School of Dental Sciences

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Congratulations to Dr Nick Jakubovics and his Team!

Image showing dental plaque on the surface of a tooth that was extracted due to gum disease from the research paper published by Dr Nick Jakubovics and his team has made the front cover of the Journal of Dental Research!

Many congratulations go to Dr Nick Jakubovics, Dr Nadia Rostami, Dr Richard Holliday, Prof Philip Preshaw and their team. Their research paper entitled 'A Critical Role for Extracellular DNA in Dental Plaque Formation' published in October 2016 has made the front cover of the February 2017 Journal of Dental Science. The image shows dental plaque on the surface of a tooth that was extracted due to gum disease. The plaque is made up of bacteria that stick to the tooth surface using a gluey matrix material. The project has focussed on understanding the nature of the glue that holds dental plaque together. Our talented team have shown that a significant component of it is DNA that escapes from cells when they die and are now working on new approaches to control dental plaque using an enzyme that degrades the DNA and breaks down the matrix.

 

 

 

 

 

Photo of dental plaque on the surface of a tooth that was extracted due to gum disease.
Photo of dental plaque on the surface of a tooth that was extracted due to gum disease.

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