Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts (2010)

Author(s): Nooteboom M, Johnson R, Taylor RW, Wright NA, Lightowlers RN, Kirkwood TBL, Mathers JC, Turnbull DM, Greaves LC

      • Date: 01-02-2010
      • Journal: Aging Cell
      • Volume: 9
      • Issue: 1
      • Pages: 96-99
      • Publisher: Wiley-Blackwell Publishing Ltd.
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: aging colon mitochondrial DNA respiratory chain stem cells SEQUENCE HETEROGENEITY STEM-CELLS DISEASE MTDNA MECHANISMS LINEAGES TISSUES MICE


      Professor John Mathers
      Professor of Human Nutrition