Newcastle University

Publications

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• Murr M, Cano C, Golding BT, Hardcastle IR, Hummersome M, Frigerio M, Curtin NJ, Menear K, Richardson C, Smith G, Griffin R. 8-Biarylchromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK). Bioorganic and Medicinal Chemistry Letters 2008, 18(17), 4885-4890.
• Stewart JD, Hudson G, Yu Wai Man P, Blakeley EL, He L, Horvath R, Maddison P, Wright A, Griffiths PG, Turnbull DM, Taylor RW, Chinnery PF. OPA1 in multiple mitochondrial DNA deletion disorders. Neurology 2008, 71(22), 1829-1831.
• Greenall A, Lei GY, Swan DC, James K, Wang LM, Peters H, Wipat A, Wilkinson DJ, Lydall D. A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD(+) biosynthetic gene BNA2 in chromosome end protection. Genome Biology 2008, 9(10), R146.
• Addinall SG, Downey M, Yu M, Zubko MK, Dewar J, Leake A, Hallinan J, Shaw O, James K, Wilkinson DJ, Wipat A, Durocher D, Lydall DA. A Genome-wide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 2008, 180(4), 2251-2266.
• Swalwell H, Blakely E, Sutton R, Tonska K, Elstner M, He L, Taivassalo T, Burns D, Turnbull DM, Haller R, Davidson M, Taylor RW. A homoplasmic mtDNA variant can influence the phenotype of the pathogenic m.7472Cins MTTS1 mutation: Are two mutations better than one?. European Journal of Human Genetics 2008, 16(10), 1265-1274.
• Yang C, Przyborski S, Cooke MJ, Zhang X, Stewart R, Anyfantis G, Atkinson SP, Saretzki GC, Armstrong L, Lako M. A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation. Stem Cells 2008, 26(4), 850-863.
• Chapman K, Takahashi A, Meulenbelt I, Watson C, Rodriguez-Lopez J, Egli R, Tsezou A, Malizos KN, Kloppenburg M, Shi D, Southam L, Breggen Rvander, Donn R, Qin J, Doherty M, Slagboom PE, Wallis G, Kamatani N, Jiang Q, Gonzalez A, Loughlin J, Ikegawa S. A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Human Molecular Genetics 2008, 17(10), 1497-504.
• Ahmad S, Kolli S, Li DQ, de Paiva CS, Pryzborski S, Dimmick I, Armstrong L, Figueiredo FC, Lako M. A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells. Stem Cells 2008, 26(6), 1609-1619.
• Arasaradnam RP, Commane DM, Bradburn D, Mathers JC. A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 2008, 3(4), 193-198.
• Sampieri CL, Nuttall RK, Young DA, Goldspink D, Clark IM, Edwards DR. Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes. Matrix Biology 2008, 27(2), 128-138.
• Maimets T, Neganova I, Armstrong L, Lako M. Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells. Oncogene 2008, 27(40), 5277-5287.
• Reeve AK, Krishnan KJ, Turnbull DM. Age related mitochondrial degenerative disorders in humans. Biotechnology Journal 2008, 3(6), 750-756.
• Cree L, Patel S, Pyle A, Lynn S, Turnbull DM, Chinnery PF, Walker M. Age-related decline in mitochondrial DNA copy number in isolated human pancreatic islets. Diabetologia 2008, 51(8), 1440-1443.
• Parker SM, Goriwiec MR, Borthwick LA, Johnson G, Ward C, Lordan JL, Corris PA, Saretzki GC, Fisher AJ. Airway epithelial cell senescence in the lung allograft. American Journal of Transplantation 2008, 8(7), 1544-1549.
• Murphy DM, Forrest IA, Corris PA, Johnson GE, Small T, Jones D, Fisher AJ, Egan JJ, Cawston TE, Lordan JL, Ward C. Azithromycin attenuates effects of lipopolysaccharide on lung allograft bronchial epithelial cells. The Journal of Heart and Lung Transplantation 2008, 27(11), 1210-6.
• Boys RJ, Wilkinson DJ, Kirkwood TBL. Bayesian inference for a discretely observed stochastic kinetic model. Statistics and Computing 2008, 18(2), 125-135.
