Molecular and Cellular Basis for Specific Oral and Related Diseases
We study the molecular and cellular elements and processes which underpin oral and related systemic diseases. The two most common oral diseases, dental caries and periodontal disease, between them are responsible for the vast majority of teeth lost throughout life and they are time consuming and expensive to treat. We believe a more thorough understanding of the fundamental basis of oral disease will allow us to develop new diagnostic and therapeutic approaches and evaluate the effects of systemic health, nutrition and ageing on disease progression and incidence.
The three main research areas are:
- periodontal diseases
- molecular nutrition in healthy ageing
- fluoride metabolism and water safety
Investigations carried out within this theme provide an interface between fundamental laboratory experimental work, patient-based surveys and clinical applications. Our work exploits to the full the excellent laboratory facilities of our Cell and Molecular Biosciences Laboratory and the Fluoride Analysis Laboratory and integrates with clinical research centred within the Dental Clinical Research Facility.
Our research has been funded by the MRC, BBSRC, Diabetes UK, The NHS, the Oral and Dental Research Trust, The Dunhill Foundation, The Borrow Foundation, Philips Oral Healthcare and Organix Ltd.
For more information about this group contact: Dr John Taylor
