We are here to support current students within the Faculty of Medical Sciences.
Our Spring-Summer Seminar Series 2016 will start on Friday 8th April 2016 and information can be found on our seminar pages
For more information, please contact Sandra Blackwood (firstname.lastname@example.org).
100% of UK/EU tuition fees paid and annual living expenses of £14,296. Successful international candidates will be required to make up the difference between the UK/EU fees and international fees.
September 2016 for 3 years.
30 June 2016
Interested in how the ‘ageing process’ drives the development of age-related diseases? This project will investigate epigenetics mechanisms which may explain the relationship between ageing and age-related diseases.
Ageing is the main risk factor for most non-communicable diseases, including hypertension and cardiovascular disease (CVD). This risk is modified by lifestyle, and notably diet. We hypothesise that changes in mitochondrial epigenetic patterns with ageing contribute to the development of age-related disease and that dietary factors can ameliorate these effects. We will examine mechanisms that underlie ageing and their modulation by specific nutritional factors, and lay the basis for strategies to delay the development of age-related diseases.
The PhD student will develop knowledge of mitochondrial biology, ageing, age-related disease, genomics, epigenomics, nutrition, and the molecular techniques that will be used within the project, such as DNA/RNA extraction, pyrosequencing for analysing locus-specific DNA methylation, transfection using lipofectamine, and commonly used in vitro cell culture techniques. The PhD student will also learn bioinformatics tools for use in analysing the acquired DNA methylation data.
Research Excellence Academy, Faculty of Medical Sciences, Newcastle University
You must have, or expect to achieve, at least a 2:1 Honours degree in biomedicine, physiology, microbiology or a related area. A further qualification such as an MSc or MRes is advantageous.
The award is available to UK/EU and international applicants. If English is not your first language, you must have IELTS 6.5, or equivalent.
You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’.
Only mandatory fields need to be completed. However, you will need to include the following information:
For further details, please contact:
Dr H M Byun, Human Nutrition Research Centre
Institute of Cellular Medicine
Speaker 1: Kile Green (Prof M Collin, Dr V Bigley, Dr G Smith) Speaker 2: Rebecca Brown (Prof J Mathers, Dr L Avery, Dr N O'Brien) Speaker 3: Dr Pawel Palmowski (Prof N Europe-Finner)
Speaker 1: Kile Green (Prof M Collin, Dr V Bigley, Dr G Smith)
Speaker 2: Rebecca Brown (Prof J Mathers, Dr L Avery, Dr N O'Brien)
Speaker 3: Dr Pawel Palmowski (Prof N Europe-Finner)
Gene expression microarray data is typically composed of far more variables than samples. A major issue with this data format is revealed when using the data for the classification of samples or in the prediction of a clinical outcome. The problem of 'small n, large p' may be addressed through gene selection and dimension reduction under the presumption that while there are a large number of genes in the dataset, only a small number of these may actually account for the majority of the sample variation.
Over the past 10 years we can observe a rapid expansion of proteomics technologies into all branches of biological science. They have a potential to provide an in depth qualitative and quantitative characterisation of a biological system in terms of protein expression, post translational modifications and interactions. In our study we utilise proteomics tools to identify processes and pathways involved in the process of heart development/maturation
Dental Lecture Theatre F
9 March 2016, 13.00