Dr Katrin Jaedicke
NIHR Transitional Research Fellow
- Email: firstname.lastname@example.org
- Telephone: 0191 208 7829
- Address: Newcastle University
School of Dental Sciences
Newcastle upon Tyne
I am an NIHR Fellow, working in the Institute of Cellular Medicine and the Centre for Oral Health Research, School of Dental Sciences. My interest lies within the field of salivary research, with a particular interest in salivary diagnostics.
I have been awarded a prestigious NIHR Transitional Research Fellowship to enable a move from a laboratory environment into a clinical environment, with a particular focus on improving periodontitis treatment outcome in patients with diabetes.
In 2005 I graduated from the University of Bayreuth, Germany with a Masters in Biology, specialising in Psychoneuroimmunology. I then moved to Newcastle upon Tyne for a PhD in Immunology in Periodontal Research and graduated at Newcastle University in 2010. I became a Research Assistant during my final year as PhD student and continued on as a Research Associate in two post-doctoral positions until 2014. I was awarded an NIHR Transitional Research Fellowship in 2015 to pursue my interests in patient applied research.
PhD (2010), Newcastle University
Diplom-Biologin, Univ. (2005), University of Bayreuth, Germany
Early Career Researcher Councillor on the management committee of the British Society for Oral and Dental Research.
I am currently mentoring a research associate at the School of Dental Sciences.
Peer Review Activity (alphabetical order)
· Archives of Oral Biology
· Clinical Oral Investigations
· Immunology Letters
· Journal of Clinical Periodontology
· Journal of Dentistry
· Journal of Periodontal Research
· Journal of Psychiatric Research
· Mediators of Inflammation
· Saudi Medical Journal
Since my undergraduate degree, I have a strong interest in applied immunology, enjoying the interface of lab-based immunological findings with actual clinical outcomes. I have worked with biological samples (blood, tissues, saliva, gingival crevicular fluid) to analyse effects of social stress, diabetes or periodontal disease on the immune system in a laboratory environment in both humans and animals. The clinical training I am receiving during my NIHR Fellowship now allows me to directly work with patients using salivary diagnostics and qualitative interviews. The aim of my current research is to improve compliance of patients with diabetes undergoing periodontal treatment through applying a self-monitoring feedback based on salivary diagnostics.
Fellowship: NIHR Transitional Research Fellowship (July 2014): “Do diabetic patients with periodontitis benefit from self-monitoring their periodontal inflammation profile? A feasibility study.” (£ 149,556).
Research Grant: IADR/Philips Oral Healthcare Young Investigators Research Award (April 2011): “Investigation of adiponectin isoforms in saliva as potential biomarkers in periodontal disease” ($ 10,000).
Research Grant: The Oral and Dental Research Trust (Glaxo Smith Kline) Research Grants Programme (August 2010): “Adipokines as novel salivary biomarkers in periodontal disease and diabetes” (£ 6,500).
Travel Grant: British Society for Immunology (BSI) and Newcastle University Graduate School (2010): International Association for Dental Research (IADR) General Session, 13th-17th, Barcelona, Spain.
Travel Grant: BSI and Newcastle University Graduate School (2008): BSI conference November, 17th-21st, Glasgow.
Institute of Cellular Medicine peer-led teaching (voluntary work):
Applied Statistics for Postgraduate students (four 1h sessions each term)
I have developed these lectures into an online tutorial, which is now available at:
- Jaedicke K, Preshaw PM, Taylor JJ. Salivary cytokines as biomarkers of periodontal diseases. Periodontology 2000 2016, 70(1), 164-183.
- Jitprasertwong P, Jaedicke KM, Nile CJ, Preshaw PM, Taylor JJ. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1B, from human monocytes via activation of caspase-1. Cytokine 2014, 65(2), 222-230.
- Jaedicke KM, Roythorne A, Padget K, Todryk S, Preshaw PM, Taylor JJ. Leptin up-regulates TLR2 in human monocytes. Journal of Leukocyte Biology 2013, 93(4), 561-571.
- Riis JL, Out D, Dorn LD, Beal SJ, Denson LA, Pabst S, Jaedicke KM, Granger DA. Salivary Cytokines in Healthy Adolescent Girls: Intercorrelations, Stability, and Associations with Serum Cytokines, Age and Pubertal Stage. Developmental Psychobiology 2013, 56(4), 797-811.
- Jaedicke KJ, Taylor JJ, Preshaw PM. Validation and quality control for ELISAs for use with human saliva samples. Journal of Immunological Methods 2012, 377(1-2), 62-65.
- Davies RC, Jaedicke KM, Barksby HE, Jitprasertwong P, Al-Shahwani RM, Taylor JJ, Preshaw PM. Do patients with aggressive periodontitis have evidence of diabetes? A pilot study. Journal of Periodontal Research 2011, 46(6), 663-672.
- Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM. Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide. Clinical and Experimental Immunology 2009, 156(3), 479-487.
- Jaedicke KM, Fuhrmann MD, Stefanski V. Lactation modifies stress-induced immune changes in laboratory rats. Brain, Behavior, and Immunity 2009, 23(5), 700-708.
- Greystoke A, Hogarth L, Patterson M, Williams I, Ness T, Georgiadis K, Bolt L, Bettison I, Turner D, Jamieson D, Simmons T, Hughes A, Jaedicke K, Gardiner J, Mulvenna P, Leaning D, Bradshaw A, Butler R, Black F. The introduction of the Cancer Research UK Stratified Medicine Programme 2 (CRUK SMP2) in North East England; lessons learned and experience gained. In: 14th Annual British Thoracic Oncology Group Conference 2016. 2016, Dublin, Ireland: Elsevier.
- Jaedicke KM, Wassall RR, Taylor JJ, Preshaw PM. Impact of diabetes on serum leptin concentrations in periodontitis patients. In: IADR. 2010.
- Jaedicke KM, Wassall RR, Taylor JJ, Preshaw PM. Periodontal disease is associated with increased levels of GCF adiponectin. In: IADR. 2010.
- Jaedicke KM, Preshaw PM, Taylor JJ. Leptin upregulates TLR expression in human monocytes. In: Annual Congress of the British Society for Immunology. 2008, Glasgow, Scotland: Immunology: Wiley-Blackwell.
- Riis JL, Bryce CI, Ha T, Hand T, Stebbins JL, Matin M, Jaedicke KM, Granger DA. Adiponectin: Serum-saliva associations and relations with oral and systemic markers of inflammation. Peptides 2017, 91, 58-64.