• Golightly A, Wilkinson D. Bayesian inference for nonlinear multivariate diffusion models observed with error. Computational Statistics and Data Analysis 2008, 52(3), 1674-1693.
• Loughlin J, Chapman K. Big is beautiful. Osteoarthritis Cartilage 2008, 16(3), 277-278.
• Bergmann MM, Gorman U, Mathers JC. Bioethical considerations for human nutrigenomics. Annual Review of Nutrition 2008, 28(1), 447-467.
• Mckay JA, Adriaens ME, Ford D, Relton CL, Evelo CTA, Mathers JC. Bioinformatic interrogation of expression array data to identify nutritionally regulated genes potentially modulated by DNA methylation. Genes & Nutrition 2008, 3(3-4), 167-171.
• Spencer JPE, Abd El Mohsen MM, Minihane A-M, Mathers JC. Biomarkers of the intake of dietary polyphenols: Strengths, limitations and application in nutrition research. British Journal of Nutrition 2008, 99(1), 12-22.
• Brandt K. Challenges in the control of food quality and safety. Outlooks on Pest Management 2008, 19(1), 34-38.
• Morin I, Ngo H-P, Greenall A, Zubko MK, Morrice N, Lydall D. Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. EMBO Journal 2008, 27(18), 2400-2410.
• Foster E, Matthews JNS, Lloyd J, Marshall L, Mathers JC, Nelson M, Barton KL, Wrieden WL, Cornelissen P, Harris J, Adamson AJ. Children's estimates of food portion size: The development and evaluation of three portion size assessment tools for use with children. British Journal of Nutrition 2008, 99(1), 175-184.
• Foster E, O'Keeffe M, Matthews JNS, Mathers JC, Nelson M, Barton KL, Wrieden WL, Adamson AJ. Children's estimates of food portion size: The effect of timing of dietary interview on the accuracy of children's portion size estimates. British Journal of Nutrition 2008, 99(1), 185-190.
• Murphy R, Turnbull DM, Walker M, Hattersley AT. Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation. Diabetic Medicine 2008, 25(4), 383-399.
• Zhang Q, Hui W, Litherland GJ, Barter MJ, Davidson R, Darrah C, Donell ST, Clark IM, Cawston TE, Robinson JH, Rowan AD, Young DA. Differential Toll-like receptor-dependent collagenase expression in chondrocytes. Annals of the Rheumatic Diseases 2008, 67(11), 1633-41.
• Tourniaire F, Minihane AM, Hesketh J, Lietz G. Do single nucleotide polymorphisms in beta-carotene dioxygenase-2 ( BCDO2) gene affect the postprandial response?. Proceedings of the Nutrition Society 2008, 67(OCE), E187.
• Fairweather-Tait SJ, Harvey LJ, Ford D. Does ageing affect zinc homeostasis and dietary requirements?. Experimental Gerontology 2008, 43(5), 382-388.
• Brown AE, Elstner M, Yeaman SJ, Turnbull DM, Walker M. Does impaired mitochondrial function affect insulin signaling and action in cultured human skeletal muscle cells?. American Journal of Physiology - Endocrinology and Metabolism 2008, 294(1), E97-E102.
• Bender A, Schwarzkopf RM, McMillan A, Krishnan KJ, Rieder G, Neumann M, Elstner M, Turnbull DM, Klopstock T. Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions. Journal of Neurology 2008, 255(8), 1231-1235.
• Saretzki G, Walter T, Atkinson S, Passos JF, Bareth B, Keith WN, Stewart R, Hoare S, Stojkovic M, Armstrong L, Von Zglinicki T, Lako M. Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells. Stem Cells 2008, 26(2), 455-464.
• Craddock T, Harwood CR, Hallinan J, Wipat A. e-Science: relieving bottlenecks in large-scale genome analyses. Nature Reviews in Microbiology 2008, 6(12), 948-954.
• Burn J, Bishop DT, Mecklin JP, Macrae F, Moslein G, Olschwang S, Bisgaard ML, Ramesar R, Eccles D, Maher ER, Bertario L, Jarvinen HJ, Lindblom A, Evans DG, Lubinski J, Morrison PJ, Ho JWC, Vasen HFA, Side L, Thomas HJW, Scott RJ, Dunlop M, Barker G, Elliott F, Jass JR, Fodde R, Lynch HT, Mathers JC, CAPP2 Investigators. Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome. New England Journal of Medicine 2008, 359(24), 2567-2578.
