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Molecular Cell Biology of Ageing Seminar: Understanding the neuronal control of ageing and proteostasis

Speaker: Dr Rebecca Taylor

Speaker: Dr Rebecca Taylor
Venue: EDWB.1.07 - Great Gable Seminar Room, CARU, Campus for Ageing and Vitality
Date: 26th January 2016
Time: 12:30

 

Ageing is a process associated with tissue decline and the onset of numerous diseases. Once thought to be a random process driven by accumulated damage, we now know that ageing and the onset of age-associated disease can be influenced by both genetic and environmental factors. One characteristic of ageing is an accumulation of misfolded and aggregated proteins, which underlie many of the diseases associated with old age. These proteins accumulate as a result of an age-associated failure in the cellular stress responses that detect and clear damaged proteins. Focusing on the endoplasmic reticulum unfolded protein response (UPR), we are interested in how stress responses can be manipulated to increase health and longevity. In particular, we have found that activating the UPR in the nervous system of C. elegans activates a novel signaling pathway that leads to stress response activation in other tissues. We are now exploring the signaling mechanisms that allow this stress response activation to be communicated between tissues, and utilizing multiple approaches to understand how systemic stress response activation leads to increased health and longevity, with a view to harnessing this pathway for disease treatment.


Industry Engagement Day

The Industry Engagement Day is to strengthen existing and foster new collaborations between Newcastle Academic Health Partners (NAHP) and Industry in early phase clinical research. Admission: Free to Newcastle University/Newcastle Hospitals NHS Trust/ £50 Industry and external organisations. Contact for further information: Ben Fisher Tel: 0191 208 3421 Email: ben.fisher2@newcastle.ac.uk

The Industry Engagement Day is to strengthen existing and foster new collaborations between Newcastle Academic Health Partners (NAHP) and Industry in early phase clinical research. Admission: Free to Newcastle University/Newcastle Hospitals NHS Trust/ £50 Industry and external organisations. Contact for further information: Ben Fisher Tel: 0191 208 3421 Email: ben.fisher2@newcastle.ac.uk

http://conferences.ncl.ac.uk/engagingwithindustry/ 

 


Performing Research Group event

Join the Performing Research group and explore how theatre and drama can be used to develop public engagement and academic impact and complement your research and teaching skills! Admission: Free. Contact for further information: Katy Tel: 07796 478 024 Email: katy@cap-a-pie.co.uk

VOICENorth Research Support Group

VOICENorth Research Support Group

  • Are you looking for early public involvement in your research?
  • Would you like feedback on your research proposal or lay information materials?
  • Are you seeking help to shape a new research project.

The VOICENorth Reearch Support Group are here for you!

The group are here to help you by providing insights, from the early stages of generating project ideas, to giving feedback on lay summaries and other research documentation. A particular focus is research on ageing and conditions that may affect you in later life. They are keen to get involved and aim to enhance research by sharing their vast experience and mental capital.

This free service is provided by VOICENorth and the Faculty of Medical Sciences Engagement team to help improve research and public involvement across the Faculty.

Places are limited to allow for meaningful discussion with the group. To request a place at a future meeting please fill out a form at:

www.tinyurl.com/RSGrequest

For further information please contact:

voicenorth@ncl.ac.uk or call 0191 208 1288 


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