IAH Seminar - Blood pressure variability, cognitive impairment and cognitive decline in community dwelling older people.

Location: Great Gable Meeting Room, Clinical Ageing Research Unit, CAV
Time/Date: 9th February 2012, 12:15 - 13:00

You are invited to the IAH research seminar which will take place on Thursday 9 February 2012 which will be held in the Great Gable meeting room of the Clinical Ageing Research Unit. The meeting will start at 12.15 and will be followed at approximately 13.00 by a sandwich lunch.

The presentation today will be given by Dr Claire McDonald, Age UK Clinical Research Fellow in the IAH and the title of her talk is 'Blood pressure variability, cognitive impairment and cognitive decline in community dwelling older people'.

Abstract:

Hypertension is a well recognised risk factor for dementia.  More recently studies have suggest low blood pressure (BP) may also be a risk factor for cognitive impairment and cognitive decline, possibly because a critical blood pressure is necessary to maintain cerebral perfusion and preserve cognitive ability.

Twenty four hour ambulatory blood pressure monitoring (ABPM) is increasingly employed in the assessment of BP. ABPM profiles mean 24- hr BP and  BP variability. We propose that increased BP variability may result in impaired cognitive function as a consequence of episodic cerebral hypotension.

n this study we accessed blood pressure variability and cognitive function in community dwelling older people. Cognitive assessments took place at baseline and after 5 years follow-up. We showed that increased blood pressure variability is associated with impaired cognitive function and greater cognitive decline.

Published: 13th January 2012