• Kristensen M, Ostergaard LF, Halekoh U, Jorgensen H, Lauridsen C, Brandt K, Bugel S. Effect of plant cultivation methods on content of major and trace elements in foodstuffs and retention in rats. Journal of the Science of Food and Agriculture 2008, 88(12), 2161-2172.
• Caslake MJ, Miles EA, Kofler BM, Lietz G, Curtis P, Armah CK, Kimber AC, Grew JP, Farrell L, Stannard J, Napper FL, Sala-Vila A, West AL, Mathers JC, Packard C, Williams CM, Calder PC, Minihane AM. Effect of sex and genotype on cardiovascular biomarker response to fish oils: The FINGEN Study. American Journal of Clinical Nutrition 2008, 88(3), 618-629.
• Ledran MH, Krassowska A, Armstrong L, Dimmick I, Renstrom J, Lang R, Yung S, Santibanez-Coref M, Dzierzak E, Stojkovic M, Oostendorp RAJ, Forrester L, Lako M. Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell Stem Cell 2008, 3(1), 85-98.
• Hapangama DK, Turner MA, Drury JA, Martin-Ruiz C, von Zglinicki T, Farquharson RG, Quenby S. Endometrial telomerase shows specific expression patterns in different types of reproductive failure. Reproductive BioMedicine Online 2008, 17(3), 416-424.
• Hapangama DK, Turner MA, Drury JA, Quenby S, Saretzki G, Martin-Ruiz C, Von Zglinicki T. Endometriosis is associated with aberrant endometrial expression of telomerase and increased telomere length. Human Reproduction 2008, 23(7), 1511-1519.
• Mathers JC, Belshaw NJ, Johnson IT. Epigenetic Determinants of Bowel Cancer Risk - Does Diet Matter?. In: 3rd Asia Pacific Nutrigenomics Conference. 2008, Melbourne, Australia: Journal of Nutrigenetics and Nutrigenomics: Karger.
• Atkinson SP, Koch CM, Clelland GK, Willcox S, Fowler JC, Stewart R, Lako M, Dunham I, Armstrong L. Epigenetic marking prepares the human HOXA cluster for the activation during differentiation of pluripotent cells. Stem Cells 2008, 26(5), 1174-1185.
• Mathers JC. Epigenomics: a basis for understanding individual differences?. In: Symposium on The Challenge of Translating Nutrition Research into Public Health Nutrition. 2008, Dublin: Proceedings of the Nutrition Society: Cambridge University Press.
• Proctor CJ, Gray DA. Explaining oscillations and variability in the p53-Mdm2 system. BMC Systems Biology 2008, 2, 1-20.
• Meplan C, Crosley LK, Nicol F, Horgan GW, Mathers JC, Arthur JR, Hesketh JE. Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: Interaction with sex. American Journal of Clinical Nutrition 2008, 87(4), 1019-1027.
• Neganova I, Lako M. G1 to S phase cell cycle transition in somatic and embryonic stem cells. Journal of Anatomy 2008, 213(1), 30-44.
• McKay JA, Williams EA, Mathers JC. Gender-specific modulation of tumorigenesis by folic acid supply in the Apc+/Min mouse during early neonatal life. British Journal of Nutrition 2008, 99(3), 550-558.
• Ryder JJ, Garrison K, Song F, Hooper L, Skinner J, Loke Y, Loughlin J, Higgins JP, MacGregor AJ. Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review. Annals of the Rheumatic Diseases 2008, 67(5), 584-91.
• Rodriguez-Lopez J, Mustafa Z, Pombo-Suarez M, Malizos KN, Rego I, Blanco FJ, Tsezou A, Loughlin J, Gomez-Reino JJ, Gonzalez A. Genetic variation including nonsynonymous polymorphisms of a major aggrecanase, ADAMTS-5, in susceptibility to osteoarthritis. Arthritis & Rheumatism 2008, 58(2), 435-441.
• Valdes AM, Loughlin J, Timms KM, van Meurs JJB, Southam L, Wilson SG, Doherty S, Lories RJ, Luyten FP, Gutin A, Abkevich V, Ge D, Hofman A, Uitterlinden AG, Hart DJ, Zhang F, Zhai G, Egli RJ, Doherty M, Lanchbury J, Spector TD. Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis. American Journal of Human Genetics 2008, 82(6), 1231-1240.
