. In: IEEE International Symposium on Cluster Computing and the Grid, CCGrid 2005. 2005, Cardiff, Wales: IEEE.
• Blakely EL, Mitchell AL, Fisher N, Meunier B, Nijtmans LG, Schaefer AM, Jackson MJ, Turnbull DM, Taylor RW. A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast. FEBS Journal 2005, 272(14), 3583-3592.
• Lawless C, Semenov MA, Jamieson PD. A wheat canopy model linking leaf area and phenology. European Journal of Agronomy 2005, 22(1), 19-32.
• Chabanon H, Mickleburgh I, Burtle B, Pedder C, Hesketh J. An AU-rich stem-loop structure is a critical feature of the perinuclear localization signal of c-myc mRNA. Biochemical Journal 2005, 392(3), 475-483.
• Stojkovic P, Lako M, Stewart R, Przyborski S, Armstrong L, Evans J, Herbert M, Hyslop L, Ahmad S, Murdoch A, Strachan T, Stojkovic M. An Autogeneic Feeder Cell System That Efficiently Supports Growth of Undifferentiated Human Embryonic Stem Cells. Stem Cells 2005, 23(3), 306-314.
• Stojkovic P, Lako M, Stewart R, Przyborski S, Armstrong L, Evans J, Murdoch A, Strachan T, Stojkovic M. An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells. Stem Cells 2005, 23(3), 306-314.
• Nury D, Chabanon H, Levadoux-Martin M, Hesketh J. An eleven nucleotide section of the 3′- untranslated region is required for perinuclear localization of rat metallothionein-1 mRNA. Biochemical Journal 2005, 387(2), 419-428.
• Newton JL, Donaldson P, Parry S, Kenny RA, Smith J, Gibson AM, Morris C. Angiotensin converting enzyme insertion/deletion polymorphisms in vasovagal syncope. Europace 2005, 7(4), 396-399.
• Mickleburgh I, Burtle B, Hollas H, Campbell G, Chrzanowska-Lightowlers Z, Vedeler A, Hesketh J. Annexin A2 binds to the localization signal in the 3′ untranslated region of c-myc mRNA. FEBS Journal 2005, 272(2), 413-421.
• Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Caminci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang C, Hallinan J, Mattick J, Hume DA, Lipovitch L, Batalov S, Engstrom PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlstedt C. Antisense Transcription in the Mammalian Transcriptome. Science 2005, 309(5740), 1564-1566.
• Vollbach H, Heun R, Morris CM, Edwardson JA, McKeith IG, Jessen F, Schulz A, Maier W, Kolsch H. APOA1 polymorphism influences risk for early-onset nonfamiliar AD. Annals of Neurology 2005, 58(3), 436-441.
• Lawless C, Semenov MA. Assessing lead-time for predicting wheat growth using a crop simulation model. Agricultural and Forest Meteorology 2005, 135(1-4), 302-313.
• Nowotny P, Hinrichs AL, Smemo S, Kauwe JSK, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, Gibson AM, McKeith IG, Perry RH, Morris CM, Thal L, Morris JC, O'Donovan MC, Lovestone S, Grupe A, Hardy J, Owen MJ, Williams J, Goate A. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 2005, 136(1), 62-68.
• Kirkwood TBL. Asymmetry and the origins of ageing. Mechanisms of Ageing and Development 2005, 126(5), 533-534.
• Hindmarsh PN, Wood CE, Seal CJ, Adamson AJ, Mathers JC, Moynihan PJ. Attitudes and perceptions towards healthier eating of older adults residing in sheltered housing. In: Proceedings of the Nutrition Society. 2005, Dublin: Cambridge University Press.
• Shaw OJ, Steggles LJ, Wipat A. Automatic Parameterisation of Stochastic Petri Net Models of Biological Networks. Newcastle upon Tyne: School of Computing Science, University of Newcastle upon Tyne, 2005. School of Computing Science Technical Report Series 909.
• Winterthun S, Ferrari G, He L, Taylor RW, Zeviani M, Turnbull DM, Engelsen BA, Moen G, Bindoff LA. Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase γ mutations. Neurology 2005, 64(7), 1204-1208.
• Armstrong L, Saretzki G, Peters H, Wappler I, Evans J, Hole N, von Zglinicki T, Lako M. “Overexpression of Tert results in enhanced proliferation of murine ES cells, protection from oxidative stress and commitment to haematopoietic lineages”. Stem Cells 2005, 23(4), 516-529.
