Dr Catherine Meplan
Senior Research Associate
- Email: catherine.meplan@ncl.ac.uk
- Telephone: +44 (0) 191 222 8355
- Address: Institute for Cell and Molecular Biosciences
Medical School
Newcastle University
Framlington Place
Newcastle upon Tyne
NE2 4HH
- Hughes DJ, Jenab M, Meplan C, Schomburg L, Prehn J, Hesketh JE. Colorectal Cancer Risk - the Influence of Selenoprotein Gene Variants and Blood Selenium Status.
In: 22nd Biennial Congress of the European Association for Cancer Research. 2012, Barcelona, Spain: Pergamon.
- Gong G, Meplan C, Gautrey H, Hall J, Hesketh JE. Differential effects of selenium and knock-down of glutathione peroxidases on TNF alpha and flagellin inflammatory responses in gut epithelial cells.
Genes & Nutrition 2012, 7(2), 167-178.
- Steinbrecher A, Méplan C, Hesketh J, Schomburg L, Endermann T, Jansen E, Åkesson B, Rohrmann S, Linseisen J. Effects of selenium status and polymorphisms in selenoprotein genes on prostate cancer risk in a prospective study of European men.
Cancer Epidemiology Biomarkers and Prevention 2010, 19(11), 2958-2968.
- Mathers JC, Meplan C, Hesketh JE. Polymorphisms Affecting Trace Element Bioavailability.
International Journal for Vitamin and Nutrition Research 2010, 80(4-5), 314-318.
- Kipp A, Banning A, van Schothorst EM, Meplan C, Schomburg L, Evelo C, Coort S, Gaj S, Keijer J, Hesketh J, Brigelius Flohe R. Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon.
Molecular Nutrition & Food Research 2009, 53(12), 1561-1572.
- Meplan C, Nicol F, Burtle BT, Crosley LK, Arthur JR, Mathers JC, Hesketh JE. Relative Abundance of Selenoprotein P Isoforms in Human Plasma Depends on Genotype, Se Intake, and Cancer Status.
Antioxidants & Redox Signaling 2009, 11(11), 2631-2640.
- Leung WC, Hessel S, Méplan C, Flint J, Oberhauser V, Tourniaire F, Hesketh JE, von Lintig J, Lietz G. Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers.
FASEB Journal 2009, 23(4), 1041-1053.
- Meplan C, Crosley LK, Nicol F, Horgan GW, Mathers JC, Arthur JR, Hesketh JE. Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: Interaction with sex.
American Journal of Clinical Nutrition 2008, 87(4), 1019-1027.
- Pagmantidis V, Meplan C, Van Schothorst EM, Keijer J, Hesketh JE. Supplementation of healthy volunteers with nutritionally relevant amounts of selenium increases the expression of lymphocyte protein biosynthesis genes.
American Journal of Clinical Nutrition 2008, 87(1), 181-189.
- Crosley LK, Meplan C, Nicol F, Rundlof AK, Arner ESJ, Hesketh JE, Arthur JR. Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney.
Archives of Biochemistry and Biophysics 2007, 459(2), 178-188.
- Meplan C, Crosley LK, Nicol F, Beckett GJ, Howie AF, Hill KE, Horgan G, Mathers JC, Arthur JR, Hesketh JE. Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study).
FASEB Journal 2007, 21(12), 3063-3074.
- Meplan C, Crosley K, Nicol F, Arthur JR, Mathers JC, Hesketh JE. Influences of gender and genetic variation in the 3 ' untranslated region of the glutathione peroxidise 4 gene on the response to selenium supplementation in healthy volunteers.
In: Proceedings of the Nutrition Society. 2006, Aberdeen, Scotland: Cambridge University Press.