• Pritchett LE, Atherton KM, Mutch E, Ford D. Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line. Journal of Nutritional Biochemistry 2008, 19(11), 739-745.
• Gibson F, Anderson L, Babnigg G, Baker M, Berth M, Binz P-A, Borthwick A, Cash P, Day BW, Friedman DB, Garland D, Gutstein HB, Hoogland C, Jones NA, Khan A, Klose J, Lamond AI, Lemkin PF, Lilley KS, Minden J, Morris NJ, Paton NW, Pisano MR, Prime JE, Rabilloud T, Stead DA, Taylor CF, Voshol H, Wipat A, Jones AR. Guidelines for reporting the use of gel electrophoresis in proteomics. Nature Biotechnology 2008, 26(8), 863-864.
• Lazzaro F, Sapountzi V, Granata M, Pellicioli A, Vaze M, Haber JE, Plevani P, Lydall D, Muzi-Falconi M. Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. EMBO Journal 2008, 27(10), 1502-1512.
• Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, Rose C, Krishna G, Davies JE, Ttofi E, Underwood BR, Rubinsztein DC. Huntington's disease: from pathology and genetics to potential therapies. Biochemical Journal 2008, 412, 191-209.
• Kennelly MM, Baker MR, Birchall D, Hanley JP, Turnbull DM, Loughney AD. Hyperemesis gravidarum and first trimester sagittal sinus thrombosis. Journal of Obstetrics and Gynaecology 2008, 28(4), 453-454.
• Meulenbelt I, Min JL, Bos S, Riyazi N, Houwing-Duistermaat JJ, van der Wijk HJ, Kroon HM, Nakajima M, Ikegawa S, Uitterlinden AG, van Meurs JB, van der Deure WM , Visser TJ, Seymour AB, Lakenberg N, van der Breggen R , Kremer D, van Duijn CM, Kloppenburg M, Loughlin J, Slagboom PE. Identification of DIO2 as new susceptibility locus for symptomatic Osteoarthritis. Human Molecular Genetics 2008, 17(12), 1867-1875.
• Overbeck S, Uciechowski P, Ackland ML, Ford D, Rink L. Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9. Journal of Leukocyte Biology 2008, 83(2), 368-380.
• Ban M, Elson J, Walton A, Turnbull D, Compston A, Chinnery P, Sawcer S. Investigation of the role of mitochondrial DNA in multiple sclerosis susceptibility. PLoS One 2008, 3(8), e2891.
• Tilgner K, Atkinson SP, Golebiewska A, Stojkovic M, Lako M, Armstrong L. Isolation of Primordial Germ Cells from Differentiating Human Embryonic Stem Cells. Stem Cells 2008, 26(12), 3075-3085.
• Kolli S, Lako M, Figueiredo FC, Mudhar H, Ahmad S. Loss of corneal epithelial stem cell properties in outgrowths from human limbal explants cultured on intact amniotic membrane. Regenerative Medicine 2008, 3(3), 329-342.
• McDonald SAC, Greaves LC, Gutierrez-Gonzalez L, Rodriguez-Justo M, Deheragoda M, Leedham SJ, Taylor RW, Lee CY, Preston SL, Lovell M, Hunt T, Elia G, Oukrif D, Harrison R, Novelli MR, Mitchell I, Stoker DL, Turnbull DM, Jankowski JAZ, Wright NA. Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells. Gastroenterology 2008, 134(2), 500-510.
• Jackson KA, Valentine RA, Coneyworth LJ, Mathers JC, Ford D. Mechanisms of mammalian zinc-regulated gene expression. Biochemical Society Transactions 2008, 36(6), 1262-1266.
• Field D, Glöckner F, Garrity G, Gray T, Sterk P, Cochrane G, Vaughan R, Kolker E, Kottmann R, Kyrpides N, Angiuoli S, Dawyndt P, Guralnick R, Goldstein P, Hall N, Hirschman L, Kravitz S, Lister AL, Markowitz V, Thomson N, Whetzel T. Meeting report: The fourth Genomic Standards Consortium (GSC) workshop. In: The Fourth Genomic Standards Consortium (GSC) Workshop. 2008, National Institute for Environmental eScience (NIEeS), Cambridge: Mary Ann Liebert, Inc. Publishers.