• Hawkes AG, Steel M, Sherlock C, Papaspiliopoulos O, Jacobsen M, Sorensen M, Boys RJ. Bayesian analysis of single-molecule experimental data - Discussion. Journal of the Royal Statistical Society Series C: Applied Statistics 2005, 54, 496-506.
• Golightly A, Wilkinson DJ. Bayesian inference for stochastic kinetic models using a diffusion approximation. Biometrics 2005, 61(3), 781-894.
• Aitkin M, Boys RJ, Chadwick TJ. Bayesian point null hypothesis testing via the posterior likelihood ratio. Statistics and Computing 2005, 15(3), 217-230.
• Aitkin M, Boys RJ, Chadwick T. Bayesian point null hypothesis testing via the posterior likelihood ratio. Statistics and Computing 2005, 15(3), 217-230.
• Maguire A, Zohouri FV, Mathers JC, Steen IN, Hindmarch PN, Moynihan PJ. Bioavailability of fluoride in drinking water: A human experimental study. Journal of Dental Research 2005, 84(11), 989-993.
• Williams AL, Kersey PJ, Pruess M, Apweiler R. Biological Databases: Infrastructure, Content, and Integration. In: Azuaje F; Dopazo J, ed. Data Analysis and Visualization in Genomics and Proteomics. Hoboken, New Jersey: John Wiley & Sons, 2005, pp.11-28.
• Lydall DA, Whitehall SK. Chromatin and the DNA damage response. DNA Repair 2005, 4(10), 1195-1207.
• Howell N, Kubacka I, Keers SM, Turnbull DM, Chinnery PF. Co-segregation and heteroplasmy of two coding-region mtDNA mutations within a matrilineal pedigree. Human Genetics 2005, 116(1-2), 28-32.
• Hill MH, Mathers JC, Williams EA, Spiers A, Duckworth Y, Welfare M, Powers HJ. Colon mucosal folate is responsive to folic acid supplements and correlates with plasma folate. In: Proceedings of the Nutrition Society. 2005, University of East Anglia, Norwich: Cambridge University Press.
• Kirkwood TBL. Commentary on "How is the evolutionary biological theory of aging holding up against attacks?. American Aging Association Newsletter 2005, (May), 14-15.
• Wilson KE, Marouga R, Prime JE, Pashby DP, Orange PR, Crosier S, Keith AB, Lathe R, Mullins J, Estibeiro P, Bergling H, Hawkins E, Morris CM. Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling. Proteomics 2005, 5(15), 3851-3858.
• Kirkwood TBL, Boys RJ, Gillespie CS, Proctor CJ, Shanley DP, Wilkinson DJ. Computer Modeling in the Study of Aging. In: Austad, S.N., Masoro, E.J, ed. Handbook of the Biology of Aging. Amsterdam; Boston: Academic Press, 2005, pp.334-359.
• Loughlin J. Crystals in hand. Arthritis Research & Therapy 2005, 7(5), 187-188.
• Barron MJ, Chinnery PF, Howel D, Blakely EL, Schaefer AM, Taylor RW, Turnbull DM. Cytochrome c oxidase deficient muscle fibres: Substantial variation in their proportions within skeletal muscles from patients with mitochondrial myopathy. Neuromuscular Disorders 2005, 15(11), 768-774.
• Stojkovic M, Stojkovic P, Leary C, Hall VJ, Armstrong L, Herbert M, Nesbitt M, Lako M, Murdoch A. Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes. Reproductive BioMedicine Online 2005, 11(2), 226-231.
• Jarvis S, Spiers A, Duckworth Y, Welfare M, Powers HJ, Mathers JC, Williams EA. Dietary characteristics of gastroenterology patients. In: Proceedings of the Nutrition Society. 2005, University of East Anglia, Norwich: Cambridge University Press.
• Hardcastle I, Cockcroft X, Curtin NJ, El-Murr M, Leahy JJJ, Stockley M, Golding BT, Rigoreau L, Richardson C, Smith G, Griffin RJ. Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach. Journal of Medicinal Chemistry 2005, 48(24), 7829-7846.
• Boys RJ, Henderson DA. Discussion of "A Bayesian approach to DNA sequence segmentation": Commentary. Biometrics 2005, 61(2), 637-639.
