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ICM Research Seminar

Speaker 1: Ashleigh McConnell

Speaker 2: Gabriel Cantanhede 

1: CXCR4, CXCR7 and CXCL12 Expression and Cell Signalling in Cutaneous Melanoma

Ashleigh will talk about he prognostic signficance and impact of the CXCR4-CXCR7-CXCL12 axis in primary cutaneous melanoma 


2: The role of class II Human Leukocyte Antigens in Chronic Kidney Transplant Rejection


Gabriel will talk about Antibody-mediated rejection is one of the major causes of chronic rejection. This is mediated by endothelial cell activation, a process of endothelium microvascular inflammation and leukocyte recruitment. Evidence pointing to the relevance of HLA class II antibody in graft rejection is abundant, but the role of antibody-endothelium interaction in the absence of complement has not been fully understood. This project seeks to identify signalling cascades activated by HLA class II antibodies and mechanisms mediating endothelial cell – leukocyte interaction



Kay Howes appointed new Faculty Research Manager


I’m delighted to have been appointed Faculty Research Manager.  This is a new role and I will be working with the Deans of Research to devise and implement research strategy including driving forward key projects, developing collaboration across Institutes and Faculties and, importantly, leading preparations for the next Research Excellence Framework.  Prior to taking up this post I was seconded to Newcastle Clinical Trials Unit as Operations Manager and before that I managed the Institute of Cellular Medicine.

MILAN Film Festival 2016

Location: David Shaw Lecture Theatre 
Time/Date: 15th February 2016 - 19th February 2016, 18:30 

Come and join us for a week of film screenings and discussion that explores how movies and books can enrich our understanding of what it means to be human and how collaboration with the arts and humanities can broaden medical education.

Open to all staff and students at Newcastle University 

Admission is FREE and you are encouraged to attend as many films as you like (discussions will be varied in topic and mode of presentation)

Screenings are for educational purposes.

Doors 6.30pm, Screenings 7pm, Post-film discussions (30mins of panel discussion with Q&A from the audience)

Monday - Inside Out

Tuesday - Algorithms

Wednesday - Shame

Thursday - The Diving Bell And The Butterfly

Friday - 50/50 

Book tickets here 

Medical School Entrance is found on this campus map  Number 60


Writing in Health

This workshop aims to provide a nurturing space for expression of participants’ experience of health and ill health through a variety of writing exercises, in both poetry and prose.

Christy Ducker is a poet and tutor. Work from her first collection, Skipper (smith/doorstop, 2015) was commended by the Forward Prize judges. Her pamphlet, Armour (smith/doorstop, 2011) was a Poetry Book Society Pamphlet Choice.

Eleanor Holmes is a General Practitioner, medical educator and writer who lives and works in the North East of England. She is currently looking to publish her first poetry pamphlet, Flora Speaks.

Sue Spencer is a writer, educator and facilitator. She is an alumnus of the MA in Poetry at Newcastle University and is the Poetry Adviser for the BMJ Journal Medical Humanities.


Creative Saturdays are one-day creative writing workshops led by celebrated authors and supported by writers from NCLA. Workshops are held in the Percy Building, Newcastle University, from 10am to 4pm. Please bring your own lunch; tea and coffee will be provided. The course fee is £40 per workshop. 


Book now on the Webstore.  

Molecular Cell Biology of Ageing Seminar: Understanding the neuronal control of ageing and proteostasis

Speaker: Dr Rebecca Taylor

Speaker: Dr Rebecca Taylor
Venue: EDWB.1.07 - Great Gable Seminar Room, CARU, Campus for Ageing and Vitality
Date: 26th January 2016
Time: 12:30


Ageing is a process associated with tissue decline and the onset of numerous diseases. Once thought to be a random process driven by accumulated damage, we now know that ageing and the onset of age-associated disease can be influenced by both genetic and environmental factors. One characteristic of ageing is an accumulation of misfolded and aggregated proteins, which underlie many of the diseases associated with old age. These proteins accumulate as a result of an age-associated failure in the cellular stress responses that detect and clear damaged proteins. Focusing on the endoplasmic reticulum unfolded protein response (UPR), we are interested in how stress responses can be manipulated to increase health and longevity. In particular, we have found that activating the UPR in the nervous system of C. elegans activates a novel signaling pathway that leads to stress response activation in other tissues. We are now exploring the signaling mechanisms that allow this stress response activation to be communicated between tissues, and utilizing multiple approaches to understand how systemic stress response activation leads to increased health and longevity, with a view to harnessing this pathway for disease treatment.

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