- Project Dates: From June 2015 to November 2020
- Project Leader: Harrie Weinans (University Medical Centre Utrecht)
- Staff: Prof. John Loughlin (Institute of Cellular Medicine, Newcastle University), Dr. Jaume Bacardit (Computing Science, Newcastle University)
- Sponsors: European Innovative Medicines Initiative (IMI)
Osteoarthritis is a degenerative disease that leads to pain and deformity of the joints. Factors such as aging and trauma may contribute to injury and loss of cartilage, however the underlying biological mechanisms that cause osteoarthritis are still unknown.
The APPROACH consortium brings together a highly qualified and multidisciplinary group of stakeholders that will set up - for the first time - a broad database of different OA patients as well as a longitudinal cohort based on innovative stratification methods that identifies different osteoarthritis phenotypes. This will allow for the development of guidelines for differentially diagnosing the right patient for the right treatment.