• Boys RJ. Discussion of "Bayesian analysis of single-molecule experimental data" by Kou, Xie and Liu. Royal Statistical Society. Journal. Series C: Applied Statistics 2005, 54(3), 503-504.
• Coxhead JM, Williams EA, Mathers JC. DNA mismatch repair status may influence anti-neoplastic effects of butyrate. In: Conference on Molecular Biology of Colorectal Cancer. 2005, Bristol, UK: Biochemical Society Transactions, Portland Press Ltd.
• Hyslop L, Stojkovic M, Armstrong L, Walter T, Stojkovic P, Przyborski S, Herbert M, Murdoch A, Strachan T, Lako M. Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages. Stem Cells 2005, 23(8), 1035-1043.
• Payne VA, Arden C, Wu C, Lange AJ, Agius L. Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes. Diabetes 2005, 54(7), 1949-1957.
• Coxhead JM, Bal W, Shenton BK, Williams EA, Mathers JC. Effect of butyrate on induction of aneuploidy in colorectal carcinoma cell lines. In: Proceedings of the Nutrition Society. 2005, University of East Anglia, Norwich: Cambridge University Press.
• Fishel M, Newell D, Griffin R, Davison R, Wang L, Curtin NJ, Zuhowski E, Kasza K, Egorin M, Moschel R, Dolan M. Effect of cell cycle inhibition on cisplatin-induced cytotoxicity. Journal of Pharmacology and Experimental Therapeutics 2005, 312(1), 206-213.
• Pagmantidis V, Bermano G, Villette S, Broom I, Arthur J, Hesketh J. Effects of Se-depletion on glutathione peroxidase and selenoprotein W gene expression in the colon. FEBS Letters 2005, 579(3), 792-796.
• Michailidis G, Saretzki G, Hall J. Endogenous and ectopic expression of telomere regulating genes in chicken embryonic fibroblasts. Biochemical and Biophysical Research Communications 2005, 335(1), 240-246.
• Forrest IA, Murphy DM, Lordan JL, Pritchard G, Jones D, Robertson H, Cawston TE, Dark JH, Kirby JA, Ward C, Corris PA. Epithelial to mesenchymal transition in clinically stable lung transplant recipients. In: Journal of Heart and Lung Transplantation: 25th Anniversary Meeting of the International Society for Heart and Lung Transplantation. 2005, Philadelphia, Pennsylvania, USA: Elsevier Inc.
• Hallinan J. Evolving neural networks for the classification of Malignancy Associated Changes. In: 6th International Conference Intelligent Data Engineering and Automated Learning (IDEAL). 2005, Brisbane, Australia: Springer.
• Basterfield L, Mathers JC. Exercise and bowel cancer: Wheel running versus treadmill running in Min mice. In: International Research Conference on Diet, Nutrition and Cancer. 2005, Washington, DC, USA: Journal of Nutrition: American Society for Nutrition.
• Sun Y, Wipat A, Pocock M, Lee P, Flanagan K, Worthington J. Exploring Microbial Genome Sequences to Identify Protein Families on the Grid. Newcastle upon Tyne: School of Computing Science, University of Newcastle upon Tyne, 2005. School of Computing Science Technical Report Series 931.
• Newton JL, Kerr S, Pairman J, McLaren A, Norton M, Kenny RA, Morris CM. Familial neurocardiogenic (vasovagal) syncope. American Journal of Medical Genetics: Part A 2005, 133(2), 176-179.
• Kirkwood T. Fantastic voyage: Live long enough to live forever. Nature 2005, 436(7053), 915-916.
• Corazzari, M., Lovat, P.E., Oliverio, S., Di Sano, F., Donnorso, R., Redfern, C.P.F., Piacentini, M. Fenretinide: A p53-independent way to kill cancer cells. Biochemical and Biophysical Research Communications 2005, 331(3), 810-815.
• Kirkwood TBL, Shanley DP. Food restriction, evolution and ageing. Mechanisms of Ageing and Development 2005, 126(9), 1011-1016.
• Hallinan J. Game of Life. In: Scott, A, ed. Encyclopedia of Nonlinear Science. New York; London: Routledge, 2005, pp.352-354.
• Hallinan J. Game Theory. In: Scott, A, ed. Encyclopedia of Nonlinear Science. New York; London: Routledge, 2005, pp.355-356.