• Mahad DJ, Ziabreva I, Lassmann H, Turnbull DM. Mitochondrial defects in acute multiple sclerosis lesions. Brain 2008, 131(7), 1722-1735.
• Reeve AK, Krishnan KJ, Turnbull D. Mitochondrial DNA mutations in desease, aging and neurodegeneration. Annals of the New York Academy of Sciences 2008, 1147, 21-29.
• Miwa S, Lawless C, von Zglinicki T. Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model. Aging Cell 2008, 7(6), 920-923.
• Pellicane G, Smith GR, Sarkisov L. Molecular Dynamics Characterization of Protein Crystal Contacts in Aqueous Solutions. Physical Review Letters 2008, 101(24), 248102.
• Hudson G, Amati-Bonneau P, Blakely E, Stewart J, He L, Schaefer A, Griffiths P, Ahlqvist K, Suomalainen A, Reynier P, McFarland R, Turnbull D, Chinnery P, Taylor R. Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: A novel disorder of mtDNA maintenance. Brain 2008, 131(2), 329-337.
• Reeve AK, Krishnan KJ, Elson JL, Morris CM, Bender A, Lightowlers RN, Turnbull DM. Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons. American Journal of Human Genetics 2008, 82(1), 228-235.
• Hallinan JS, Wipat A. Network Motifs in Context: An Exploration of the Evolution of Oscillatory Dynamics in Transcriptional Networks. In: IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology. 2008, Idaho, USA: IEEE.
• Gorelik J, Ali NN, Kadir SHSA, Lab M, Stojkovic P, Armstrong L, Sviderskaya EV, Negulyaev YA, Klenerman D, Bennett DC, Lako M, Harding SE, Stojkovic M, Korchev YE. Non-invasive Imaging of Stem Cells by Scanning Ion Conductance Microscopy: Future Perspective. Tissue Engineering Part C: Methods 2008, 14(4), 311-318.
• Fresquet M, Jackson GC, Loughlin J, Briggs MD. Novel mutations in exon 2 of MATN3 affect residues within the alpha-helices of the A-domain and can result in the intracellular retention of mutant matrilin-3. Human Mutation 2008, 29(2), 330.
• Blakely E, He L, Gardner JL, Hudson G, Walter J, Hughes I, Turnbull DM, Taylor RW. Novel mutations in the TK2 gene associated with fatal mitochondrial DNA depletion myopathy. Neuromuscular Disorders 2008, 18(7), 557-560.
• Stewart JD, Tennant S, Powell H, Pyle A, Blakeley EL, He L, Hudson G, Roberts M, du Plessis D, Gow D, Mewasingh LD, Hanna MG, Omer S, Morris AAM, Roxburgh R, Livingston J, McFarland R, Turnbull DM, Chinnery PF, Taylor RW. Novel POLG1 mutations associated with neuromuscular and liver phenotypes in adults and children. Journal of Medical Genetics 2008, 46(3), 209-214.
• Hesketh J. Nutrigenomics and selenium: Gene expression patterns, physiological targets, and genetics. Annual Review of Nutrition 2008, 28(1), 157-177.
• Ashwell M, Stone E, Mathers J, Barnes S, Compston J, Francis RM, Key T, Cashman KD, Cooper C, Khaw KT, Lanham-New S, Macdonald H, Prentice A, Shearer M, Stephen A. Nutrition and bone health projects funded by the UK Food Standards Agency: Have they helped to inform public health policy?. British Journal of Nutrition 2008, 99(1), 198-205.
• Rorbach J, Yusoff A, Tuppen H, Abg-Kamaludin D, Chrzanowska-Lightowlers Z, Taylor R, Turnbull D, Mcfarland R, Lightowlers R. Overexpression of human mitochondrial valyl tRNA synthetase can partially restore levels of cognate mt-tRNAVal carrying the pathogenic C25U mutation. Nucleic Acids Research 2008, 36(9), 3065-3074.