• Lake AA, Mathers JC, Rugg-Gunn AJ, Adamson AJ. Gender and socio-demographic factors influencing dietary change from adolescence to adulthood: The ASH30 study. In: South African Journal of Clinical Nutrition. 2005, Health and Medical Publishing Group.
• Kawahara C, Forster T, Chapman K, Carr A, Loughlin J. Genetic association analysis of the IGFBP7, ADAMTS3, and IL8 genes as the potential osteoarthritis susceptibility that maps to chromosome 4q. Annals of the Rheumatic Diseases 2005, 64(3), 474-476.
• Spencer JM, Loughlin J, Clipsham K, Carr AJ. Genetic background increases the risk of hip osteoarthritis. Clinical Orthopaedics and Related Research 2005, (431), 134-137.
• Palmer CL, Lim W, Hastie PGR, Toward M, Korolchuk VI, Burbidge SA, Banting G, Collingridge GL, Isaac JTR, Henley JM. Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron 2005, 47(4), 487-494.
• Young DA, Lakey RL, Pennington CJ, Jones D, Kevorkian L, Edwards DR, Cawston TE, Clark IM. Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Research & Therapy 2005, 7(3), R503-R512.
• Cragg RA, Phillips SR, Piper JM, Varma JS, Campbell FC, Mathers JC, Ford D. Homeostatic regulation of zinc transporters in the human small intestine by dietary zinc supplementation. Gut 2005, 54(4), 469-478.
• von Zglinicki T, Saretzki G, Ladhoff J, di Fagagna FD, Jackson SP. Human cell senescence as a DNA damage response. In: Mechanisms of Ageing and Development: 2nd International Conference on Functional Genomics of Ageing. 2005, Hersonissos, Greece: Elsevier Ireland Ltd.
• Stojkovic P, Lako M, Armstrong L, Stojkovic M. Human embryonic stem cells express markers of pluripotency and differentiate under long-term in vitro growth conditions. Medicus 2005, 6(1), 6-10.
• Hyslop LA, Armstrong L, Stojkovic M, Lako M. Human embryonic stem cells: Biology and clinical implications. Expert Reviews in Molecular Medicine 2005, 7(19), 1-21.
• Stojkovic P, Lako M, Przyborski S, Stewart R, Armstrong L, Evans J, Zhang X, Stojkovic M. Human-serum matrix supports undifferentiated growth of human embryonic stem cells. Stem Cells 2005, 23(7), 895-902.
• Rowan E, Morris CM, Stephens S, Ballard C, Dickinson H, Rao H, Saxby BK, McLaren AT, Kalaria RN, Kenny RA. Impact of hypertension and apolipoprotein E4 on poststroke cognition in subjects >75 years of age. Stroke 2005, 36(9), 1864-1868.
• Basterfield L, Reul JMHM, Mathers JC. Impact of physical activity on intestinal cancer development in mice. In: International Research Conference on Diet, Nutrition and Cancer. 2005, Washington, DC: Journal of Nutrition, American Society for Nutrition.
• Emanueli C, Lako M, Stojkovic M, Madeddu P. In search of the best candidate for regeneration of ischemic tissues: are embryonic/fetal stem cells more advantageous than adult counterparts?. Thrombosis and Haemostasis 2005, 94(4), 738-749.
• Emanueli C, Lako M, Stojkovic M, Madeddu P. In search of the best candidate for regeneration of ischemic tissues: Are embryonic/fetal stem cells more advantageous than adult counterparts?. Thrombosis and Haemostasis 2005, 94(4), 738-749.
• Hampson LJ, Agius L. Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism. Diabetes 2005, 54(3), 617-623.
• Armstrong, J., Ruiz, M., Boddy, A. V., Redfern, C., Pearson, A. D. J., Veal, G. J. Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells. British Journal of Cancer 2005, 92(4), 696-704.
• Kobaek-Larsen M, Christensen LP, Vach W, Ritskes-Hoitinga J, Brandt K. Inhibitory effects of feeding with carrots or (-)-falcarinol on development of azoxymethane-induced preneoplastic lesions in the rat colon. Journal of Agricultural and Food Chemistry 2005, 53(5), 1823-1827.
• Thybo AK, Bechmann IE, Brandt K. Integration of sensory and objective measurements of tomato quality: Quantitative assessment of the effect of harvest date as compared with growth medium (soil versus rockwool), electrical conductivity, variety and maturity. Journal of the Science of Food and Agriculture 2005, 85(13), 2289-2296.
• Tyson J, Spiers A, Caple F, Hesketh JE, Mathers JC. Inter-individual variation in nucleotide excision repair capacity: potential scope for dietary modulation of DNA repair. In: Proceedings of the Nutrition Society. 2005, University of East Anglia, Norwich: Cambridge University Press.
• Mustafa Z, Dowling B, Chapman K, Sinsheimer JS, Carr A, Loughlin J. Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population. Arthritis & Rheumatism 2005, 52(11), 3502-3506.
• Hardcastle I, Ahmed S, Atkins H, Calvert AH, Curtin NJ, Farnie G, Golding BT, Griffin R, Guyenne S, Hutton C, Källblad P, Kemp S, Kitching M, Newell D, Norbedo S, Northen J, Reid R, Saravanan K, Willems H, Lunec J. Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction. Bioorganic and Medicinal Chemistry Letters 2005, 15(5), 1515-1520.
• Peake NJ, Khawaja K, Myers A, Jones D, Cawston TE, Rowan AD, Foster HE. Levels of matrix metalloproteinase (MMP)-1 in paired sera and synovial fluids of juvenile idiopathic arthritis patients: relationship to inflammatory activity, MMP-3 and tissue inhibitor of metalloproteinases-1 in a longitudinal study. Rheumatology 2005, 44(11), 1383-1389.
• Blakely EL, de Silva R, King A, Schwarzer V, Harrower T, Dawidek G, Turnbull DM, Taylor RW. LHON/MELAS overlap syndrome associated with a mitochondrial MTND1 gene mutation. European Journal of Human Genetics 2005, 13(5), 623-627.
• Craigie AM, Adamson AJ, Lake AA, Gibbons M, Wood C, Matthews JNS, Rugg-Gunn AJ, Mathers JC. Lifecourse influences on nutrient intake in adulthood. In: Proceedings of the Nutrition Society. 2005, University of East Anglia, Norwich: Cambridge University Press.
• Lake AA, Mathers JC, Rugg-Gunn AJ, Adamson AJ. Longitudinal dietary change from adolescence to adulthood: Explanatory factors for dietary change. In: Fourth Annual Conference of the International Society of Behavioural Nutrition and Physical Activity (ISBNPA). 2005, Amsterdam, The Netherlands: International Society of Behaviorial Nutrition and Physical Activity.
• Getliffe KM, Al Dulaimi D, Martin-Ruiz C, Holder RL, Von Zglinicki T, Morris A, Nwokolo CU. Lymphocyte telomere dynamics and telomerase activity in inflammatory bowel disease: Effect of drugs and smoking. Alimentary Pharmacology and Therapeutics 2005, 21(2), 121-131.
• Homer HA, McDougall A, Levasseur M, Murdoch AP, Herbert M. Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes. Reproduction 2005, 130(6), 829-843.
• Homer HA, McDougall A, Levasseur M, Yallop K, Murdoch AP, Herbert M. Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes. Genes and Development 2005, 19(2), 202-207.
• Brown, A.M., Riddoch, F.C, Robson, A., Redfern, C.P.F., Cheek, T.R. Mechanistic and functional changes in Ca2+ entry after retinoic acid-induced differentiation of neuroblastoma cells. Biochemical Journal 2005, 388(3), 941-948.
• Belshaw NJ, Elliott GO, Williams EA, Mathers JC, Buckley L, Bahari B, Johnson IT. Methylation of the ESR1 CpG island in the colorectal mucosa is an 'all or nothing' process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse. In: The Molecular Biology of Colorectal Cancer. 2005, Bristol, UK: Biochemical Society Transactions: Portland Press Ltd.
• Andrews H, White K, Thomson C, Edgar J, Bates D, Griffiths I, Turnbull D, Nichols P. Mitochondria and axonal loss in multiple sclerosis: the shiverer mouse as a model of secondary progressive MS. In: 15th Meeting of the European-Neurological-Society. 2005, Vienna, Austria: Springer.
• Walker M, Taylor RW, Turnbull DM. Mitochondrial diabetes. Diabetic Medicine 2005, 22(4), 18-20.