• Plummer ER, Jones C, Middleton M, Wilson R, Evans J, Olsen A, Curtin NJ, Boddy AV, McHugh P, Newell DR, Harris A, Johnson P, Steinfeldt H, Dewji R, Wang D, Robson L, Calvert AH. Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors. Clinical Cancer Research 2008, 14(23), 7917-7923.
• Sapountzi V, Logan IR, Nelson G, Cook S, Robson CN. Phosphorylation of Tat-interactive protein 60 kDa by protein kinase Cε is important for its subcellular localisation. International Journal of Biochemistry & Cell Biology 2008, 40(2), 236-244.
• Brandt K. Plant health, soil fertility relationships and food quality. In: Organic Agriculture in Asia. 2008, Dankook University, Korea: International Society of Organic Agriculture Research.
• Schaefer AM, McFarland R, Blakely EL, He L, Whittaker RG, Taylor RW, Chinnery PF, Turnbull DM. Prevalence of mitochondrial DNA disease in adults. Annals of Neurology 2008, 63(1), 35-39.
• Belshaw NJ, Elliott GO, Foxall RJ, Dainty JR, Pal N, Coupe A, Garg D, Bradburn DM, Mathers JC, Johnson IT. Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa. British Journal of Cancer 2008, 99(1), 136-142.
• Lawless C, Semenov MA, Jamieson PD. Quantifying the effect of uncertainty in soil moisture characteristics on plant growth using a crop simulation model. Field Crops Research 2008, 106(2), 138-147.
• Lauridsen C, Yong C, Halekoh U, Bugel SH, Brandt K, Christensen LP, Jorgensen H. Rats show differences in some biomarkers of health when eating diets based on ingredients produced with three different cultivation strategies. Journal of the Science of Food and Agriculture 2008, 88(4), 720-732.
• Murphy JL, Blakely EL, Schaefer AM, He L, Wyrick P, Haller RG, Taylor RW, Turnbull DM, Taivassalo T. Resistance training in patients with single, large-scale deletions of mitochondrial DNA. Brain 2008, 131(11), 2832-2840.
• Burn J, Bishop DT, Mecklin J, Macrae F, Moslein G, Olschwang S, Bisgaard M, Ramesar R, Elliott F, Mathers J. Results of the CAPP-2-trial (Aspirin and resistant starch) in HNPCC gene carriers. In: EJC Supplements: 5th International Conference on Cancer Prevention. 2008, St Gallen, Switzerland: Pergamon.
• Mahad DJ, Lassmann H, Turnbull DM. Review: Mitochondria and disease progression in multiple sclerosis. Neuropathology and Applied Neurobiology 2008, 34(6), 577-589.
• Dronamraju SS, Coxhead JM, Kelly SB, Mathers JC. Role of DNA-mismatch repair in anti-neoplastic effects of butyrate. Proceedings of the Nutrition Society 2008, 67(OCE2), E87.
• Mathers JC. Session 2: Personalised nutrition Epigenomics: A basis for understanding individual differences?. Proceedings of the Nutrition Society 2008, 67(4), 390-394.
• Stewart R, Yang C, Anyfantis G, Przyborski S, Hole N, Strachan T, Stojkovic M, Keith WN, Armstrong L, Lako M. Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells. Regenerative Medicine 2008, 3(4), 505-522.
• Murphy DM, Forrest IA, Corris PA, Johnson GE, Small T, Jones D, Fisher AJ, Egan JJ, Cawston TE, Ward C, Lordan JL. Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients. American Journal of Physiology: Lung Cellular and Molecular Physiology 2008, 294(3), L592-L599.
• Bradbury J, Mulvaney CE, Adamson AJ, Seal CJ, Mathers JC, Moynihan PJ. Sources of total, non-milk extrinsic, and intrinsic and milk sugars in the diets of older adults living in sheltered accommodation. British Journal of Nutrition 2008, 99(3), 649-652.
• Tsolou A, Passos JF, Nelson G, Arai Y, von Zglinicki T. ssDNA fragments induce cell senescence by telomere uncapping. Experimental Gerontology 2008, 43(10), 892-899.
• Gautrey H, McConnell J, Lako M, Hall J, Hesketh J. Staufen1 is expressed in preimplantation mouse embryos and is required for embryonic stem cell differentiation. Biochimica et Biophysica Acta: Molecular Cell Research 2008, 1783(10), 1935-1942.