• Baudouin S, Saunders D, Tiangyou W, Elson J, Poynter J, Pyle A, Keers S, Turnbull D, Howell N, Chinnery P. Mitochondrial DNA and survival after sepsis: A prospective study. Lancet 2005, 366(9503), 2118-2121.
• Taylor RW, Turnbull DM. Mitochondrial DNA mutations in human disease. Nature Reviews Genetics 2005, 6(5), 389-402.
• Andrews HE, Nichols PP, Bates D, Turnbull DM. Mitochondrial dysfunction plays a key role in progressive axonal loss in Multiple Sclerosis. Medical Hypotheses 2005, 64(4), 669-677.
• Proctor CJ, Soti C, Boys RJ, Gillespie CS, Shanley DP, Wilkinson DJ, Kirkwood TBL. Modelling the actions of chaperones and their role in ageing. Mechanisms of Ageing and Development 2005, 126(1), 119-131.
• Drenos F, Kirkwood TBL. Modelling the disposable soma theory of ageing. In: Mechanisms of Ageing and Development: 2nd International Conference on Functional Genomics of Ageing. 2005, Hersonissos, Greece: Elsevier Ireland Ltd.
• Milne EMG. Mortality spike at New Year but not Christmas in North East England. European Journal of Epidemiology 2005, 20(10), 849-854.
• Howell N, Elson JL, Chinnery PF, Turnbull DM. mtDNA mutations and common neurodegenerative disorders. Trends in Genetics 2005, 21(11), 583-586.
• Hallinan JS, Jackway PT. Network motifs, feedback loops and the dynamics of genetic regulatory networks. In: IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB). 2005, San Diego, California, USA: IEEE.
• Stewart R, Lako M, Horrocks GM, Przyborski SA. Neural development by transplanted human embryonal carcinoma stem cells expressing green fluorescent protein. Cell Transplantation 2005, 14(6), 339-351.
• Milne E. NHS smoking cessation services and smoking prevalence: observational study. British Medical Journal 2005, 330(7494), 760-760.
• Jacobs HT, Turnbull DM. Nuclear genes and mitochondrial translation: A new class of genetic disease. Trends in Genetics 2005, 21(6), 312-314.
• Mathers JC. Nutrition and epigenetics - How the genome learns from experience. Nutrition Bulletin 2005, 30(1), 6-12.
• Richardson C, Smith T, Schaefer A, Turnbull D, Griffiths P. Ocular motility findings in chronic progressive external ophthalmoplegia. Eye 2005, 19(3), 258-263.
• Hui W, Barksby HE, Young DA, Cawston TE, McKie N, Rowan AD. Oncostatin M in combination with tumour necrosis factor alpha induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or-2. Annals of the Rheumatic Diseases 2005, 64(11), 1624-1632.
• Young DA, Lakey RL, Pennington CJ, Jones D, Kevorkian L, Edwards DR, Cawston TE, Clark IM. Oncostatin M in combination with tumour necrosis factor alpha induces a chondrocyte membrane-associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2. Arthritis Research & Therapy 2005, 7(3), R503-512.
• Schaefer AM, Blakely EL, Griffiths PG, Turnbull DM, Taylor RW. Ophthalmoplegia due to mitochondrial DNA disease: The need for genetic diagnosis. Muscle and Nerve 2005, 32(1), 104-107.
• Armstrong L, Saretzki G, Peters H, Wappler I, Evans J, Hole N, Von Zglinicki T, Lako M. Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage. Stem Cells 2005, 23(4), 516-529.
• Myatt, S., Redfern, C.P.F., Burchill, S. p38MAPK-dependent sensitivity of Ewing's sarcoma family of tumors to fenretinide-induced cell death. Clinical Cancer Research 2005, 11(8), 3136-3148.
• Foster E, Matthews JNS, Mathers JC, Moynihan PJ, Adamson AJ. Packaged food intake by children aged 0 to 16 years (g/kg body weight). In: Proceedings of the Nutrition Society. 2005, University of East Anglia, Norwich: Cambridge University Press.
• Wilkinson DJ. Parallel Bayesian Computation. In: Kontoghiorghes, E.J, ed. Handbook of Parallel Computing and Statistics. Boca Raton, Florida; London, UK: Marcel Dekker/CRC Press, 2005, pp.481-512.