• Pagmantidis V, Meplan C, Van Schothorst EM, Keijer J, Hesketh JE. Supplementation of healthy volunteers with nutritionally relevant amounts of selenium increases the expression of lymphocyte protein biosynthesis genes. American Journal of Clinical Nutrition 2008, 87(1), 181-189.
• Litherland GJ, Dixon C, Lakey RL, Robson T, Jones D, Young DA, Cawston TE, Rowan AD. Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3'-kinase/AKT signalling-dependent. Journal of Biological Chemistry 2008, 283(21), 14221-14229.
• Hucka M, Hoops S, Keating S, Le Novere N, Sahle S, Wilkinson DJ. Systems Biology Markup Language (SBML) Level 2: Structures and facilities for model definitions. Nature Publishing Group, 2008. Available at: http://dx.doi.org/10.1038/npre.2008.2715.1.
• Pedder CM, Ford D, Hesketh JE. Targeting of transcripts encoding membrane proteins in polarized epithelia: RNA-protein binding studies of the SGLT1 3′-UTR. Biochemical Society Transactions 2008, 36(3), 525-527.
• Ahmed S, Passos JF, Birket MJ, Beckmann T, Brings S, Peters HH, Birch-Machin MA, von Zglinicki TW, Saretzki GC. Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress. Journal of Cell Science 2008, 121(7), 1046-1053.
• Passos JF, Nelson G, von Zglinicki T. Telomeres, Senescence, Oxidative stress and heterogeneity. In: Rudolph, KL, ed. Telomeres and Telomerase in Aging, Disease, and Cancer: Molecular Mechanisms of Adult Stem Cell Ageing. Berlin: Springer, 2008, pp.43-56.
• Williams CM, Ordovas JM, Lairon D, Hesketh J, Lietz G, Gibney M, Ommen B. The challenges for molecular nutrition research 1: Linking genotype to healthy nutrition. Genes and Nutrition 2008, 3(2), 41-49.
• Gillespie CS, Renshaw E. The evolution of a single-paired immigration death process. Journal of Physics A: Mathematical and Theoretical 2008, 41(35), -.
• Sansone S, Rocca-Serra P, Brandizi M, Brazma A, Field D, Fostel J, Garrow A, Gilbert J, Goodsaid F, Hardy N, Jones P, Lister AL, Miller M, Morrison N, Rayner T, Sklyar N, Taylor C, Tong W, Warner G, Wiemann S. The first RSBI (ISA-TAB) workshop: "Can a simple format work for complex studies?". OMICS: A Journal of Integrative Biology 2008, 12(2), 143-149.
• Field D, Garrity G, Gray T, Morrison N, Selengut J, Sterk P, Tatusova T, Thomson N, Allen M, Angiuoli S, Ashburner M, Axelrod N, Baldauf S, Ballard S, Boore J, Cochrane G, Cole J, Dawyndt P, De Vos P, Depamphilis C, Edwards R, Faruque N, Feldman R, Gilbert J, Gilna P, Glöckner F, Goldstein P, Guralnick R, Haft D, Hancock D, Hermjakob H, Hertz-Fowler C, Hugenholtz P, Joint I, Kagan L, Kane M, Kennedy J, Kowalchuk G, Kottmann R, Kolker E, Kravitz S, Kyrpides N, Leebens-Mack J, Lewis S, Li K, Lister AL, Lord P, Maltsev N, Markowitz V, Martiny J, Methe B, Mizrachi I, Moxon R, Nelson K, Parkhill J, Proctor L, White O, Sansone S, Spiers A, Stevens R, Swift P, Taylor C, Tateno Y, Tett A, Turner S, Ussery D, Vaughan B, Ward N, Whetzel T, San Gil I, Wilson G, Wipat A. The minimum information about a genome sequence (MIGS) specification. Nature Biotechnology 2008, 26(5), 541-547.
• Courtot M, Bug B, Gibson F, Lister AL, Malone J, Schober D, Brinkman R, Ruttenberg A. The OWL of Biomedical Investigations. In: OWLED. 2008, Karlsruhe, Germany: W3C Web Ontology Language Workshops.
• Evans TW, Gillespie CS, Wilkinson DJ. The SBML discrete stochastic models test suite. Bioinformatics 2008, 24(2), 285-286.
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