• Curtin NJ. PARP inhibitors for cancer therapy. Expert Reviews in Molecular Medicine 2005, 7(4), 1-20.
• Curtin NJ. PARP inhibitors for cancer therapy. Expert Reviews in Molecular Medicine 2005, 7(4), 1-20.
• Qatatsheh A, Seal CJ, Welfare MR, Hesketh JE. Patients with ulcerative colitis show an altered frequency distribution of a single novel polymorphism (SNP) in the gene encoding the phospholipid hydroperoxide glutathione peroxidase 4 (GPX4). In: Proceedings of the Nutrition Society. 2005, Telford International Centre, Telford, UK: Cambridge University Press.
• Hyland RM, Hill M, Adamson AJ, Seal C, Mathers JC, Moynihan PJ. Perceptions of peer educators on their training and delivery of a dietary intervention to older adults. Journal of Human Nutrition and Dietetics 2005, 18(6), 475.
• Kirkwood T. Perspectives from Evolutionary Biology. In: Stock, G., Lessl, M., Baltes, P, ed. The Future of Aging: Individual and Societal Implications. Berlin: Ernst Schering Research Foundation, 2005. In Press.
• Willits, I., Price, L., Parry, A. P., Tilby, M. J., Ford, D., Cholerton, S., Pearson, A. D. J., Boddy, A. V. Pharmacokinetics and metabolism of ifosfamide in relation to DNA damage assessed by the COMET assay in children with cancer. British Journal of Cancer 2005, 92(9), 1626-1635.
• Gautrey H, McConnell J, Hall J, Hesketh J. Polarised distribution of the RNA-binding protein Staufen in differentiated intestinal epithelial cells. FEBS Letters 2005, 579(10), 2226-2230.
• Loughlin J. Polymorphism in signal transduction is a major route through which osteoarthritis susceptibility is acting. Current Opinion in Rheumatology 2005, 17(5), 629-633.
• Ells LJ, Seal CJ, Kettlitz B, Bal W, Mathers JC. Postprandial glycaemic, lipaemic and haemostatic responses in ingestion of rapidly and slowly digested starches in healthy young women. British Journal of Nutrition 2005, 94(6), 948-955.
• Pennati M, Campbell AJ, Curto M, Binda M, Cheng Y, Wang L, Curtin NJ, Golding BT, Griffin RJ, Hardcastle IR, Henderson A, Zaffaroni N, Newell DR. Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: A possible role for survivin down-regulation. Molecular Cancer Therapeutics 2005, 4(9), 1328-1337.
• Maringele L, Lydall D. Pulsed Field Gel Electrophoresis of Budding Yeast Chromosomes. In: Xiao, W, ed. Yeast Protocols. Totawa, New Jersey: Humana Press, 2005, pp.65-74.
• Peach CA, Carr AJ, Loughlin J. Recent advances in the genetic investigation of osteoarthritis. Trends in Molecular Medicine 2005, 11(4), 186-191.
• Korolchuk VI, Cozier G, Banting G. Regulation of CK2 activity by phosphatidylinositol phosphates. Journal of Biological Chemistry 2005, 280(49), 40796-40801.
• Boys RJ, Henderson DA. Rejoinder to "Discussion of "A Bayesian approach to DNA segmentation by R. J. Boys and D. A. Henderson" by Booth, Burden, Maindonald, Santoso, Wakefield and Wilson". Biometrics 2005, 61(2), 635-639.
• Riddoch, F.C., Rowbotham, S.E., Brown, A.M., Redfern, C.P.F., Cheek, T.R. Release and sequestration of Ca2+ by a caffeine- and ryanodine-sensitive store in a sub-population of human SH-SY5Y neuroblastoma cells. Cell Calcium 2005, 38(2), 111-120.
• Nelson DE, Horton CA, See V, Johnson JR, Nelson G, Spiller DG, Kell DB, White MRH. Response to Comment on "Oscillations in NF-kappa B signaling control the dynamics of gene expression". Science 2005, 308(5718), 52.
• Homer HA, McDougall A, Levasseur M, Herbert M. Restaging the spindle assembly checkpoint in female mammalian meiosis I. Cell Cycle 2005, 4(5), 650-653.
• Mathers JC. Reversal of DNA hypomethylation by folic acid supplements: Possible role in colorectal cancer prevention. Gut 2005, 54(5), 579-581.
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